Funded Projects

Funded Projects

MSM Funded projects

Coronary Blood Flow: Integrated Theory and Experiments

Key Personnel: Brian Carlson
Grant No.:
5 U01 HL118738 06
Project collaborators:
Johnathan Tune, Ghassan Kassab

MODELLING THE GROWTH OF THE MIC NICHE AT THE SYSTEM LEVEL

Key Personnel: Zhiwei Ji
Grant No.:
U01 CA166886
Project collaborators:

Predictive multiscale in silico cardio-pharmacology

PI: Colleen Clancy
Grant No.:
U01 HL126273
Project collaborators:

Theories, Models and Methods for Analysis of Complex Data from the Brain

PI: Moo Chung
Grant No.:
BRAINR01EB022856
Project collaborators:

1R01EB026939 A UNIFIED FRAMEWORK TO STUDY HISTORY DEPENDENCE IN THE NERVOUS SYSTEM

PI: Fidel Santamaria
Grant No.:
1R01EB026939
Project collaborators:

A Brain Circuit Program for Understanding the Sensorimotor Basis of Behavior

PI: Shaul Druckmann
Grant No.:
NS104655
Project collaborators:
PI: Shaul Druckmann
Grant No.:
EB028171
Project collaborators:
PI: Michael Dickinson
Grant No.:
BRAINU19NS104655
Project collaborators:

A Lower Extremity Neuromusculoskeletal Human Simulator: Addressing Multiscale Challenges

PI: Kevin Shelburne
Grant No.:
U01AR072989
Project collaborators:
Peter Laz, Paul Rullkoetter, Clare Fitzpatrick, Brad Davidson, Chadd Clary

A multi-scale computational model of the extracellular matrix of the lung

PI: Bela Suki
Grant No.:
HL139466
Project collaborators:
Jason H.T. Bates
PI: Jason Bates
Grant No.:
HL139466
Project collaborators:
Bela Suki, PhD

A multi-scale model to predict outcomes of immunomodulation and drug therapy during TB

PI: Denise Kirschner
Grant No.:
R01EB012579
Project collaborators:
JoAnne Flynn, Jennifer Linderman

A Multi-Scale Modeling Construct of Knee Mechanics following ACL Reconstruction

PI: Darryl Thelen
Grant No.:
R01AR056201
Project collaborators:
Yasin Dhaher, PhD

Agent-based Models to address the Crisis of Reproducibility and Precision Medicine.

PI: Gary An
Grant No.:
UO1EB025825
Project collaborators:
Chase Cockrell, Daniel Faissol

Agent-based models, the Crisis of Reproducibility and Precision Medicine

PI: daniel faissol
Grant No.:
U01EB025825
Project collaborators:

An integrative statistics-guided image-based multi-scale lung model

PI: Ching-Long Lin
Grant No.:
5U01HL11449402
Project collaborators:
Drs. Kung-Sik Chan, Kun Chen, Eric A. Hoffman, John Newell, Pengwen Chen

Bayesian Estimation of Network Connectivity and Motifs

Trainee: Martin Bertran
Grant No.:
1R01EB022915
Project collaborators:
Guillermo Sapiro, Dario Ringach, David Dunson, Natalia Martinez, Ye Wang

Beyond Diagnostic Classification of Autism: Neuroanatomical, Functional, and Behavioral Phenotypes

PI: Bei Phillips
Grant No.:
EB022876
Project collaborators:

BIGDATA: Modeling Simulation and Visualization for Medical Device Design

PI: Daniel Keefe
Grant No.:
1R01EB018205
Project collaborators:
Arthur Erdman

Biomedical Simulations Resource

PI: David D'Argenio
Grant No.:
P41 EB001978
Project collaborators:
PI: Vasilis Marmarelis
Grant No.:
N/A
Project collaborators:
David D'Argenio, Ted Berger, Michael Khoo

Biosimulation of Surgical Vocal Fold Injury

PI: Nicole Yee-Key Li-Jessen
Grant No.:
R03DC012112
Project collaborators:

Bridging multiple scales in modeling targeted drug nanocarrier delivery

PI: Ravi Radhakrishnan
Grant No.:
NIHU01EB016027
Project collaborators:

Bridging Multiple Scales in Modeling Targeted Drug Nanocarrier Delivery

PI: Portonovo Ayyaswamy
Grant No.:
U01 EB016027
Project collaborators:
David M. Eckmann, Ravi Radhakrishnan

Building analysis tools and a theory framework for inferring principles of neural computation from multi-scale organization in brain recordings

PI: Friedrich Sommer
Grant No.:
1R01EB026955
Project collaborators:

BUILDING MULTILEVEL MODELS OF THERAPEUTIC RESPONSE IN THE LUNGS

PI: Tim Corcoran
Grant No.:
1U01HL131046-01
Project collaborators:

Building Multilevel Models of Therapeutic Response in the Lungs

PI: Robert Parker
Grant No.:
1U01HL131046-01
Project collaborators:
Timothy E. Corcoran

Cardiac Energy Grid

PI: James Bassingthwaighte
Grant No.:
R01 HL122199
Project collaborators:
H Sauro, Dan Beard, Andrew McCulloch, Ranjan Dash, Michael Regnier

CAREER: Multiscale Modeling of a Virtual Kidney during the Onset and Progression of Diabetic Kidney Disease

PI: Ashlee Ford Versypt
Grant No.:
NSF 1845117
Project collaborators:

Center for Integrative Biomedical Engineering, Integration of Uncertainty Quantification with the SCIRun Bioelectric Field Simulation Pipeline

PI: Rob MacLeod
Grant No.:
P41GM103545
Project collaborators:
Chris Johnson, Ross Whitaker, and Dana Brooks, Akil Narayan
PI: Rob MacLeod
Grant No.:
U24EB029012
Project collaborators:
Chris Johnson, Ross Whitaker, and Dana Brooks, Akil Narayan
PI: Rob MacLeod
Grant No.:
P41GM103545
Project collaborators:
Chris Johnson, Ross Whitaker, and Dana Brooks, Akil Narayan
PI: Rob MacLeod
Grant No.:
U24EB029012
Project collaborators:
Chris Johnson, Ross Whitaker, and Dana Brooks, Akil Narayan

Central Mechanisms of Airway Protection

PI: Donald Bolser
Grant No.:
HL103415
Project collaborators:
Kendall Morris

Clinical Data Intelligence & Advanced Analytics to Reduce Drug Diversion across the Care Delivery Cycle and Drug Supply Chain in Health Systems

PI: Tom Knight
Grant No.:
1R44DA044083-01
Project collaborators:

Competing Segment: Models to Predict Protein Biomaterials Performance

Key Personnel: Chi-Hua Yu
Grant No.:
HH4977
Project collaborators:

Competitive Renewal of Development, Improvement and Extension of the Tissue Simulation Environment - CompuCell3D

Key Personnel: Andy Somogyi
Grant No.:
R01GM122424
Project collaborators:

Computational and circuit mechanisms underlying motor control

Key Personnel: Rajendra Bose
Grant No.:
NS104649-01
Project collaborators:

Computational and Circuit Mechanisms Underlying Rapid Learning

Key Personnel: Ariel Rokem
Grant No.:
BRAINU19NS107609
Project collaborators:

Constitutive and Agent Based Multiscale Models to Improve Vein Graft Survival

PI: Roger TRAN-SON-TAY
Grant No.:
1U01HL119178-01
Project collaborators:
Scott Berceli, Marc Garbey, and Rongling Wu

Constitutive and Agent-Based Multiscale Models to Improve Vein Graft Survival

PI: Scott Berceli
Grant No.:
1U01HL119178
Project collaborators:
Marc Garbey, Rongling Wu, Roger Tran-Son-Tay

Controlling the Mechanobiology of Cutaneous Wounds to Reduce Hypertrophic Scar

PI: Ed Sander
Grant No.:
AR063867
Project collaborators:

Cracking the Olfactory Code

PI: Rick Gerkin
Grant No.:
U19NS112953
Project collaborators:

CRCNS: Improving Bioelectronic Selectivity with Intrafascicular Stimulation

PI: James Abbas
Grant No.:
NIH R01 EB027584
Project collaborators:
Ranu Jung

Cross-scale interactions between mineral and collagen for tendon-bone attachment

PI: Guy Genin
Grant No.:
U01EB01642201A1
Project collaborators:
Markus Buehler, Ioannis Chasiotis, Pedro Ponte Castañeda, Stavros Thomopoulos
PI: Markus Buehler
Grant No.:
U01EB016422
Project collaborators:
Ioannis Chasiotis, David Kaplan, Guy Genin, Pedro Ponte Casteñada, Stavros Thomopolous, Joyce Wong
PI: Stavros Thomopoulos
Grant No.:
U01EB016422-01A1
Project collaborators:
Markus Buehler, Ioannis Chasiotis, Guy Genin, Pedro Ponte Casteneda
Key Personnel: Ioannis Chasiotis
Grant No.:
U01EB016422-01A1
Project collaborators:
Markus Buehler, Guy Genin, Pedro Ponte Casteñada, Stavros Thomopoulos
Key Personnel: Pedro Ponte Casteneda
Grant No.:
U01EB016422-01A1
Project collaborators:
Markus Buehler, Ioannis Chasiotis, Guy Genin, Stavros Thomopoulos

Data-driven analysis for neuronal dynamic modeling

PI: Gal Mishne
Grant No.:
R01EB026936
Project collaborators:

Developing MSM Methodologies

PI: Terence Sanger
Grant No.:
EB021921
Project collaborators:
Simon Giszter

Development of a Multiscale Mechanistic Simulation of Acetaminophen Induced Liver

Key Personnel: Jim Sluka
Grant No.:
U01-GM111243-01
Project collaborators:
Glazier, James Alexander; Dunn, Kenneth W.; Klaunig, James E

Diagnosis of Alzheimers Disease Using Dynamic High-Order Brain Networks

Key Personnel: Han Zhang
Grant No.:
BRAINR01EB022880
Project collaborators:
Key Personnel: Zhen Zhou
Grant No.:
BRAINR01EB022880
Project collaborators:
PI: Pew-Thian Yap
Grant No.:
EB022880
Project collaborators:

Discovering dynamic computations in large-scale neural activity recordings

PI: Tatiana Engel
Grant No.:
BRAINR01EB026949
Project collaborators:
A. Churchland, K. Shenoy

Dissemination of a tool for data-driven multiscale modeling of brain circuits

PI: Salvador Dura-Bernal
Grant No.:
U24 EB028998-01
Project collaborators:

Don't have one just want to participate and make connections

PI: Tarynn Witten
Grant No.:
my invite email expired before I could respond
Project collaborators:

Efficient resource allocation and information retention in working memory circuits

PI: ShiNung Ching
Grant No.:
EB028154
Project collaborators:
Lawrence Snyder
PI: lawrence snyder
Grant No.:
R01EB028154
Project collaborators:
ShiNung Ching

Embedded Ensemble Encoding

Key Personnel: Sergio Angulo
Grant No.:
EB02290301
Project collaborators:
PI: Srdjan Antic
Grant No.:
EB29633330
Project collaborators:
William Lytton

Extension of NEURON simulator for simulation of reaction-diffusion in neurons, Microconnectomics of neocortex: a multiscale computer model, Embedded Ensemble Encoding, Microconnectomics of neocortex: a multiscale computer model

PI: William Lytton
Grant No.:
R01MH086638
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01MH086638
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal
PI: William Lytton
Grant No.:
R01MH086638
Project collaborators:
Michael Hines, Gordon Shepherd, Robert McDougal, Srdjan Antic, Salvador Dura-Bernal

Emergent dynamics from network connectivity: a minimal model

Key Personnel: Katherine Morrison
Grant No.:
BRAINEB022862
Project collaborators:

Executive committee member

Trainee: Bruno Rego
Grant No.:
NA
Project collaborators:

EXTENSION OF NEURON SIMULATOR FOR SIMULATION OF REACTION-DIFFUSION IN NEURONS

Key Personnel: Adam Newton
Grant No.:
5R01MH086638
Project collaborators:

FEBio: Finite Elements for Biomechanics and Biophysics

PI: Jeff Weiss
Grant No.:
R01GM083925
Project collaborators:

Filtered Point Process Inference Framework for Modeling Neural Data

PI: Emery Brown
Grant No.:
5R01EB022726
Project collaborators:
Mriganka Sur, MIT, Wasim Malik, MGH

Graph theoretical analysis of the effect of brain tumors on functional MRI networks

PI: Hernan Makse
Grant No.:
BRAINR01EB022720
Project collaborators:

Human Neocortical Neurosolver

PI: Stephanie Jones
Grant No.:
EB022889
Project collaborators:

Image Driven Multi-Scale Modeling to Predict Treatment Response in Breast Cancer

Other: Erin Rericha
Grant No.:
1U01 CA174706-01
Project collaborators:
Tom Yankeelov, Vito Quaranta, Mike Miga
Key Personnel: Darren Tyson
Grant No.:
1U01CA174706
Project collaborators:
PI: Thomas Yankeelov
Grant No.:
U01CA174706
Project collaborators:

Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary Hypertension

PI: C. Alberto Figueroa
Grant No.:
U01HL135842
Project collaborators:
PI: Carlos Figueroa
Grant No.:
U01HL135842
Project collaborators:
PI: Seungik Baek
Grant No.:
1U01HL135842
Project collaborators:
Alberto Figueroa

Infarct-related Ventricular Tachycardia Mechanisms: From Micro to Clinical, Simulation guidance of ablation therapy for persistent atrial fibrillation

PI: Natalia Trayanova
Grant No.:
U01HL141074
Project collaborators:
PI: Natalia Trayanova
Grant No.:
U01HL141074
Project collaborators:

Integrating Bioinformatics into Multiscale Models for Hepatocellular Carcinoma

Key Personnel: Lyla Atta
Grant No.:
1U01CA212007-01A1
Project collaborators:
Key Personnel: Emma Bigelow
Grant No.:
n/a
Project collaborators:
Elana Fertig
Key Personnel: Archana Balan
Grant No.:
U01
Project collaborators:

Integrating bioinformatics into multiscale models for hepatocellular carcinoma

Key Personnel: Richard Sové
Grant No.:
U01CA212007
Project collaborators:
Elana Fertig, Aleksander Popel, Phuoc Tran, Andrew Ewald

Integrating bioinformatics into multiscale models for hepatocellular carcinoma

PI: Elana Fertig
Grant No.:
U01CA212007
Project collaborators:
Aleksander Popel, Phuoc Tran, Andrew Ewald
PI: Phuoc Tran
Grant No.:
1U01CA212007
Project collaborators:
Andrew Josef Ewald, PHD; Elana Judith Fertig (contact), PHD; ALEKSANDER S. POPEL, PhD

Integration of Uncertainty Quantification with the SCIRun Bioelectric Field Simulation Pipeline

Other: Dana Brooks
Grant No.:
U24EB029012
Project collaborators:
Akil Narayan, Rob MacLeod
Other: Lindsay Rupp
Grant No.:
U24EB029012
Project collaborators:
Rob MacLeod, Akil Narayan, Chris Johnson, and Dana Brooks, Ross Whitaker
Other: Zexin Liu
Grant No.:
U24EB029012
Project collaborators:
Chris Johnson, Ross Whitaker, Akil Narayan, and Dana Brooks
Key Personnel: Akil Narayan
Grant No.:
U24EB029012
Project collaborators:
and Dana Brooks, Rob MacLeod

Integration of Uncertainty Quantification with the SCIRun Bioelectric Field Simulation Pipeline


Other: Sumientra Rampersad
Grant No.:
U24EB029012
Project collaborators:
Chris Johnson, Ross Whitaker, Akil Narayan, and Dana Brooks, Rob MacLeod

Invasive Approach to Model Human Cortex-Basal Ganglia Action-Regulating Networks

PI: Vasileios Christopoulos
Grant No.:
1U01NS09896101
Project collaborators:

Large-scale Network Modeling for Brain Dynamics: Statistical Learning and Optimization

PI: Xi Luo
Grant No.:
R01EB022911
Project collaborators:

Learning spatio-temporal statistics from the environment in recurrent networks

PI: Nicolas Brunel
Grant No.:
EB022891
Project collaborators:
Harel Shouval

MANIFOLD-VALUED STATISTICAL MODELS FOR LONGITUDINAL MORPHOMETIC ANALYSIS IN PRECLINICAL ALZHEIMER'S DISEASE (AD)

PI: Vikas Singh
Grant No.:
R01EB022883
Project collaborators:

MEASURING, MODELING, AND MODULATING CROSS-FREQUENCY COUPLING

PI: Mark Kramer
Grant No.:
R01EB026938
Project collaborators:
Alik Widge, Uri Eden

Mechanisms of neural circuit dynamics in working memory and decision-making

Key Personnel: Manuel Schottdorf
Grant No.:
5U19NS104648
Project collaborators:

Mental, measurement, and model complexity in neuroscience

PI: Joshua Gold
Grant No.:
EB026945
Project collaborators:
Vijay Balasubramanian

Micro-Temporal Proesses Underlying Health Behavior Adoption and Maintenance (microT Study)

PI: Stephen Intille
Grant No.:
1U01HL146327
Project collaborators:

Microtemporal Processes Underlying Health Behavior Adoption and Maintenance

PI: Genevieve Dunton
Grant No.:
U01HL146327
Project collaborators:

Model for Platelet Adhesion and Thrombus Formation

PI: Michael King
Grant No.:
HL097971
Project collaborators:

Modeling and analysis of material transport in complex geometry of neurons

PI: Jessica Zhang
Grant No.:
NSF-CBET 1804929
Project collaborators:

Modeling bi-directional signaling and cytoskeletal dynamics in 3D cell migrations

PI: Roger Kamm
Grant No.:
1U01CA177799-01
Project collaborators:
Muhammad Zaman, Douglas Lauffenburger, Frank Gertler

MODELING BI-DIRECTIONAL SIGNALING AND CYTOSKELETAL DYNAMICS IN 3D CELL MIGRATIONS

PI: Muhammad Zaman
Grant No.:
5U01CA177799
Project collaborators:

Modeling Brainstem Inflammation's Role in Systemic Dysfunction during Sepsis

PI: Thomas E. Dick
Grant No.:
U01 EB021960-01A1
Project collaborators:
Kenneth A Loparo, Frank J. Jacono, Yoram Vodovotz, Yaroslav Molkov, Yee-Hsee Hsieh

MODELING BRAINSTEM INFLAMMATION'S ROLE IN SYSTEMIC MODELING BRAINSTEM INFLAMMATION'S ROLE IN SYSTEMIC

Key Personnel: William Barnett
Grant No.:
U01 EB 021960
Project collaborators:

Modeling multi-area dynamics during motor control

Key Personnel: Larry Abbott
Grant No.:
1U19NS104649-01
Project collaborators:

Modeling Multiscale Control of Liver Regeneration

PI: Rajanikanth Vadigepalli
Grant No.:
EB023224
Project collaborators:

Modeling the Role of Brainstem Inflammation in Systemic Dysfunction during Sepsis.

Key Personnel: Frank Jacono
Grant No.:
1U01EB021960-01A1
Project collaborators:
Thomas E. Dick, Kenneth A. Loparo, Yoram Vodovotz, Yaroslav Molkov

MODELLING THE GROWTH OF THE MIC NICHE AT THE SYSTEM LEVEL

Key Personnel: Jing Su
Grant No.:
5U01CA166886-03
Project collaborators:

Models and methods for calcium imaging data, with application to the Allen Brain Observatory

PI: Daniela Witten
Grant No.:
5R01EB026908
Project collaborators:
Michael Buice

Models to Predict Protein Biomaterial Performance

Key Personnel: Davoud Ebrahimi
Grant No.:
U01 EB014976
Project collaborators:
PI: David Kaplan
Grant No.:
U01EB014976
Project collaborators:
Markus Buehler (MIT), Joyce Wong (BU)

Models to predict protein biomedical performance

PI: Joyce Wong
Grant No.:
U01 EB014976
Project collaborators:

Modular design of multiscale models, with an application to the innate immune response to fungal respiratory pathogens

PI: Reinhard Laubenbacher
Grant No.:
1U01EB02450101
Project collaborators:
Key Personnel: Joseph Masison
Grant No.:
1U01EB024501
Project collaborators:

MSM proposal currently in review

PI: Silvia Blemker
Grant No.:
NA
Project collaborators:

Multi-region 'Network of Networks' Recurrent Neural Network Models of Adaptive and Maladaptive Learning

PI: Kanaka Rajan
Grant No.:
1R01EB02816601
Project collaborators:
Karl Deisseroth - Stanford University; Kafui Dzirasa - Duke University; Peter Rudebeck - Mount Sinai; Helen Mayberg - Mount Sinai

Multi-Scale Laws of Myocardial Growth and Remodeling

PI: Ellen Kuhl
Grant No.:
U01-HL119578
Project collaborators:
PI: julius guccione
Grant No.:
U01HL119578
Project collaborators:

Multi-scale modeling of gas transport through channels in living cells

Key Personnel: Ahmad Raeisi Najafi
Grant No.:
U01-GM111251
Project collaborators:

Multi-scale modeling of genetic variation in a developmental network

Other: Paul Marjoram
Grant No.:
1U01GM103804
Project collaborators:
Nuzhdin, De Pace, Rohs
PI: Angela DePace
Grant No.:
1 U01 GM103804-01A1
Project collaborators:
Sergey Nuzhdin, Remo Rohs, Paul Marjoram

Multi-scale modeling of influenza vaccination strategies for optimal T cell immunity

PI: Veronika Zarnitsyna
Grant No.:
U01HL139483
Project collaborators:

Multi-Scale Modeling to Predict Long-Term Growth and Remodeling of Skin in Response to Stretch

PI: Adrian Buganza Tepole
Grant No.:
R01AR074525
Project collaborators:

MULTIMODALITY IMAGING-DRIVEN MULTIFIDELITY MODELING OF AORTIC DISSECTION

Key Personnel: Minglang Yin
Grant No.:
U01HL142518
Project collaborators:

Multiscale . Model of the vagal outflow to the heart

PI: james schwaber
Grant No.:
UO1HL133360
Project collaborators:
Rajanikanth Vadigepalli

Multiscale Analysis of Trauma

Key Personnel: Evan Tsiklidis
Grant No.:
U01-HL-131053
Project collaborators:
PI: Scott Diamond
Grant No.:
131053
Project collaborators:
Talid Sinno, Carrie Sims, Lawrence Brass, Yannis Kevrekidis

Multiscale modeling and empirical study of a mechanism limiting blood clot growth

PI: Mark Alber
Grant No.:
1U01HL116330
Project collaborators:
Dr. John Weisel, University of Pennsylvania School of Medicine

Multiscale modeling and empirical study of a mechanism limiting blood clot growth.

Key Personnel: Zhiliang Xu
Grant No.:
NIH: IU01HL116330-01A1
Project collaborators:
Mark Alber, Rustem Litvinov, John Weisel

Multiscale Modeling for Treatment discovery in Duchenne Muscular Dystrophy

PI: Shayn Peirce-Cottler
Grant No.:
U01AR06939301
Project collaborators:
Silvia Blemker

Multiscale Modeling of Blood Flow and Platelet Mediated Thrombosis

PI: Danny Bluestein
Grant No.:
5U01HL131052
Project collaborators:
Yuefan Deng, Marvin J Slepian

Multiscale Modeling of Bone Environment Responses to Metastatic Prostate Cancer

PI: David Basanta
Grant No.:
U01CA202958
Project collaborators:

Multiscale Modeling of Bone Environment Responses to Metastatic Prostate Cancer

PI: Conor Lynch
Grant No.:
U01CA202958
Project collaborators:

Multiscale modeling of cerebral blood flow and oxygen transport

PI: Timothy Secomb
Grant No.:
U01 HL133362
Project collaborators:
Sava Sakadzic, David Boas

Multiscale Modeling of Circadian Rhthyms

PI: William (Bill) Cannon
Grant No.:
1U01EB02254601
Project collaborators:
Jay Dunlap, Dartmouth; Jennifer Hurley, RPI

Multiscale Modeling of Circadian Rhythms

Key Personnel: Samuel Britton
Grant No.:
U01EB022546
Project collaborators:
William Cannon, Jay Dunlap, Jennifer Hurley, Mark Alber

Multiscale Modeling of Clotting Risk in Atrial Fibrillation

PI: Boyce Griffith
Grant No.:
U01HL143336
Project collaborators:

Multiscale Modeling of Gas Transport Through Channels in Living Cells

Key Personnel: Paween Mahinthichaichan
Grant No.:
U01-GM111251
Project collaborators:

MULTISCALE MODELING OF INFLUENZA VACCINATION STRATEGIES FOR OPTIMAL T CELL IMMUNITY

Key Personnel: Zheng-Rong Li
Grant No.:
U01HL139483
Project collaborators:

Multiscale modeling of influenza vaccination strategies for optimal T cell immunity

PI: Jacob Kohlmeier
Grant No.:
HL139483
Project collaborators:
Veronika Zarnitsyna

Multiscale modeling of inherited cardiomyopathies and therapeutic interventions

PI: Jonathan Wenk
Grant No.:
U01HL133359
Project collaborators:
PI: Kenneth Campbell
Grant No.:
HL133359
Project collaborators:

Multiscale Modeling of Lung Disease-Influenced Aerosol Dosimetry

Key Personnel: Andrew Kuprat
Grant No.:
1U01ES028669-01A1
Project collaborators:
Chantal Darquenne, Richard Corley, Bahman Asgharian
PI: Chantal Darquenne
Grant No.:
1 U01 ES028669-01A1
Project collaborators:

Multiscale modeling of metabolic and regulatory networks

Key Personnel: Neeraj Kumar
Grant No.:
N/A
Project collaborators:
William Cannon

Multiscale Modeling of Sickle Cell Anemia: Methods and Validation

PI: George Karniadakis
Grant No.:
U01HL11447601
Project collaborators:
MIT (Ming Dao), MGH (John Higgins), U Houston (Peter Vekilov)

Multiscale Modeling of Sickle Cell Anemia: Methods and Validation

PI: Ming Dao
Grant No.:
U01HL114476
Project collaborators:
George Karniadakis
Key Personnel: Xuejin Li
Grant No.:
U01HL114476
Project collaborators:

Multiscale modeling of the cocktail party problem

PI: Mounya Elhilali
Grant No.:
U01AG058532
Project collaborators:

Multiscale modeling of the failing heart for cardiac resynchronization therapy

PI: Andrew McCulloch
Grant No.:
1R01HL096544
Project collaborators:
David Krummen, Jeffrey Omens

Multiscale Modeling of the Mammalian Circadian Clock: The Role of GABA Signaling

PI: Michael Henson
Grant No.:
U01 EB021956-01
Project collaborators:

Multiscale modeling of the mammalian circadian clock: The Role of GABA Signaling

PI: Erik Herzog
Grant No.:
U01EB021956
Project collaborators:
Michael Henson and Yannis Kevrekidis

Multiscale Modeling of Wound Healing

PI: Jason Haugh
Grant No.:
U01EB018816
Project collaborators:
James Bear (UNC-Chapel Hill), Timothy Elston (UNC-Chapel Hill)

Multiscale modeling to map cardiac electrophysiology between species

PI: Eric Sobie
Grant No.:
U01 HL 136297
Project collaborators:
David Christini
PI: David Christini
Grant No.:
U01HL136297
Project collaborators:
Eric Sobie

Multiscale Models of Cardiac Growth, Remodeling, and Myocardial Infarction

PI: Jeff Holmes
Grant No.:
U01 HL-120862
Project collaborators:

MULTISCALE MODELS OF NEURAL POPULATION CONTROL IN SPINAL CORD

PI: Simon Giszter
Grant No.:
U01 EB021921
Project collaborators:
Terence Sanger
Key Personnel: Simon Giszter
Grant No.:
U01 EB021921
Project collaborators:
Terence D Sanger

Multiscale Models of Wound Cell Plasticity for Regeneration

PI: Qing Nie
Grant No.:
U01AR073159
Project collaborators:

Multiscale Molecular Systems Biology- Reconstruction and Model Optimization

PI: Ronan Fleming
Grant No.:
SC0010429
Project collaborators:
Michael Saunders (Stanford University), Bernhard Palsson (UCSD)

Multiscale Molecular Systems Biology: Reconstruction and Model Optimization

PI: Michael Saunders
Grant No.:
U01GM102098
Project collaborators:
Bernhard Palsson, Ronan Fleming, Ines Thiele

Multiscale Multiphysics Model of Thrombus Biomechanics in Aortic Dissection

PI: Jay Humphrey
Grant No.:
U01HL116323
Project collaborators:
George Karniadakis
PI: Jay Humphrey
Grant No.:
U01 HL116323
Project collaborators:
George Karniadakis

Multiscale spatiotemporal modeling of cardiac mitochondria

PI: Mohsin Jafri
Grant No.:
1U01HL116321-01A1
Project collaborators:
PHD William Jonathan Lederer (contact), MD CARMEN A. MANNELLA
PI: W. Jonathan Lederer
Grant No.:
1U01HL116321
Project collaborators:
MOHSIN Saleet JAFRI, PHD William Jonathan Lederer (contact), MD CARMEN A. MANNELLA, PhD

Multiscale, Transport-Dependent NO Signaling: Cells to Vascular Networks

Key Personnel: Kenneth Barbee
Grant No.:
1U01HL116256-01A1
Project collaborators:
Dov Jaron, Donald Buerk

Multiscale, Transport-Dependent NO Signalling: Cells to Vascular Networks

Key Personnel: Donald Buerk
Grant No.:
U01 HL116256
Project collaborators:
Dov Jaron, Ken Barbee

N/A (from NCI CSBC program)

PI: Aaron Meyer
Grant No.:
N/A
Project collaborators:

N/A (Working with OpenSim in BioMch working group)

Key Personnel: Jacqueline Tran
Grant No.:
N/A (Working with OpenSim in BioMch working group)
Project collaborators:

National Resource for Cell Analysis and Modeling

PI: Leslie Loew
Grant No.:
P41GM103313
Project collaborators:

Neuronal population dynamics within and across cortical areas

PI: Matthew Smith
Grant No.:
EB026953
Project collaborators:
PI: Byron Yu
Grant No.:
BRAINR01EB026953
Project collaborators:
Doiron, Brent, Smith, Matthew

New methods and theories to interrogate organizational principles from single cell to neuronal networks

PI: Mara Dierssen
Grant No.:
TMMEB28159
Project collaborators:
Key Personnel: Linus Manubens-Gil
Grant No.:
BRAINR01EB028159
Project collaborators:
PI: Bing Ye
Grant No.:
1R01EB028159
Project collaborators:
Mara Dierssen

NIAMS: CORT Innovations to Assess and Forestall Post-Traumatic Osteoarthritis

Key Personnel: Bruce Ayati
Grant No.:
1 p50 AR055533
Project collaborators:
James Martin, Joseph Buckwalter

NIH - Age Dependent Mecahnical Ventilator induced Inflammation: Modeling and Experiments

PI: Ramana Pidaparti
Grant No.:
NIH (R01AG041823)
Project collaborators:
Angela Reynolds and Rebecca Heise

NIH MIDAS and DTRA CNIMS

PI: Madhav Marathe
Grant No.:
Dont remember
Project collaborators:

No project title

Key Personnel: Blanca Pineda
Grant No.:
No grant number
Project collaborators:

None

PI: Anahita Akbari
Grant No.:
None
Project collaborators:

NOVEL BAYESIAN LINEAR DYNAMICAL SYSTEMS-BASED METHODS FOR DISCOVERING HUMAN BRAIN CIRCUIT DYNAMICS IN HEALTH AND DISEASE

PI: Vinod Menon
Grant No.:
R01EB022907
Project collaborators:

Operationalizing Behavioral Theory for mHealth: Dynamics, Context, and Personalization

PI: Donna Spruijt-Metz
Grant No.:
U01CA229445
Project collaborators:
Benjamin Marlin, Pedja Klasnja, Misha Pavel, Eric Hekler, Daniel Rivera

OPERATIONALIZING BEHAVIORAL THEORY FOR MHEALTH: DYNAMICS, CONTEXT, AND PERSONALIZATION

PI: Benjamin Marlin
Grant No.:
1 U01 CA229445 01
Project collaborators:
Donna Spruijt-Metz, Predrag Klasnja, Eric Hekler, Daniel Rivera, Misha Pavel

Oxytocin modulation of neural circuit function and behavior

Key Personnel: Alisa Surkis
Grant No.:
U19 NS107616
Project collaborators:

Oxytocin Modulation of Neural Circuit Function and Behavior

PI: Robert Froemke
Grant No.:
NS107616
Project collaborators:
Key Personnel: Luisa Schuster
Grant No.:
1U19NS107616-01
Project collaborators:
Key Personnel: Peter Petersen
Grant No.:
BRAINU19NS107616
Project collaborators:

Peri-procedural transmural electrophysiological imaging of scar-related ventricular tachycardia

PI: Linwei Wang
Grant No.:
R01HL145590-01
Project collaborators:

Predicting Cell Deformation from Body Level Mechanical Loads

PI: Ahmet Erdemir
Grant No.:
R01EB009643
Project collaborators:

Predictive modeling of bioelectric activity on mammalian multilayered neuronal stimulation

PI: Gianluca Lazzi
Grant No.:
U01EB025830
Project collaborators:
Ted Berger
PI: Theodore Berger
Grant No.:
U01GM104604
Project collaborators:
Gianluca Lazzi

Predictive Modeling of Bioelectric Activity on Mammalian Multilayered Neuronal Structures in the Presence of Supraphysiological Electric Fields

Key Personnel: Jean-Marie Bouteiller
Grant No.:
GM104604
Project collaborators:
Gianluca Lazzi, Ted Berger
Key Personnel: Gene Yu
Grant No.:
5U01EB025830
Project collaborators:
PI: Dong Song
Grant No.:
9U01EB025830
Project collaborators:

PREDICTIVE MULTISCALE IN SILICO CARDIO-PHARMACOLOGY

Key Personnel: Igor Vorobyov
Grant No.:
5U01HL126273-03
Project collaborators:
PI: Colleen Clancy
Grant No.:
1U01HL126273-01A1
Project collaborators:
Vladimir Yarov-Yarovoy, Robert D. Harvey

Predictive multiscale in silico cardio-pharmacology

Key Personnel: Parya Aghasafari
Grant No.:
U01HL126273
Project collaborators:

Predictive Multiscale in Silico Cardio-Pharmacology

Key Personnel: Pei-Chi Yang
Grant No.:
5U01HL126273-04
Project collaborators:

Predictive Multiscale Modeling of Microbial Consortia Biofilms

PI: Ross Carlson
Grant No.:
U01EB019416
Project collaborators:

Quantifying Causality for Neuroscience

PI: Konrad Kording
Grant No.:
EB028162
Project collaborators:

Readout and control of spatiotemporal neuronal codes

PI: Wolfgang Losert
Grant No.:
1U19NS107464
Project collaborators:

Real-time Statistical Algorithms for Controlling Neural Dynamics and Behavior

PI: Il Memming Park
Grant No.:
EB026946
Project collaborators:
jonathan pillow, alfredo fontanini, carlos brody

Real-time statistical algorithms for controlling neural dynamics and behavior

PI: Jonathan Pillow
Grant No.:
1R01EB026946
Project collaborators:
Il Memming Park

Recruitment of Dr. Benjamin Fregly, Established Investigator

Key Personnel: Andrew Baines
Grant No.:
RR170026
Project collaborators:

Reproducible Modeling Center

PI: Herbert Sauro
Grant No.:
NA
Project collaborators:
Jonathan Karr, Ion Moraru, David Nickerson, John Gennari

Robust Predictors of Mania and Psychosis

PI: Justin Baker
Grant No.:
U01MH116925
Project collaborators:

Sequence Learning in Recurrent Neural Networks

PI: Harel Shouval
Grant No.:
R01EB022891
Project collaborators:
Nicolas Brunel

Simulation guidance of ablation therapy for persistent atrial fibrillation

Key Personnel: Patrick Boyle
Grant No.:
U01-HL-141074
Project collaborators:
Natalia Trayanova, Hugh Calkins, Adityo Prakosa

Software for Practical Annotation and Exchange of Virtual Anatomy

PI: Andinet Enquobahrie
Grant No.:
R01EB025212
Project collaborators:

Spinal Circuits for the Control of Dexterous Movement

Trainee: Graziana Gatto
Grant No.:
1U19NS11295901
Project collaborators:

Stochastic Simulation Service: A Cloud Computing Framework for Modeling and Simulation of Stochastic Biochemical Systems

Key Personnel: Brian Drawert
Grant No.:
R01EB014877
Project collaborators:
Linda Petzold

StochSS: A Next-Generation Toolkit for Simulation-Driven Biological Discovery

PI: Linda Petzold
Grant No.:
2R01EB01487704A1
Project collaborators:
Andreas Hellander; Uppsala University, Brian Drawert; UNC Asheville

Systems Biology of Hypertrophic Heart Disease from Molecular Pathways to Organ System

Key Personnel: Ali Khalilimeybodi
Grant No.:
R01HL137100
Project collaborators:

Systems Modeling Guided Bone Regeneration

PI: Xiaobo Zhou
Grant No.:
1U01AR06939501A1
Project collaborators:
YANG, YUNZHI

Systems Modeling Guided Bone regeneration

PI: Yunzhi Yang
Grant No.:
1U01AR069395
Project collaborators:
Xiaobo Zhou

SYSTEMS PHARMACOLOGY MODEL FOR SPATIAL CONTROL OF CARDIAC FIBROSIS

PI: Jeffrey Saucerman
Grant No.:
5R01HL137755
Project collaborators:
Jeffrey Holmes, Shayn Peirce-Cottler

The Center for Innovation in Intensive Longitudinal Studies (CIILS)

PI: Sy-Miin Chow
Grant No.:
U24 EB026436-01
Project collaborators:
NA

Tools for modeling state-dependent sensory encoding by neural populations across spatial and temporal scales

PI: Stephen David
Grant No.:
BRAINR01EB028155
Project collaborators:

Toward a Theory for Macroscopic Neural Computation Based on Laplace Transform

PI: Marc Howard
Grant No.:
EB022864
Project collaborators:
Michael Hasselmo

Towards a Complete Description of the Circuitry Underlying Sharp Wave-Mediated Memory Replay

Key Personnel: Aaron Milstein
Grant No.:
U19NS104590
Project collaborators:

TOWARDS A COMPLETE DESCRIPTION OF THE CIRCUITRY UNDERLYING SHARP WAVE-MEDIATED MEMORY REPLAY

Other: Ben Dichter
Grant No.:
NS104590
Project collaborators:

Transport Phenomena in the Lymphatic System

PI: James Moore
Grant No.:
U01HL123420
Project collaborators:
David Zawieja
Key Personnel: Michael Moreno
Grant No.:
HL123420
Project collaborators:

U01HL114476

Key Personnel: He Li
Grant No.:
N/A
Project collaborators:

Uncovering Population-Level Cellular Relationships to Behavior via Mesoscale Networks

PI: David Carlson
Grant No.:
BRAINEB026937
Project collaborators:
Guillermo Saprio, Kafui Dzirasa

USC Physical Sciences-Oncology Center

Government Program Official: Sean Hanlon
Grant No.:
U54CA143907
Project collaborators:

VPOP (Virtual Populations for Obesity Prevention)

PI: Bruce Lee
Grant No.:
U01HD086861
Project collaborators:
Other: Sarah Rebbert
Grant No.:
U01HD086861
Project collaborators:

 Operationalizing Behavioral Theory for mHealth: Dynamics, Context, and Personalization

Key Personnel: Misha Pavel
Grant No.:
1U01CA229445-01
Project collaborators:

“Integrating Bioinformatics into Multiscale Models for Hepatocellular Carcinoma”

Key Personnel: Gaurav Sharma
Grant No.:
U01CA212007
Project collaborators: