Active learning of cortical connectivity from two-photon imaging data

Spatial scales
cellular
Temporal scales
10-3 - 1 s
1 - 103 s
This resource is currently
a demonstration or a framework to be built upon (perhaps with a sample implementation)
Collaborators
Dario Ringach, Guillermo Sapiro, David Dunson
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Models of Protein Biomaterials

What is being modeled?
Silk and Silk-elastin-like proteins (SELPs)
Description & purpose of resource

Silk project;
-Replica exchange molecular dynamics is used to develop a structure for the silk chimeras.
-MD is also used to explain the change in integrin folding associated with its activation due to interactions with inorganic surfaces


Silk elastin project:
- Replica exchange molecular dynamics to guide design of elastin domains in SELPs (silk elastin like proteins)

Spatial scales
molecular
Temporal scales
<10-6 s (chemical reactions)
This resource is currently
under early-stage development
mature and useful in ongoing research
Collaborators
Markus Buehler, David Kaplan
PI contact information
mbuehler@mit.edu, david.kaplan@tufts.edu
Keywords
MSM U01
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