IMAG_Wiki - Recent changes [en]

Multiscale Systems Biology Working Group

2012-05-15T17:04:35Z

List of Participants:

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	Bridget Wilson, University of New Mexico<br>		Bridget Wilson, University of New Mexico<br>
	Raimond Winslow, Johns Hopkins Univ.<br>		Raimond Winslow, Johns Hopkins Univ.<br>
		+	Charles Wolgemuth, Univ. of Arizona<br>
		+	Yi Wu, Univ. of Connecticut Health Center<br>
	Lingchong You, Duke Univ.<br>		Lingchong You, Duke Univ.<br>
	Wang Yu-Ping, Tulane Univ.<br>		Wang Yu-Ping, Tulane Univ.<br>
	Xiaobo Zhou, TMHRI & Weill Cornell<br>		Xiaobo Zhou, TMHRI & Weill Cornell<br>

Main Page

2012-05-15T16:22:35Z

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	*Editorial: '''What Biomedical Engineers can do to Impact Multiscale Modeling''' (TBME Letters Special Issue on Multiscale Modeling and Analysis in computational Biology and Medicine: Part-2)<br />		*Editorial: '''What Biomedical Engineers can do to Impact Multiscale Modeling''' (TBME Letters Special Issue on Multiscale Modeling and Analysis in computational Biology and Medicine: Part-2)<br />
	</li>		</li>
-	</ul><br /><br /><br /><br />	+	</ul><br /><br /><br /><br /><br /><br /><br />
	</td></tr>		</td></tr>
	</table></td>		</table></td>
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	Dr. Vasilis Marmarelis</b><br />		Dr. Vasilis Marmarelis</b><br />
	This talk seeks to stimulate our thinking on the synergistic use of data-based and hypothesis-based modeling methods in a practical context. It will summarize our findings to date and will present illustrative examples from neural and metabolic systems where this synergistic approach has yielded useful insights. <br />		This talk seeks to stimulate our thinking on the synergistic use of data-based and hypothesis-based modeling methods in a practical context. It will summarize our findings to date and will present illustrative examples from neural and metabolic systems where this synergistic approach has yielded useful insights. <br />
-	<b>~~Adobe Connect~~: https://webmeeting.nih.gov/~~r72881502~~/</b>	+	<b>Archived Recording: https://webmeeting.nih.gov/p79925002/</b> <br />
	FOR COMPLETE DETAILS, please see: http://www.imagwiki.nibib.nih.gov/mediawiki/index.php?title=WG_Webinar_Series		FOR COMPLETE DETAILS, please see: http://www.imagwiki.nibib.nih.gov/mediawiki/index.php?title=WG_Webinar_Series
	</li></ul><br /><br /><br />		</li></ul><br /><br /><br />
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	<b>Application Due Date: May 18, 2012</b> <br />		<b>Application Due Date: May 18, 2012</b> <br />
	[http://grants.nih.gov/grants/guide/pa-files/PAR-10-141.html More Information]		[http://grants.nih.gov/grants/guide/pa-files/PAR-10-141.html More Information]
-	</li></ul~~><br /~~>	+	</li></ul>
	<big><b><center>[[New Funding Opportunities\|More Funding Opportunities...]]</center></b></big>		<big><b><center>[[New Funding Opportunities\|More Funding Opportunities...]]</center></b></big>
	</td></tr>		</td></tr>
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	<tr><td align="left" bgcolor="#E7E7FB" valign="top" style=height:150px>		<tr><td align="left" bgcolor="#E7E7FB" valign="top" style=height:150px>
	<ul>		<ul>
-	~~<li><b>April 30-May 5, 2012: Multiscale Modeling in Computational Neuroscience</b><br />~~
-	~~University of Lubeck, Lubeck, Germany<br />~~
-	~~[https://www.gradschool.uni-luebeck.de/index.php?id=366 More Information]<br /></li>~~
	<li><b>May 30-June 1, 2012: NSF Summer Institute Short Course on Materiomics—Merging Biology and Engineering in Multiscale Structures and Materials</b><br />		<li><b>May 30-June 1, 2012: NSF Summer Institute Short Course on Materiomics—Merging Biology and Engineering in Multiscale Structures and Materials</b><br />
	MIT, LeMeridien Hotel<br />		MIT, LeMeridien Hotel<br />
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	<li><b>July 15-19, 2012: “Computational Modeling for Human Health and Performance Analysis” at the 42nd International Conference on Environmental Systems'''</b><br />		<li><b>July 15-19, 2012: “Computational Modeling for Human Health and Performance Analysis” at the 42nd International Conference on Environmental Systems'''</b><br />
	San Diego, CA<br />		San Diego, CA<br />
-	[https://www.aiaa.org/ICES2012/ More Information]	+	[https://www.aiaa.org/ICES2012/ More Information]<br />
	</ul>		</ul>
	<big><b><center>[[New Meeting Announcements\|More Upcoming Meetings...]]</center></b></big>		<big><b><center>[[New Meeting Announcements\|More Upcoming Meetings...]]</center></b></big>

Multiscale Systems Biology Working Group

2012-05-14T14:07:42Z

List of Participants:

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	Jennifer Linderman, Univ. of Michigan<br>		Jennifer Linderman, Univ. of Michigan<br>
	Leslie Loew, Univ. of Connecticut<br>		Leslie Loew, Univ. of Connecticut<br>
		+	Joanne Luciano, Rensselaer Polytech. Inst.<br>
	Feilim Mac Gabhann, Johns Hopkins Univ.<br>		Feilim Mac Gabhann, Johns Hopkins Univ.<br>
	Madhav Marathe, Virginia Tech<br>		Madhav Marathe, Virginia Tech<br>

2012 MSM CONSORTIUM MEETING

2012-05-11T21:31:02Z

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	:#Can we develop general MSM tools that work in multiple domains? Can we use such tools already developed in other domains?		:#Can we develop general MSM tools that work in multiple domains? Can we use such tools already developed in other domains?
	:#In addition to the MSM models, what other infrastructure is needed (hardware, data, networks, software, services, etc.)? Does all the infrastructure that we need exist? Is it useable in both development and clinical settings? If not, what are the technical, policy, or other issues that prevent it from being usable?		:#In addition to the MSM models, what other infrastructure is needed (hardware, data, networks, software, services, etc.)? Does all the infrastructure that we need exist? Is it useable in both development and clinical settings? If not, what are the technical, policy, or other issues that prevent it from being usable?
		+
		+
		+	'''Other suggestions for the meeting:'''
		+	* Networking time debating MSM Challenges - brainstorming a MSM Prize competition
		+	* PAR-11-203 Pow Wow - grants application and review issues
		+	* Moving the field forward - are we making an impact?

	<br />		<br />

WG Webinar Series

2012-05-11T20:46:16Z

← Older revision		Revision as of 20:46, 11 May 2012
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	'''Note:''' if you intend to broadcast this webinar in a classroom setting, all questions should be typed into the '''chat box''' during the presentation.		'''Note:''' if you intend to broadcast this webinar in a classroom setting, all questions should be typed into the '''chat box''' during the presentation.

		+	INSTRUCTIONS FOR AUDIO:When you enter the meeting room, click the yellow telephone icon at the bottom of the Attendee list pod then click "Start Audio Conference", enter your own telephone number when prompted and click "Call my phone". When your telephone rings, answer it and follow the voice prompts.

-	*'''Friday May 11 at 1:00pm EDT'''
-	~~:Adobe Connect: https://webmeeting.nih.gov/r72881502/~~

-	:{When you enter the meeting room, click the yellow telephone icon at the bottom of the Attendee list pod then click "Start Audio Conference", enter your own telephone number when prompted and click "Call my phone". When your telephone rings, answer it and follow the voice prompts.}

		+	*'''Friday May 11 at 1:00pm EDT'''
		+
		+	'''Archived Recording: https://webmeeting.nih.gov/p79925002/'''

User:RigasM

2012-05-10T18:52:02Z

← Older revision		Revision as of 18:52, 10 May 2012
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	== Marc Rigas, Ph.D. ==		== Marc Rigas, Ph.D. ==

-	'''~~NCRR (NIH)~~'''	+	'''NSF'''


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	'''Contact Information'''		'''Contact Information'''

-	Email: ~~rigasm~~@~~mail.nih~~.gov	+	Email: mrigas@nsf.gov

Listing of IMAG Participants

2012-05-10T18:48:34Z

NSF

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	<tr> <td>Misha Pavel</td> <td> CISE</td> <td>mpavel@nsf.gov		<tr> <td>Misha Pavel</td> <td> CISE</td> <td>mpavel@nsf.gov
	</tr>		</tr>
-	<tr> <td>[[User:RigasM\|Marc Rigas]] </td> <td> ~~NCRR~~ </td> <td> mrigas@nsf.gov	+	<tr> <td>[[User:RigasM\|Marc Rigas]] </td> <td> </td> <td> mrigas@nsf.gov
	</tr>		</tr>
	<tr> <td>[[User:RussellT\|Tom Russell]]</td> <td> Mathematical Sciences (DMS) </td> <td> trussell@nsf.gov		<tr> <td>[[User:RussellT\|Tom Russell]]</td> <td> Mathematical Sciences (DMS) </td> <td> trussell@nsf.gov

Main Page

2012-05-10T18:47:46Z

← Older revision		Revision as of 18:47, 10 May 2012
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	<b>Adobe Connect: https://webmeeting.nih.gov/r72881502/</b>		<b>Adobe Connect: https://webmeeting.nih.gov/r72881502/</b>
	FOR COMPLETE DETAILS, please see: http://www.imagwiki.nibib.nih.gov/mediawiki/index.php?title=WG_Webinar_Series		FOR COMPLETE DETAILS, please see: http://www.imagwiki.nibib.nih.gov/mediawiki/index.php?title=WG_Webinar_Series
-	</li></ul~~><br /><br /><br /><br /~~><br /><br /><br />	+	</li></ul><br /><br /><br />
	<big><b><center>[[Multiscale Modeling Working Groups\|Working Group Pages]]</center></b></big>		<big><b><center>[[Multiscale Modeling Working Groups\|Working Group Pages]]</center></b></big>
	</td></tr>		</td></tr>

Main Page

2012-05-10T17:29:37Z

← Older revision		Revision as of 17:29, 10 May 2012
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	This talk seeks to stimulate our thinking on the synergistic use of data-based and hypothesis-based modeling methods in a practical context. It will summarize our findings to date and will present illustrative examples from neural and metabolic systems where this synergistic approach has yielded useful insights. <br />		This talk seeks to stimulate our thinking on the synergistic use of data-based and hypothesis-based modeling methods in a practical context. It will summarize our findings to date and will present illustrative examples from neural and metabolic systems where this synergistic approach has yielded useful insights. <br />
	<b>Adobe Connect: https://webmeeting.nih.gov/r72881502/</b>		<b>Adobe Connect: https://webmeeting.nih.gov/r72881502/</b>
		+	FOR COMPLETE DETAILS, please see: http://www.imagwiki.nibib.nih.gov/mediawiki/index.php?title=WG_Webinar_Series
	</li></ul><br /><br /><br /><br /><br /><br /><br />		</li></ul><br /><br /><br /><br /><br /><br /><br />
	<big><b><center>[[Multiscale Modeling Working Groups\|Working Group Pages]]</center></b></big>		<big><b><center>[[Multiscale Modeling Working Groups\|Working Group Pages]]</center></b></big>

Main Page

2012-05-10T17:26:50Z

← Older revision		Revision as of 17:26, 10 May 2012
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	<tr><td align="left" bgcolor="#E7E7FB" valign="top" style=height:150px><ul>		<tr><td align="left" bgcolor="#E7E7FB" valign="top" style=height:150px><ul>
	<li><b>Friday May 11 at 1:00pm eastern: </b><br />		<li><b>Friday May 11 at 1:00pm eastern: </b><br />
-	Synergistic Use of Data-based and Hypothesis-based Modeling of Biomedical Dynamic Systems<br />	+	<b>Synergistic Use of Data-based and Hypothesis-based Modeling of Biomedical Dynamic Systems<br />
-	Dr. Vasilis Marmarelis<br />	+	Dr. Vasilis Marmarelis</b><br />
-	<b>~~Audio:~~</b> ~~800~~-~~857~~-~~6564 <b>Passcode:</b>30019~~<br />	+	This talk seeks to stimulate our thinking on the synergistic use of data-based and hypothesis-based modeling methods in a practical context. It will summarize our findings to date and will present illustrative examples from neural and metabolic systems where this synergistic approach has yielded useful insights. <br />
	<b>Adobe Connect: https://webmeeting.nih.gov/r72881502/</b>		<b>Adobe Connect: https://webmeeting.nih.gov/r72881502/</b>
	</li></ul><br /><br /><br /><br /><br /><br /><br />		</li></ul><br /><br /><br /><br /><br /><br /><br />

MSM Consortium FAQs

2012-05-09T20:07:20Z

What is the history of the MSM Consortium?

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	A history of the MSM Consortium is described on the [http://www.nibib.nih.gov/Research/IMAG MSM] website		A history of the MSM Consortium is described on the [http://www.nibib.nih.gov/Research/IMAG MSM] website

-	[[~~Image~~:~~IMAGhistorytimelinev7~~.~~PNG‎~~]]	+	[[File:IMAGhistorytimeline 2012.png\|thumb\|750px]]<br />
		+

	'''Contacts:'''		'''Contacts:'''

File:IMAGhistorytimeline 2012.png

2012-05-09T19:57:43Z

uploaded a new version of "[[File:IMAGhistorytimeline 2012.png]]"

File:IMAGhistorytimeline 2012.png

2012-05-09T19:56:24Z

uploaded "[[File:IMAGhistorytimeline 2012.png]]"

MSM Consortium FAQs

2012-05-09T19:25:52Z

What is the history of the MSM Consortium?

← Older revision		Revision as of 19:25, 9 May 2012
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	===What is the history of the MSM Consortium?===		===What is the history of the MSM Consortium?===
-	A history of the MSM Consortium is described on the [http://www.nibib.nih.gov/Research/~~MultiScaleModeling~~ MSM] website	+	A history of the MSM Consortium is described on the [http://www.nibib.nih.gov/Research/IMAG MSM] website

	[[Image:IMAGhistorytimelinev7.PNG‎]]		[[Image:IMAGhistorytimelinev7.PNG‎]]

Listing of IMAG Participants

2012-05-08T20:30:37Z

Interagency Modeling and Analysis Group (IMAG) List of Participants

← Older revision		Revision as of 20:30, 8 May 2012
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	</tr>		</tr>
	<tr> <td>[[User:RemingtonK\|Karin Remington]] </td> <td> NIGMS </td> <td> remingka@mail.nih.gov		<tr> <td>[[User:RemingtonK\|Karin Remington]] </td> <td> NIGMS </td> <td> remingka@mail.nih.gov
-	~~</tr>~~
-	~~<tr> <td>[[User:RigasM\|Marc Rigas]] </td> <td> NCRR </td> <td> rigasm@mail.nih.gov~~
	</tr>		</tr>
	<tr> <td>[[User:RodgersM\|Mary Rodgers]] </td> <td> NIBIB </td> <td> mary.rodgers@nih.gov		<tr> <td>[[User:RodgersM\|Mary Rodgers]] </td> <td> NIBIB </td> <td> mary.rodgers@nih.gov
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	</tr>		</tr>
	<tr> <td>Misha Pavel</td> <td> CISE</td> <td>mpavel@nsf.gov		<tr> <td>Misha Pavel</td> <td> CISE</td> <td>mpavel@nsf.gov
		+	</tr>
		+	<tr> <td>[[User:RigasM\|Marc Rigas]] </td> <td> NCRR </td> <td> mrigas@nsf.gov
	</tr>		</tr>
	<tr> <td>[[User:RussellT\|Tom Russell]]</td> <td> Mathematical Sciences (DMS) </td> <td> trussell@nsf.gov		<tr> <td>[[User:RussellT\|Tom Russell]]</td> <td> Mathematical Sciences (DMS) </td> <td> trussell@nsf.gov

WG Webinar Series

2012-05-08T14:34:47Z

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	Return to [[Multiscale Modeling Working Groups]]		Return to [[Multiscale Modeling Working Groups]]

-	~~This webinar series will be recorded and archived.~~

		+	'''This webinar series will be recorded and archived.'''

-	*'''~~Friday May 11 at 1~~:~~00 eastern~~'''	+	'''Note:''' if you intend to broadcast this webinar in a classroom setting, all questions should be typed into the '''chat box''' during the presentation.
-	~~:Synergistic Use of Data-based and Hypothesis-based Modeling of Biomedical Dynamic Systems~~	+
-	~~:Dr~~. ~~Vasilis Marmarelis~~	+

-	*'''Friday June 8 at 1:~~00 eastern~~'''	+
		+	*'''Friday May 11 at 1:00pm EDT'''
		+	:Adobe Connect: https://webmeeting.nih.gov/r72881502/
		+
		+	:{When you enter the meeting room, click the yellow telephone icon at the bottom of the Attendee list pod then click "Start Audio Conference", enter your own telephone number when prompted and click "Call my phone". When your telephone rings, answer it and follow the voice prompts.}
		+
		+
		+
		+	'''Synergistic Use of Data-based and Hypothesis-based Modeling of Biomedical Dynamic Systems, Vasilis Z. Marmarelis, Ph.D.'''
		+
		+	The inductive (data-based) and the deductive (hypothesis-based) approaches have played a complementary and mutually beneficial role in the history of science, whereby observations have led to the postulation of hypotheses that are subsequently tested by properly designed experiments. This forms an evolutionary process of hypothesis formulation and testing, leading to scientific advancement. In life sciences and medicine, the importance of discovering and quantifying the physiological mechanisms under normal and pathological conditions has given rise to mechanism-based modeling methods (e.g. compartmental or structural modeling) which rely on the current state of understanding of the system under study. However, the intrinsic complexity of physiological systems and the need for validation of the structural models present formidable challenges in the mechanism-based approach and motivate the complementary use of data-based modeling approaches (typically input-output or stimulus-response formulations). The latter seek to capture the essential functional characteristics of the physiological system in a manner consistent with the available data. Subsequent analysis of the obtained data-based models suggest hypothesis-based model forms that encapsulate the relevant physiological mechanisms and can be tested through properly designed experiments. In this process, the data-based model serves as “ground truth” for the validity of an equivalent hypothesis-based or mechanism-based model. Our experience over the last 30 years shows that this “virtuous cycle” of model development is enabled by the synergistic use of data-based and hypothesis-based approaches.
		+	The study of functional and structural complexity in living systems requires reliable and robust modeling tools in a hierarchical context of multiple scales of time and space. Although mechanism-based models remain the ultimate objective of multi-scale modeling, data-based models can be helpful in pursuing this goal because of their applicability to arbitrary levels of systemic organization from molecular to cellular to multi-cellular to organ to multi-organ etc. This broad applicability depends on appropriate methods of modeling/analysis within the constraints imposed by experimental limitations. This talk seeks to stimulate our thinking on the synergistic use of data-based and hypothesis-based modeling methods in a practical context. It will summarize our findings to date and will present illustrative examples from neural and metabolic systems where this synergistic approach has yielded useful insights.
		+
		+
		+	*'''Friday June 8 at 1:00pm EDT'''
	:Specification, construction, and exact reduction of state transition system models of biochemical processes		:Specification, construction, and exact reduction of state transition system models of biochemical processes
	:Drs. Dan Beard and Scott Bugenhagen		:Drs. Dan Beard and Scott Bugenhagen

-	*'''Friday July 13 at 1:~~00 eastern~~'''	+	*'''Friday July 13 at 1:00pm EDT'''
	:Multi-scale Image-based models for CFD simulations of pulmonary air flow		:Multi-scale Image-based models for CFD simulations of pulmonary air flow
	:Dr. Youbing Yin		:Dr. Youbing Yin