Funded Projects

Funded Projects

MSM Funded projects

Coronary Blood Flow: Integrated Theory and Experiments

Key Personnel: Brian Carlson
Grant No.:
5 U01 HL118738 06
Project collaborators:
Johnathan Tune, Ghassan Kassab

MODELLING THE GROWTH OF THE MIC NICHE AT THE SYSTEM LEVEL

Key Personnel: Zhiwei Ji
Grant No.:
U01 CA166886
Project collaborators:

Predictive multiscale in silico cardio-pharmacology

PI: Colleen Clancy
Grant No.:
U01 HL126273
Project collaborators:

Sensorimotor processing, decision making, and internal states: towards a realistic multiscale circuit model of the larval zebrafish brain)., N/A, N/A

PI: Florian Engert
Grant No.:
19NS104653
Project collaborators:
PI: Florian Engert
Grant No.:
na
Project collaborators:
PI: Florian Engert
Grant No.:
na
Project collaborators:

Theories, Models and Methods for Analysis of Complex Data from the Brain

PI: Moo Chung
Grant No.:
BRAINR01EB022856
Project collaborators:

1R01EB026939 A UNIFIED FRAMEWORK TO STUDY HISTORY DEPENDENCE IN THE NERVOUS SYSTEM , N/a

PI: Fidel Santamaria
Grant No.:
1R01EB026939
Project collaborators:
PI: Fidel Santamaria
Grant No.:
1R01EB026939
Project collaborators:

A Brain Circuit Program for Understanding the Sensorimotor Basis of Behavior, Dissecting distributed representations by advanced population activity analysis methods and modeling

PI: Shaul Druckmann
Grant No.:
NS104655
Project collaborators:
PI: Shaul Druckmann
Grant No.:
EB028171
Project collaborators:
PI: Shaul Druckmann
Grant No.:
EB028171
Project collaborators:
PI: Shaul Druckmann
Grant No.:
NS104655
Project collaborators:
PI: Shaul Druckmann
Grant No.:
EB028171
Project collaborators:
PI: Shaul Druckmann
Grant No.:
EB028171
Project collaborators:

A Brain Circuit Program for Understanding the Sensorimotor Basis of Behavior

PI: Michael Dickinson
Grant No.:
BRAINU19NS104655
Project collaborators:

A Lower Extremity Neuromusculoskeletal Human Simulator: Addressing Multiscale Challenges

PI: Kevin Shelburne
Grant No.:
U01AR072989
Project collaborators:
Peter Laz, Paul Rullkoetter, Clare Fitzpatrick, Brad Davidson, Chadd Clary

A multi-scale computational model of the extracellular matrix of the lung

PI: Bela Suki
Grant No.:
HL139466
Project collaborators:
Jason H.T. Bates
PI: Jason Bates
Grant No.:
HL139466
Project collaborators:
Bela Suki, PhD

A multi-scale model to predict outcomes of immunomodulation and drug therapy during TB

PI: Denise Kirschner
Grant No.:
R01EB012579
Project collaborators:
JoAnne Flynn, Jennifer Linderman

A Multi-Scale Modeling Construct of Knee Mechanics following ACL Reconstruction

PI: Darryl Thelen
Grant No.:
R01AR056201
Project collaborators:
Yasin Dhaher, PhD

Agent-based Models to address the Crisis of Reproducibility and Precision Medicine.

PI: Gary An
Grant No.:
UO1EB025825
Project collaborators:
Chase Cockrell, Daniel Faissol

Agent-based models, the Crisis of Reproducibility and Precision Medicine

PI: daniel faissol
Grant No.:
U01EB025825
Project collaborators:

An integrative statistics-guided image-based multi-scale lung model

PI: Ching-Long Lin
Grant No.:
5U01HL11449402
Project collaborators:
Drs. Kung-Sik Chan, Kun Chen, Eric A. Hoffman, John Newell, Pengwen Chen

Graph theoretical analysis of the effect of brain tumors on functional MRI networks (on NCE until June 2021), Application of the principle of symmetry to neural circuitry: from building blocks to neural synchronization in the connectome

PI: Hernan Makse
Grant No.:
BRAINTMMR01EB022720
Project collaborators:
Manuel Zimmer, University of Vienna
PI: Hernan Makse
Grant No.:
BRAINTMMR01EB028157
Project collaborators:
Manuel Zimmer, University of Vienna
PI: Hernan Makse
Grant No.:
BRAINTMMR01EB022720
Project collaborators:
Manuel Zimmer, University of Vienna
PI: Hernan Makse
Grant No.:
BRAINTMMR01EB028157
Project collaborators:
Manuel Zimmer, University of Vienna

Bayesian Estimation of Network Connectivity and Motifs

Trainee: Martin Bertran
Grant No.:
1R01EB022915
Project collaborators:
Guillermo Sapiro, Dario Ringach, David Dunson, Natalia Martinez, Ye Wang

Beyond Diagnostic Classification of Autism: Neuroanatomical, Functional, and Behavioral Phenotypes

PI: Bei Phillips
Grant No.:
EB022876
Project collaborators:

BIGDATA: Modeling Simulation and Visualization for Medical Device Design

PI: Daniel Keefe
Grant No.:
1R01EB018205
Project collaborators:
Arthur Erdman

Biomedical Simulations Resource

PI: David D'Argenio
Grant No.:
P41 EB001978
Project collaborators:
PI: Vasilis Marmarelis
Grant No.:
N/A
Project collaborators:
David D'Argenio, Ted Berger, Michael Khoo

Biosimulation of Surgical Vocal Fold Injury

PI: Nicole Yee-Key Li-Jessen
Grant No.:
R03DC012112
Project collaborators:

Boundary Element Fast Multipole Method on MATLAB Platform

PI: Sergey Makarov
Grant No.:
MASNM1920
Project collaborators:
None

Bridging multiple scales in modeling targeted drug nanocarrier delivery

PI: Ravi Radhakrishnan
Grant No.:
NIHU01EB016027
Project collaborators:

Bridging Multiple Scales in Modeling Targeted Drug Nanocarrier Delivery

PI: Portonovo Ayyaswamy
Grant No.:
U01 EB016027
Project collaborators:
David M. Eckmann, Ravi Radhakrishnan

Building analysis tools and a theory framework for inferring principles of neural computation from multi-scale organization in brain recordings

PI: Friedrich Sommer
Grant No.:
1R01EB026955
Project collaborators:

BUILDING MULTILEVEL MODELS OF THERAPEUTIC RESPONSE IN THE LUNGS

PI: Tim Corcoran
Grant No.:
1U01HL131046-01
Project collaborators:

Building Multilevel Models of Therapeutic Response in the Lungs

PI: Robert Parker
Grant No.:
1U01HL131046-01
Project collaborators:
Timothy E. Corcoran

Cardiac Energy Grid

PI: James Bassingthwaighte
Grant No.:
R01 HL122199
Project collaborators:
H Sauro, Dan Beard, Andrew McCulloch, Ranjan Dash, Michael Regnier

CAREER: Multiscale Modeling of a Virtual Kidney during the Onset and Progression of Diabetic Kidney Disease

PI: Ashlee Ford Versypt
Grant No.:
NSF 1845117
Project collaborators:

Center for Integrative Biomedical Engineering, Integration of Uncertainty Quantification with the SCIRun Bioelectric Field Simulation Pipeline

PI: Rob MacLeod
Grant No.:
P41GM103545
Project collaborators:
Chris Johnson, Ross Whitaker, and Dana Brooks, Akil Narayan
PI: Rob MacLeod
Grant No.:
U24EB029012
Project collaborators:
Chris Johnson, Ross Whitaker, and Dana Brooks, Akil Narayan
PI: Rob MacLeod
Grant No.:
P41GM103545
Project collaborators:
Chris Johnson, Ross Whitaker, and Dana Brooks, Akil Narayan
PI: Rob MacLeod
Grant No.:
U24EB029012
Project collaborators:
Chris Johnson, Ross Whitaker, and Dana Brooks, Akil Narayan

Central Mechanisms of Airway Protection

PI: Donald Bolser
Grant No.:
HL103415
Project collaborators:
Kendall Morris

Clinical Data Intelligence & Advanced Analytics to Reduce Drug Diversion across the Care Delivery Cycle and Drug Supply Chain in Health Systems

PI: Tom Knight
Grant No.:
1R44DA044083-01
Project collaborators:

Competing Segment: Models to Predict Protein Biomaterials Performance

Key Personnel: Chi-Hua Yu
Grant No.:
HH4977
Project collaborators:

Competitive Renewal of Development, Improvement and Extension of the Tissue Simulation Environment - CompuCell3D

Key Personnel: Andy Somogyi
Grant No.:
R01GM122424
Project collaborators:

Computational and circuit mechanisms underlying motor control

Key Personnel: Rajendra Bose
Grant No.:
NS104649-01
Project collaborators:

Computational and Circuit Mechanisms Underlying Rapid Learning, Computational and Circuit Mechanisms Underlying Rapid Learning

Key Personnel: Ariel Rokem
Grant No.:
BRAINU19NS107609
Project collaborators:
Key Personnel: Ariel Rokem
Grant No.:
BRAINU19NS107609
Project collaborators:
Key Personnel: Ariel Rokem
Grant No.:
BRAINU19NS107609
Project collaborators:
Key Personnel: Ariel Rokem
Grant No.:
BRAINU19NS107609
Project collaborators:

Connecting neural circuit architecture and experience-driven probabilistic computations, N/A

PI: Zachary Kilpatrick
Grant No.:
BRAINTMMR01EB029847
Project collaborators:
Josh Gold, University of Pennsylvania, Tim Buschman, Princeton University, Paul Bays, University of Cambridge
PI: Zachary Kilpatrick
Grant No.:
NA
Project collaborators:
Josh Gold, University of Pennsylvania, Tim Buschman, Princeton University, Paul Bays, University of Cambridge

Constitutive and Agent Based Multiscale Models to Improve Vein Graft Survival

PI: Roger TRAN-SON-TAY
Grant No.:
1U01HL119178-01
Project collaborators:
Scott Berceli, Marc Garbey, and Rongling Wu

Constitutive and Agent-Based Multiscale Models to Improve Vein Graft Survival

PI: Scott Berceli
Grant No.:
1U01HL119178
Project collaborators:
Marc Garbey, Rongling Wu, Roger Tran-Son-Tay

Controlling the Mechanobiology of Cutaneous Wounds to Reduce Hypertrophic Scar

PI: Ed Sander
Grant No.:
AR063867
Project collaborators:

Cracking the Olfactory Code

PI: Rick Gerkin
Grant No.:
U19NS112953
Project collaborators:

CRCNS: Improving Bioelectronic Selectivity with Intrafascicular Stimulation

PI: James Abbas
Grant No.:
NIH R01 EB027584
Project collaborators:
Ranu Jung

Cross-scale interactions between mineral and collagen for tendon-bone attachment

PI: Guy Genin
Grant No.:
U01EB01642201A1
Project collaborators:
Markus Buehler, Ioannis Chasiotis, Pedro Ponte Castañeda, Stavros Thomopoulos
PI: Markus Buehler
Grant No.:
U01EB016422
Project collaborators:
Ioannis Chasiotis, David Kaplan, Guy Genin, Pedro Ponte Casteñada, Stavros Thomopolous, Joyce Wong
PI: Stavros Thomopoulos
Grant No.:
U01EB016422-01A1
Project collaborators:
Markus Buehler, Ioannis Chasiotis, Guy Genin, Pedro Ponte Casteneda
Key Personnel: Ioannis Chasiotis
Grant No.:
U01EB016422-01A1
Project collaborators:
Markus Buehler, Guy Genin, Pedro Ponte Casteñada, Stavros Thomopoulos
Key Personnel: Pedro Ponte Casteneda
Grant No.:
U01EB016422-01A1
Project collaborators:
Markus Buehler, Ioannis Chasiotis, Guy Genin, Stavros Thomopoulos

Crossing space and time: uncovering the nonlinear dynamics of multimodal and multiscale brain activity

PI: Shella Keilholz
Grant No.:
Project collaborators:

Data-driven analysis for neuronal dynamic modeling

PI: Gal Mishne
Grant No.:
R01EB026936
Project collaborators:

Developing MSM Methodologies

PI: Terence Sanger
Grant No.:
EB021921
Project collaborators:
Simon Giszter

Dissemination of libRoadRunner and CompuCell3D, Development and Improvement of the Tissue Simulation Toolkit

PI: James Glazier
Grant No.:
U24EB028887
Project collaborators:
PI: James Glazier
Grant No.:
R01GM122424
Project collaborators:
PI: James Glazier
Grant No.:
U24EB028887
Project collaborators:
PI: James Glazier
Grant No.:
R01GM122424
Project collaborators:

Development of a Multiscale Mechanistic Simulation of Acetaminophen Induced Liver Damage

Key Personnel: Jim Sluka
Grant No.:
U01GM111243
Project collaborators:
Glazier, dunn, Klaunig

Diagnosis of Alzheimers Disease Using Dynamic High-Order Brain Networks

Key Personnel: Han Zhang
Grant No.:
BRAINR01EB022880
Project collaborators:
Key Personnel: Zhen Zhou
Grant No.:
BRAINR01EB022880
Project collaborators:
PI: Pew-Thian Yap
Grant No.:
EB022880
Project collaborators:

Discovering dynamic computations in large-scale neural activity recordings

PI: Tatiana Engel
Grant No.:
BRAINR01EB026949
Project collaborators:
A. Churchland, K. Shenoy

Dissemination of a tool for data-driven multiscale modeling of brain circuits

PI: Salvador Dura-Bernal
Grant No.:
U24 EB028998-01
Project collaborators:

Don't have one just want to participate and make connections

PI: Tarynn Witten
Grant No.:
my invite email expired before I could respond
Project collaborators:

Efficient resource allocation and information retention in working memory circuits

PI: ShiNung Ching
Grant No.:
EB028154
Project collaborators:
Lawrence Snyder
PI: lawrence snyder
Grant No.:
R01EB028154
Project collaborators:
ShiNung Ching

Embedded Ensemble Encoding

Key Personnel: Sergio Angulo
Grant No.:
EB02290301
Project collaborators:
PI: Srdjan Antic
Grant No.:
EB29633330
Project collaborators:
William Lytton

Extension of NEURON simulator for simulation of reaction-diffusion in neurons, Microconnectomics of neocortex: a multiscale computer model, Embedded Ensemble Encoding, Microconnectomics of neocortex: a multiscale computer model, SPARC: Modeling network dynamics of cardiac right atrial ganglionic plexus to enable in silico testing of vagal neurostimulation strategies

PI: William Lytton
Grant No.:
R01MH086638
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01EB022903
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01MH086638
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01EB022903
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01MH086638
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01EB022903
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01MH086638
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01EB022903
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal

Emergent dynamics from network connectivity: a minimal model

Key Personnel: Katherine Morrison
Grant No.:
BRAINEB022862
Project collaborators:

Executive committee member

Trainee: Bruno Rego
Grant No.:
NA
Project collaborators:

EXTENSION OF NEURON SIMULATOR FOR SIMULATION OF REACTION-DIFFUSION IN NEURONS

Key Personnel: Adam Newton
Grant No.:
5R01MH086638
Project collaborators:

FEBio: Finite Elements for Biomechanics and Biophysics

PI: Jeff Weiss
Grant No.:
R01GM083925
Project collaborators:

Filtered Point Process Inference Framework for Modeling Neural Data

PI: Emery Brown
Grant No.:
5R01EB022726
Project collaborators:
Mriganka Sur, MIT, Wasim Malik, MGH

Human Neocortical Neurosolver

PI: Stephanie Jones
Grant No.:
EB022889
Project collaborators:

Image Driven Multi-Scale Modeling to Predict Treatment Response in Breast Cancer

Other: Erin Rericha
Grant No.:
1U01 CA174706-01
Project collaborators:
Tom Yankeelov, Vito Quaranta, Mike Miga
Key Personnel: Darren Tyson
Grant No.:
1U01CA174706
Project collaborators:
PI: Thomas Yankeelov
Grant No.:
U01CA174706
Project collaborators:

Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary Hypertension

PI: C. Alberto Figueroa
Grant No.:
U01HL135842
Project collaborators:
PI: Carlos Figueroa
Grant No.:
U01HL135842
Project collaborators:
PI: Seungik Baek
Grant No.:
1U01HL135842
Project collaborators:
Alberto Figueroa

Infarct-related Ventricular Tachycardia Mechanisms: From Micro to Clinical, Simulation guidance of ablation therapy for persistent atrial fibrillation

PI: Natalia Trayanova
Grant No.:
U01HL141074
Project collaborators:
PI: Natalia Trayanova
Grant No.:
U01HL141074
Project collaborators:

Integrating Bioinformatics into Multiscale Models for Hepatocellular Carcinoma

Key Personnel: Lyla Atta
Grant No.:
1U01CA212007-01A1
Project collaborators:
Key Personnel: Emma Bigelow
Grant No.:
n/a
Project collaborators:
Elana Fertig
Key Personnel: Archana Balan
Grant No.:
U01
Project collaborators:

Integrating bioinformatics into multiscale models for hepatocellular carcinoma

Key Personnel: Richard Sové
Grant No.:
U01CA212007
Project collaborators:
Elana Fertig, Aleksander Popel, Phuoc Tran, Andrew Ewald

Integrating bioinformatics into multiscale models for hepatocellular carcinoma

PI: Elana Fertig
Grant No.:
U01CA212007
Project collaborators:
Aleksander Popel, Phuoc Tran, Andrew Ewald
PI: Phuoc Tran
Grant No.:
1U01CA212007
Project collaborators:
Andrew Josef Ewald, PHD; Elana Judith Fertig (contact), PHD; ALEKSANDER S. POPEL, PhD

Integration of Uncertainty Quantification with the SCIRun Bioelectric Field Simulation Pipeline

Other: Dana Brooks
Grant No.:
U24EB029012
Project collaborators:
Akil Narayan, Rob MacLeod
Other: Lindsay Rupp
Grant No.:
U24EB029012
Project collaborators:
Rob MacLeod, Akil Narayan, Chris Johnson, and Dana Brooks, Ross Whitaker
Other: Zexin Liu
Grant No.:
U24EB029012
Project collaborators:
Chris Johnson, Ross Whitaker, Akil Narayan, and Dana Brooks
Key Personnel: Akil Narayan
Grant No.:
U24EB029012
Project collaborators:
and Dana Brooks, Rob MacLeod

Integration of Uncertainty Quantification with the SCIRun Bioelectric Field Simulation Pipeline


Other: Sumientra Rampersad
Grant No.:
U24EB029012
Project collaborators:
Chris Johnson, Ross Whitaker, Akil Narayan, and Dana Brooks, Rob MacLeod

Invasive Approach to Model Human Cortex-Basal Ganglia Action-Regulating Networks

PI: Vasileios Christopoulos
Grant No.:
1U01NS09896101
Project collaborators:

Large-scale Network Modeling for Brain Dynamics: Statistical Learning and Optimization

PI: Xi Luo
Grant No.:
R01EB022911
Project collaborators:

Learning spatio-temporal statistics from the environment in recurrent networks

PI: Nicolas Brunel
Grant No.:
EB022891
Project collaborators:
Harel Shouval

MANIFOLD-VALUED STATISTICAL MODELS FOR LONGITUDINAL MORPHOMETIC ANALYSIS IN PRECLINICAL ALZHEIMER'S DISEASE (AD)

PI: Vikas Singh
Grant No.:
R01EB022883
Project collaborators:

Mathematical modeling of the dynamics of Covid-19 pandemic

PI: Gilberto Gonzalez-Parra
Grant No.:
Project collaborators:

MEASURING, MODELING, AND MODULATING CROSS-FREQUENCY COUPLING

PI: Mark Kramer
Grant No.:
R01EB026938
Project collaborators:
Alik Widge, Uri Eden

Mechanisms of neural circuit dynamics in working memory and decision-making

Key Personnel: Manuel Schottdorf
Grant No.:
5U19NS104648
Project collaborators:

Mental, measurement, and model complexity in neuroscience

PI: Joshua Gold
Grant No.:
EB026945
Project collaborators:
Vijay Balasubramanian

Micro-Temporal Proesses Underlying Health Behavior Adoption and Maintenance (microT Study)

PI: Stephen Intille
Grant No.:
1U01HL146327
Project collaborators:

Microtemporal Processes Underlying Health Behavior Adoption and Maintenance

PI: Genevieve Dunton
Grant No.:
U01HL146327
Project collaborators:

Model for Platelet Adhesion and Thrombus Formation

PI: Michael King
Grant No.:
HL097971
Project collaborators:

Modeling and analysis of material transport in complex geometry of neurons

PI: Jessica Zhang
Grant No.:
NSF-CBET 1804929
Project collaborators:

Modeling bi-directional signaling and cytoskeletal dynamics in 3D cell migrations

PI: Roger Kamm
Grant No.:
1U01CA177799-01
Project collaborators:
Muhammad Zaman, Douglas Lauffenburger, Frank Gertler

MODELING BI-DIRECTIONAL SIGNALING AND CYTOSKELETAL DYNAMICS IN 3D CELL MIGRATIONS

PI: Muhammad Zaman
Grant No.:
5U01CA177799
Project collaborators:

Modeling Brainstem Inflammation's Role in Systemic Dysfunction during Sepsis

PI: Thomas E. Dick
Grant No.:
U01 EB021960-01A1
Project collaborators:
Kenneth A Loparo, Frank J. Jacono, Yoram Vodovotz, Yaroslav Molkov, Yee-Hsee Hsieh

MODELING BRAINSTEM INFLAMMATION'S ROLE IN SYSTEMIC MODELING BRAINSTEM INFLAMMATION'S ROLE IN SYSTEMIC

Key Personnel: William Barnett
Grant No.:
U01 EB 021960
Project collaborators:

Modeling multi-area dynamics during motor control

Key Personnel: Larry Abbott
Grant No.:
1U19NS104649-01
Project collaborators:

Modeling Multiscale Control of Liver Regeneration

PI: Rajanikanth Vadigepalli
Grant No.:
EB023224
Project collaborators:

Modeling the Role of Brainstem Inflammation in Systemic Dysfunction during Sepsis.

Key Personnel: Frank Jacono
Grant No.:
1U01EB021960-01A1
Project collaborators:
Thomas E. Dick, Kenneth A. Loparo, Yoram Vodovotz, Yaroslav Molkov

Modeling the structure-function relation in a reconstructed cortical tissue, N/A

PI: Stefan Mihalas
Grant No.:
EB029813
Project collaborators:
Anton Arkhipov
PI: Stefan Mihalas
Grant No.:
NA
Project collaborators:
Anton Arkhipov

Modeling the structure-function relation in a reconstructed cortical tissue

PI: Anton Arkhipov
Grant No.:
1R01EB029813
Project collaborators:

MODELLING THE GROWTH OF THE MIC NICHE AT THE SYSTEM LEVEL

Key Personnel: Jing Su
Grant No.:
5U01CA166886-03
Project collaborators:

Models and methods for calcium imaging data, with application to the Allen Brain Observatory

PI: Daniela Witten
Grant No.:
5R01EB026908
Project collaborators:
Michael Buice

Models to Predict Protein Biomaterial Performance

Key Personnel: Davoud Ebrahimi
Grant No.:
U01 EB014976
Project collaborators:
PI: David Kaplan
Grant No.:
U01EB014976
Project collaborators:
Markus Buehler (MIT), Joyce Wong (BU)

Models to predict protein biomedical performance

PI: Joyce Wong
Grant No.:
U01 EB014976
Project collaborators:

Modular design of multiscale models, with an application to the innate immune response to fungal respiratory pathogens

PI: Reinhard Laubenbacher
Grant No.:
1U01EB02450101
Project collaborators:
Key Personnel: Joseph Masison
Grant No.:
1U01EB024501
Project collaborators:

Modular design of multiscale models, with an application to the innate immune response to fungal respiratory pathogens.

Other: Bruce Shapiro
Grant No.:
U01EB024501
Project collaborators:

MSM proposal currently in review

PI: Silvia Blemker
Grant No.:
NA
Project collaborators:

Multi-region 'Network of Networks' Recurrent Neural Network Models of Adaptive and Maladaptive Learning

PI: Kanaka Rajan
Grant No.:
1R01EB02816601
Project collaborators:
Karl Deisseroth - Stanford University; Kafui Dzirasa - Duke University; Peter Rudebeck - Mount Sinai; Helen Mayberg - Mount Sinai

Multi-Scale Laws of Myocardial Growth and Remodeling

PI: Ellen Kuhl
Grant No.:
U01-HL119578
Project collaborators:
PI: julius guccione
Grant No.:
U01HL119578
Project collaborators:

Multi-scale modeling of gas transport through channels in living cells

Key Personnel: Ahmad Raeisi Najafi
Grant No.:
U01-GM111251
Project collaborators:

Multi-scale modeling of genetic variation in a developmental network

Other: Paul Marjoram
Grant No.:
1U01GM103804
Project collaborators:
Nuzhdin, De Pace, Rohs
PI: Angela DePace
Grant No.:
1 U01 GM103804-01A1
Project collaborators:
Sergey Nuzhdin, Remo Rohs, Paul Marjoram

Multi-scale modeling of influenza vaccination strategies for optimal T cell immunity

PI: Veronika Zarnitsyna
Grant No.:
U01HL139483
Project collaborators:

Multi-Scale Modeling to Predict Long-Term Growth and Remodeling of Skin in Response to Stretch

PI: Adrian Buganza Tepole
Grant No.:
R01AR074525
Project collaborators:

MULTIMODALITY IMAGING-DRIVEN MULTIFIDELITY MODELING OF AORTIC DISSECTION

Key Personnel: Minglang Yin
Grant No.:
U01HL142518
Project collaborators:

Multiscale . Model of the vagal outflow to the heart

PI: james schwaber
Grant No.:
UO1HL133360
Project collaborators:
Rajanikanth Vadigepalli

Multiscale Analysis of Trauma

Key Personnel: Evan Tsiklidis
Grant No.:
U01-HL-131053
Project collaborators:
PI: Scott Diamond
Grant No.:
131053
Project collaborators:
Talid Sinno, Carrie Sims, Lawrence Brass, Yannis Kevrekidis

Multiscale modeling and empirical study of a mechanism limiting blood clot growth

PI: Mark Alber
Grant No.:
1U01HL116330
Project collaborators:
Dr. John Weisel, University of Pennsylvania School of Medicine

Multiscale modeling and empirical study of a mechanism limiting blood clot growth.

Key Personnel: Zhiliang Xu
Grant No.:
NIH: IU01HL116330-01A1
Project collaborators:
Mark Alber, Rustem Litvinov, John Weisel

Multiscale Modeling for Treatment discovery in Duchenne Muscular Dystrophy

PI: Shayn Peirce-Cottler
Grant No.:
U01AR06939301
Project collaborators:
Silvia Blemker

Multiscale Modeling of Blood Flow and Platelet Mediated Thrombosis

PI: Danny Bluestein
Grant No.:
5U01HL131052
Project collaborators:
Yuefan Deng, Marvin J Slepian

Multiscale Modeling of Bone Environment Responses to Metastatic Prostate Cancer

PI: David Basanta
Grant No.:
U01CA202958
Project collaborators:

Multiscale Modeling of Bone Environment Responses to Metastatic Prostate Cancer

PI: Conor Lynch
Grant No.:
U01CA202958
Project collaborators:

Multiscale modeling of cerebral blood flow and oxygen transport

PI: Timothy Secomb
Grant No.:
U01 HL133362
Project collaborators:
Sava Sakadzic, David Boas

Multiscale Modeling of Circadian Rhthyms

PI: William (Bill) Cannon
Grant No.:
1U01EB02254601
Project collaborators:
Jay Dunlap, Dartmouth; Jennifer Hurley, RPI

Multiscale Modeling of Circadian Rhythms

Key Personnel: Samuel Britton
Grant No.:
U01EB022546
Project collaborators:
William Cannon, Jay Dunlap, Jennifer Hurley, Mark Alber

Multiscale Modeling of Clotting Risk in Atrial Fibrillation

PI: Boyce Griffith
Grant No.:
U01HL143336
Project collaborators:

Multiscale Modeling of Gas Transport Through Channels in Living Cells

Key Personnel: Paween Mahinthichaichan
Grant No.:
U01-GM111251
Project collaborators:

MULTISCALE MODELING OF INFLUENZA VACCINATION STRATEGIES FOR OPTIMAL T CELL IMMUNITY

Key Personnel: Zheng-Rong Li
Grant No.:
U01HL139483
Project collaborators:

Multiscale modeling of influenza vaccination strategies for optimal T cell immunity

PI: Jacob Kohlmeier
Grant No.:
HL139483
Project collaborators:
Veronika Zarnitsyna

Multiscale modeling of inherited cardiomyopathies and therapeutic interventions

PI: Jonathan Wenk
Grant No.:
U01HL133359
Project collaborators:
PI: Kenneth Campbell
Grant No.:
HL133359
Project collaborators:

Multiscale Modeling of Lung Disease-Influenced Aerosol Dosimetry

Key Personnel: Andrew Kuprat
Grant No.:
1U01ES028669-01A1
Project collaborators:
Chantal Darquenne, Richard Corley, Bahman Asgharian
PI: Chantal Darquenne
Grant No.:
1 U01 ES028669-01A1
Project collaborators:

Multiscale modeling of metabolic and regulatory networks

Key Personnel: Neeraj Kumar
Grant No.:
N/A
Project collaborators:
William Cannon

Multiscale Modeling of Sickle Cell Anemia: Methods and Validation

PI: George Karniadakis
Grant No.:
U01HL11447601
Project collaborators:
MIT (Ming Dao), MGH (John Higgins), U Houston (Peter Vekilov)

Multiscale Modeling of Sickle Cell Anemia: Methods and Validation

PI: Ming Dao
Grant No.:
U01HL114476
Project collaborators:
George Karniadakis
Key Personnel: Xuejin Li
Grant No.:
U01HL114476
Project collaborators:

Multiscale modeling of the cocktail party problem

PI: Mounya Elhilali
Grant No.:
U01AG058532
Project collaborators:

Multiscale modeling of the failing heart for cardiac resynchronization therapy

PI: Andrew McCulloch
Grant No.:
1R01HL096544
Project collaborators:
David Krummen, Jeffrey Omens

Multiscale Modeling of the Mammalian Circadian Clock: The Role of GABA Signaling

PI: Michael Henson
Grant No.:
U01 EB021956-01
Project collaborators:

Multiscale modeling of the mammalian circadian clock: The Role of GABA Signaling

PI: Erik Herzog
Grant No.:
U01EB021956
Project collaborators:
Michael Henson and Yannis Kevrekidis

Multiscale Modeling of Wound Healing

PI: Jason Haugh
Grant No.:
U01EB018816
Project collaborators:
James Bear (UNC-Chapel Hill), Timothy Elston (UNC-Chapel Hill)

Multiscale modeling to map cardiac electrophysiology between species

PI: Eric Sobie
Grant No.:
U01 HL 136297
Project collaborators:
David Christini
PI: David Christini
Grant No.:
U01HL136297
Project collaborators:
Eric Sobie

Multiscale Models of Cardiac Growth, Remodeling, and Myocardial Infarction

PI: Jeff Holmes
Grant No.:
U01 HL-120862
Project collaborators:

MULTISCALE MODELS OF NEURAL POPULATION CONTROL IN SPINAL CORD

PI: Simon Giszter
Grant No.:
U01 EB021921
Project collaborators:
Terence Sanger
Key Personnel: Simon Giszter
Grant No.:
U01 EB021921
Project collaborators:
Terence D Sanger

Multiscale Models of Wound Cell Plasticity for Regeneration

PI: Qing Nie
Grant No.:
U01AR073159
Project collaborators:

Multiscale Molecular Systems Biology- Reconstruction and Model Optimization

PI: Ronan Fleming
Grant No.:
SC0010429
Project collaborators:
Michael Saunders (Stanford University), Bernhard Palsson (UCSD)

Multiscale Molecular Systems Biology: Reconstruction and Model Optimization

PI: Michael Saunders
Grant No.:
U01GM102098
Project collaborators:
Bernhard Palsson, Ronan Fleming, Ines Thiele

Multiscale Multiphysics Model of Thrombus Biomechanics in Aortic Dissection

PI: Jay Humphrey
Grant No.:
U01HL116323
Project collaborators:
George Karniadakis
PI: Jay Humphrey
Grant No.:
U01 HL116323
Project collaborators:
George Karniadakis

Multiscale spatiotemporal modeling of cardiac mitochondria

PI: Mohsin Jafri
Grant No.:
1U01HL116321-01A1
Project collaborators:
PHD William Jonathan Lederer (contact), MD CARMEN A. MANNELLA
PI: W. Jonathan Lederer
Grant No.:
1U01HL116321
Project collaborators:
MOHSIN Saleet JAFRI, PHD William Jonathan Lederer (contact), MD CARMEN A. MANNELLA, PhD

Multiscale, Transport-Dependent NO Signaling: Cells to Vascular Networks

Key Personnel: Kenneth Barbee
Grant No.:
1U01HL116256-01A1
Project collaborators:
Dov Jaron, Donald Buerk

Multiscale, Transport-Dependent NO Signalling: Cells to Vascular Networks

Key Personnel: Donald Buerk
Grant No.:
U01 HL116256
Project collaborators:
Dov Jaron, Ken Barbee

N/A (from NCI CSBC program)

PI: Aaron Meyer
Grant No.:
N/A
Project collaborators:

N/A (Working with OpenSim in BioMch working group)

Key Personnel: Jacqueline Tran
Grant No.:
N/A (Working with OpenSim in BioMch working group)
Project collaborators:

National Resource for Cell Analysis and Modeling

PI: Leslie Loew
Grant No.:
P41GM103313
Project collaborators:

Neural Basis of Causal Inference

PI: Jan Drugowitsch
Grant No.:
U19NS118246
Project collaborators:

Neuronal population dynamics within and across cortical areas

PI: Matthew Smith
Grant No.:
EB026953
Project collaborators:
PI: Byron Yu
Grant No.:
BRAINR01EB026953
Project collaborators:
Doiron, Brent, Smith, Matthew

New methods and theories to interrogate organizational principles from single cell to neuronal networks

PI: Mara Dierssen
Grant No.:
TMMEB28159
Project collaborators:
Key Personnel: Linus Manubens-Gil
Grant No.:
BRAINR01EB028159
Project collaborators:
PI: Bing Ye
Grant No.:
1R01EB028159
Project collaborators:
Mara Dierssen

NIAMS: CORT Innovations to Assess and Forestall Post-Traumatic Osteoarthritis

Key Personnel: Bruce Ayati
Grant No.:
1 p50 AR055533
Project collaborators:
James Martin, Joseph Buckwalter

NIH - Age Dependent Mecahnical Ventilator induced Inflammation: Modeling and Experiments

PI: Ramana Pidaparti
Grant No.:
NIH (R01AG041823)
Project collaborators:
Angela Reynolds and Rebecca Heise

NIH MIDAS and DTRA CNIMS

PI: Madhav Marathe
Grant No.:
Dont remember
Project collaborators:

No project title

Key Personnel: Blanca Pineda
Grant No.:
No grant number
Project collaborators:

None

PI: Anahita Akbari
Grant No.:
None
Project collaborators:

NOVEL BAYESIAN LINEAR DYNAMICAL SYSTEMS-BASED METHODS FOR DISCOVERING HUMAN BRAIN CIRCUIT DYNAMICS IN HEALTH AND DISEASE

PI: Vinod Menon
Grant No.:
R01EB022907
Project collaborators:

Operationalizing Behavioral Theory for mHealth: Dynamics, Context, and Personalization

PI: Donna Spruijt-Metz
Grant No.:
U01CA229445
Project collaborators:
Benjamin Marlin, Pedja Klasnja, Misha Pavel, Eric Hekler, Daniel Rivera

OPERATIONALIZING BEHAVIORAL THEORY FOR MHEALTH: DYNAMICS, CONTEXT, AND PERSONALIZATION

PI: Benjamin Marlin
Grant No.:
1 U01 CA229445 01
Project collaborators:
Donna Spruijt-Metz, Predrag Klasnja, Eric Hekler, Daniel Rivera, Misha Pavel

Oxytocin modulation of neural circuit function and behavior

Key Personnel: Alisa Surkis
Grant No.:
U19 NS107616
Project collaborators:

Oxytocin Modulation of Neural Circuit Function and Behavior

PI: Robert Froemke
Grant No.:
NS107616
Project collaborators:
Key Personnel: Luisa Schuster
Grant No.:
1U19NS107616-01
Project collaborators:
Key Personnel: Peter Petersen
Grant No.:
BRAINU19NS107616
Project collaborators:

Peri-procedural transmural electrophysiological imaging of scar-related ventricular tachycardia

PI: Linwei Wang
Grant No.:
R01HL145590-01
Project collaborators:

Predicting Cell Deformation from Body Level Mechanical Loads

PI: Ahmet Erdemir
Grant No.:
R01EB009643
Project collaborators:

Predictive modeling of bioelectric activity on mammalian multilayered neuronal stimulation

PI: Gianluca Lazzi
Grant No.:
U01EB025830
Project collaborators:
Ted Berger
PI: Theodore Berger
Grant No.:
U01GM104604
Project collaborators:
Gianluca Lazzi

Predictive Modeling of Bioelectric Activity on Mammalian Multilayered Neuronal Structures in the Presence of Supraphysiological Electric Fields

Key Personnel: Jean-Marie Bouteiller
Grant No.:
GM104604
Project collaborators:
Gianluca Lazzi, Ted Berger
Key Personnel: Gene Yu
Grant No.:
5U01EB025830
Project collaborators:
PI: Dong Song
Grant No.:
9U01EB025830
Project collaborators:

PREDICTIVE MULTISCALE IN SILICO CARDIO-PHARMACOLOGY

Key Personnel: Igor Vorobyov
Grant No.:
5U01HL126273-03
Project collaborators:
PI: Colleen Clancy
Grant No.:
1U01HL126273-01A1
Project collaborators:
Vladimir Yarov-Yarovoy, Robert D. Harvey

Predictive multiscale in silico cardio-pharmacology

Key Personnel: Parya Aghasafari
Grant No.:
U01HL126273
Project collaborators:

Predictive Multiscale in Silico Cardio-Pharmacology

Key Personnel: Pei-Chi Yang
Grant No.:
5U01HL126273-04
Project collaborators:

Predictive Multiscale Modeling of Microbial Consortia Biofilms

PI: Ross Carlson
Grant No.:
U01EB019416
Project collaborators:

Quantifying Causality for Neuroscience

PI: Konrad Kording
Grant No.:
EB028162
Project collaborators:

Readout and control of spatiotemporal neuronal codes

PI: Wolfgang Losert
Grant No.:
1U19NS107464
Project collaborators:

Real-time Statistical Algorithms for Controlling Neural Dynamics and Behavior

PI: Il Memming Park
Grant No.:
EB026946
Project collaborators:
jonathan pillow, alfredo fontanini, carlos brody

Real-time statistical algorithms for controlling neural dynamics and behavior

PI: Jonathan Pillow
Grant No.:
1R01EB026946
Project collaborators:
Il Memming Park

Recruitment of Dr. Benjamin Fregly, Established Investigator

Key Personnel: Andrew Baines
Grant No.:
RR170026
Project collaborators:

Reproducible Modeling Center

PI: Herbert Sauro
Grant No.:
NA
Project collaborators:
Jonathan Karr, Ion Moraru, David Nickerson, John Gennari

Reverse Engineering the Brain Stem Circuits that Govern Exploratory Behavior

Key Personnel: Yoav Freund
Grant No.:
BRAINNS107466
Project collaborators:

Robust Predictors of Mania and Psychosis

PI: Justin Baker
Grant No.:
U01MH116925
Project collaborators:

Sensorimotor processing, decision making, and internal states: towards a realistic multiscale circuit model of the larval zebrafish brain, N/A

PI: Florian Engert
Grant No.:
5U01NS090449
Project collaborators:
Jeff Lichtman, Haim Sompolinsky
PI: Florian Engert
Grant No.:
NA
Project collaborators:
Jeff Lichtman, Haim Sompolinsky

Sequence Learning in Recurrent Neural Networks

PI: Harel Shouval
Grant No.:
R01EB022891
Project collaborators:
Nicolas Brunel

Simulation guidance of ablation therapy for persistent atrial fibrillation

Key Personnel: Patrick Boyle
Grant No.:
U01-HL-141074
Project collaborators:
Natalia Trayanova, Hugh Calkins, Adityo Prakosa

Software for Practical Annotation and Exchange of Virtual Anatomy

PI: Andinet Enquobahrie
Grant No.:
R01EB025212
Project collaborators:

Spinal Circuits for the Control of Dexterous Movement

Trainee: Graziana Gatto
Grant No.:
1U19NS11295901
Project collaborators:

Stochastic Simulation Service: A Cloud Computing Framework for Modeling and Simulation of Stochastic Biochemical Systems

Key Personnel: Brian Drawert
Grant No.:
R01EB014877
Project collaborators:
Linda Petzold

StochSS: A Next-Generation Toolkit for Simulation-Driven Biological Discovery

PI: Linda Petzold
Grant No.:
2R01EB01487704A1
Project collaborators:
Andreas Hellander; Uppsala University, Brian Drawert; UNC Asheville

Systems Biology of Hypertrophic Heart Disease from Molecular Pathways to Organ System

Key Personnel: Ali Khalilimeybodi
Grant No.:
R01HL137100
Project collaborators:

Systems Modeling Guided Bone Regeneration

PI: Xiaobo Zhou
Grant No.:
1U01AR06939501A1
Project collaborators:
YANG, YUNZHI

Systems Modeling Guided Bone regeneration

PI: Yunzhi Yang
Grant No.:
1U01AR069395
Project collaborators:
Xiaobo Zhou

SYSTEMS PHARMACOLOGY MODEL FOR SPATIAL CONTROL OF CARDIAC FIBROSIS

PI: Jeffrey Saucerman
Grant No.:
5R01HL137755
Project collaborators:
Jeffrey Holmes, Shayn Peirce-Cottler

The Center for Innovation in Intensive Longitudinal Studies (CIILS)

PI: Sy-Miin Chow
Grant No.:
U24 EB026436-01
Project collaborators:
NA

Tools for modeling state-dependent sensory encoding by neural populations across spatial and temporal scales

PI: Stephen David
Grant No.:
BRAINR01EB028155
Project collaborators:

Toward a Theory for Macroscopic Neural Computation Based on Laplace Transform

PI: Marc Howard
Grant No.:
EB022864
Project collaborators:
Michael Hasselmo

Towards a Complete Description of the Circuitry Underlying Sharp Wave-Mediated Memory Replay

Key Personnel: Aaron Milstein
Grant No.:
U19NS104590
Project collaborators:

TOWARDS A COMPLETE DESCRIPTION OF THE CIRCUITRY UNDERLYING SHARP WAVE-MEDIATED MEMORY REPLAY

Other: Ben Dichter
Grant No.:
NS104590
Project collaborators:

Towards a unified framework for dopamine signaling in the striatum

Trainee: Akshay Jaggi
Grant No.:
BRAINU19NS113201
Project collaborators:

Transport Phenomena in the Lymphatic System

PI: James Moore
Grant No.:
U01HL123420
Project collaborators:
David Zawieja
Key Personnel: Michael Moreno
Grant No.:
HL123420
Project collaborators:

U01HL114476

Key Personnel: He Li
Grant No.:
N/A
Project collaborators:

Uncovering Population-Level Cellular Relationships to Behavior via Mesoscale Networks

PI: David Carlson
Grant No.:
BRAINEB026937
Project collaborators:
Guillermo Saprio, Kafui Dzirasa

USC Physical Sciences-Oncology Center

Government Program Official: Sean Hanlon
Grant No.:
U54CA143907
Project collaborators:

VPOP (Virtual Populations for Obesity Prevention)

PI: Bruce Lee
Grant No.:
U01HD086861
Project collaborators:
Other: Sarah Rebbert
Grant No.:
U01HD086861
Project collaborators:

XXXX

Other: Helene Gianviti
Grant No.:
XXXX
Project collaborators:

 Operationalizing Behavioral Theory for mHealth: Dynamics, Context, and Personalization

Key Personnel: Misha Pavel
Grant No.:
1U01CA229445-01
Project collaborators:

“Integrating Bioinformatics into Multiscale Models for Hepatocellular Carcinoma”

Key Personnel: Gaurav Sharma
Grant No.:
U01CA212007
Project collaborators: