| Investigator Names | Nanthia Suthana, Barbara Knowlton, Itzhak Fried, John Stern, Dawn Eliashiv, Matthias Stangl, Vikram Rao, Cory Inman, Casey Halpern, Vivek Buch |
| Institutions | University of California Los Angeles, University of California San Francisco, University of Utah, University of Pennsylvania, Stanford University |
| Grant support: | NIH BRAIN, U01NS117838 |
| Performance period | 2020-2025 |
Goal: The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world memory tasks. We will determine the cognitive (i.e., memory) and behavioral (i.e., body, head, eye position and movement) factors that modulate deep brain activity and the consequent effects of memory-enhancing deep brain stimulation.
Study population and setting:
- Participants implanted with the NeuroPace Responsive Neurostimulator (RNS®) for clinical evaluation and treatment of epilepsy.
- NeuroPace RNS
Data generated:
- Local field potentials, eye tracking data, scalp EEG data, motion tracking data, and behavior. We use the DABI archive for the release of datasets.
Resources:
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