National Institute of Health

Notice of Special Interest (NOSI): Administrative Supplements to Support the Development of Digital Twins in Radiation Oncology (DTRO)

The Division of Cancer Treatment and Diagnosis (DCTD) and the Center for Biomedical Informatics and Information Technology (CBIIT) at the National Cancer Institute (NCI) announce the Digital Twins Radiation Oncology (DTRO) administrative supplement opportunity that seeks to support collaborative, multidisciplinary research in radiation oncology in the development of digital twins. For the purposes of this notice, a digital twin as defined by the 

Interactive Digital Media (IDM) Biomedical Science Resources for Pre-College Students and Teachers (SBIR) (R43/R44 Clinical Trial Not Allowed)

 

The purpose of this Notice of Funding Opportunity (NOFO) is to provide support for eligible small business concerns (SBCs) to develop interactive digital media (IDM) biomedical science resources for pre-college students and teachers.

NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed)

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research.

To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on:

NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)

The purpose of this notice of funding opportunity (NOFO) is to provide salary support for exceptional Research Software Engineers (RSEs) that contribute their skills to the development and dissemination of biomedical, behavioral or health related software, tools, and algorithms as well as to the training of prospective users of these tools. 

Building Sustainable Software Tools for Open Science (R03 Clinical Trial Not Allowed)

The purpose of this notice of funding opportunity (NOFO) is to enhance the sustainability and impact of research software tools by enabling the use of best practices and design principles in software development and by leveraging continuing advances in computing. This NOFO is also expected to facilitate the creation of vibrant partnerships between developers and users of software and tools, and to promote FAIR practices for research software to maximize research value. 

Multi-Scale Models Bridging Levels of Analysis in Aging and Alzheimer's Disease (AD) and AD-Related Dementias (ADRD)

This notice of funding opportunity (NOFO) invites applications proposing to establish multi-scale computational models recapitulating dynamic changes associated with aging and Alzheimer’s disease (AD) and AD-related dementias (ADRD). This broad scope encompasses a variety of computational approaches—such as mathematical and computational modeling, image analysis, artificial intelligence, and machine learning—to better understand aging processes and AD/ADRD across molecules, cells and networks, and cognition and behavior. 

BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)

This Brain-Behavior Quantification and Synchronization notice of funding opportunity (NOFO) seeks applications proposing research aiming to 1) develop, validate, and apply cutting-edge tools and methods for minimally invasive, multi-dimensional, high-resolution measurement of behavior at the organismal level, with synchronous capture of changes in the organisms social or physical environment; and 2) develop computational methods that allow for integration of multidimensional behavioral and environmental data representing multiple timescales into a conceptual and/or computational model of be

BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trial Optional)

This Brain-Behavior Quantification and Synchronization notice of funding opportunity (NOFO) seeks applications that bring together transdisciplinary teams and aim to 1) develop, validate, and apply cutting-edge tools and methods for minimally invasive, multi-dimensional, high-resolution objective measurement of behavior at the organismal level, with synchronous capture of dynamic environmental data; 2) develop advanced analytic approaches to integrate multidimensional behavioral, neural and environmental data; and 3) develop and test new theoretical and computational models aiming to advanc