Model number
0305

A FORTRAN based model for triple-labeled indicator dilution experiments in a four region tissue exchange model with 20 flow paths. WILL NOT RUN ON PC (MS Windows) COMPUTERS IF DOWNLOADED, BUT CAN BE RUN OVER THE WEB AS AN APPLET.

Further reading:     Distributed Blood Tissue Exchange Models Explained

Further reading:     MMID4 manual (XSIM version)

Description

fig 1

fig2


A FORTRAN based model for triple-labeled indicator dilution experiments in a four region tissue exchange model with 20 flow paths. WILL NOT RUN ON PC COMPUTERS IF DOWNLOADED, BUT CAN BE RUN OVER THE WEB AS AN APPLET.

The manual for the XSIM version is useful in explaining the model. The manual has not been revised for the JSim implementation. Contact garyr at uw dot edu if you need further assistance.

 

 

 

 

 

 

 

 

 

 

 

Equations

  Vascular Equations

 

     Differential Equation

e0

     Left Boundary Condition

e1

    Right Boundary Conditions

e2  ,  e3

     Initial Conditions

e4  or  e5

 

  Extracellular Equations

 

     Differential Equations

e6

e7

    Left Boundary Conditions

e8  ,  e9

    Right Boundary Conditions

e10  ,  e11  ,  e12

     Initial Conditions

e13  ,  e14  or  e15

 

  Permeant Equations

 

     Differential Equations

e16

e17

e18

e19

    Left Boundary Conditions

e20 ,  e21 ,  e22,  e23

    Right Boundary Conditions

e24  ,  e25  ,  e26  ,  e27  ,  e28

     Initial Conditions

e29  ,  e30  ,  e31  ,  e32  or  e33 ,   ,   ,   .

 

The equations for this model may be viewed by running the JSim model applet and clicking on the Source tab at the bottom left of JSim's Run Time graphical user interface. The equations are written in JSim's Mathematical Modeling Language (MML). See the Introduction to MML and the MML Reference Manual. Additional documentation for MML can be found by using the search option at the Physiome home page.

Download JSim model project file

Help running a JSim model.

References

None.

Acknowledgements

Please cite https://www.imagwiki.nibib.nih.gov/physiome in any publication for which this software is used and send one reprint to the address given below:
The National Simulation Resource, Director J. B. Bassingthwaighte, Department of Bioengineering, University of Washington, Seattle WA 98195-5061.

Model development and archiving support at https://www.imagwiki.nibib.nih.gov/physiome provided by the following grants: NIH U01HL122199 Analyzing the Cardiac Power Grid, 09/15/2015 - 05/31/2020, NIH/NIBIB BE08407 Software Integration, JSim and SBW 6/1/09-5/31/13; NIH/NHLBI T15 HL88516-01 Modeling for Heart, Lung and Blood: From Cell to Organ, 4/1/07-3/31/11; NSF BES-0506477 Adaptive Multi-Scale Model Simulation, 8/15/05-7/31/08; NIH/NHLBI R01 HL073598 Core 3: 3D Imaging and Computer Modeling of the Respiratory Tract, 9/1/04-8/31/09; as well as prior support from NIH/NCRR P41 RR01243 Simulation Resource in Circulatory Mass Transport and Exchange, 12/1/1980-11/30/01 and NIH/NIBIB R01 EB001973 JSim: A Simulation Analysis Platform, 3/1/02-2/28/07.