The project is to develop a full-scale model of rat hippocampus using compartmental models of individual neurons. The code available can be used to construct the connectivity for an entorhinal-dentate network with lateral and medial entorhinal cortical cells as spike generators and compartmental models of dentate granule cells and basket cells. The code can then be used to run simulations using the network.
- Yu, G.J., Bouteiller, J.-M.C., Song, D., and Berger, T.W. Axonal anatomy optimizes spatial encoding in the rat entorhinal-dentate system: A computational study. IEEE Transactions on Biomedical Engineering, 2019, 1-1, DOI: 10.1109/TBME.2019.2894410.
- Bingham, C.S., Loizos, K., Yu, G.J., Gilbert, A., Bouteiller, J.-M.C., Song, D., Lazzi, G., and Berger, T.W. Model-based analysis of electrode placement and pulse amplitude for hippocampal stimulation. IEEE Transactions on Biomedical Engineering, 2018, 99, 1-1, DOI: 10.1109/TBME.2018.2791860.
- Hendrickson, P.J., Yu, G.J., Song, D., and Berger, T. W. A millionplus neuron model of the hippocampal dentate gyrus: Critical role for topography in determining spatiotemporal network dynamics. IEEE Transactions on Biomedical Engineering, 2015, 63(1), DOI: 10.1109/TBME.2015.2445771.