Invasive Approach to Model Human Cortex-Basal Ganglia Action-Regulating Networks

Investigator Names  Nader Pouratian, Ueli Rutishauser, Adam Aron, Vasileios Chriostpoulos
Institutions UC Los Angeles, Cedars-Sinai Medical Center, UC San Diego, UC Riverside
Grant support: NIH BRAIN Initiative, NINDS U01 NS098961
Performance period  Dec 2016-Nov 2020



Goal: We aim to investigate the spatiotemporal dynamics of basal ganglia-cortical network activity regulating human motor control  


Study population and setting:

  • Patients with Parkinson disease undergoing deep brain stimulatin implantation surgery
  • Intraoperative recordings of spikes, deep brain local field potentials from basal ganglia, and electrocorticography from motor, prefrontal, and parietal cortices while participants perform choice, conflict, and action suppression tasks.

Data generated:


Back to ROH Main Page

Table sorting checkbox