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3D GranSim

What is being modeled?
Tuberculosis (TB) granuloma formation and function in the lung
Description & purpose of resource

GranSim is a hybrid agent-based computational model (ABM) that describes the formation and function of a granuloma during Mycobacterium tuberculosis infection in the lung. Although granulomas are 3D entities, due to the high computational costs associated to simulate a 3D version, GranSim has been developed and curated since 2004 only in 2D. [2-4, 6-10] This website and the recent manuscript [hyperlink here] illustrate our first attempt to simulate a 3D TB granuloma in the lung.

Denise Kirschner
PI contact information
Lung model
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