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Open Knee(s): virtual biomechanical representations of the knee joint

What is being modeled?
Human knee joint (tibifemoral and patellofemoral) and its soft tissue structures (cartilage, menisci, ligaments)
Description & purpose of resource

This resource is a project website to provide free access to three-dimensional finite element representations of the knee joint and open development of knee models for collaborative testing and use.

Open knee(s) is a growing database of specimen specific finite element models of the human knee joint. Open Knee(s) - Generation 1 was disseminated in 2010. For open Knee(s) - Generation 2, There are currently eight models being developed for the database representing a wide range of the adult population based on donor age and joint health. The goal of the project is to utilize specimen specific geometry, joint and tissue level mechanical response to develop the models. All the specifications, raw and derivative data including models are routinely publicly disseminated.

This project was funded by the National Institute of General Medical Sciences, National Institutes of Health (1R01GM104139). Early activities were partially funded by the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health (1R01EB009643).

Spatial scales
tissue
organ
Temporal scales
10-3 - 1 s
1 - 103 s
This resource is currently
under early-stage development
mature and useful in ongoing research
a demonstration or a framework to be built upon (perhaps with a sample implementation)
likely to require significant study prior to effective reuse
likely to be usable without detailed knowledge of its internals
Key publications (e.g. describing or using resource)

Erdemir, A. (2016) Open Knee: open source modeling and simulation in knee biomechanics, Journal of Knee Surgery, 29, 107-116. DOI: https://dx.doi.org/10.1055%2Fs-0035-1564600. PubMed Central: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876308/.

Collaborators
Ahmet Erdemir
PI contact information
erdemira@ccf.org
Keywords
knee
finite element
cartilage
meniscus
ligament
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