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The MIcro Simulation Tool (MIST)

What is being modeled?
Population / Disease Progression
Description & purpose of resource

The MIcro Simulation Tool is free software to support disease modeling. It is a Monte-Carlo micro-simulation compiler that employs High Performance Computing.

MIST has unique population generation capabilities.

MIST runs over the cloud!

The Reference Model for Disease Progression uses MIST as its engine

Spatial scales
whole organism
Temporal scales
<10-6 s (chemical reactions)
10-6 - 10-3 s
10-3 - 1 s
1 - 103 s
weeks to months
human lifetime
multiple generations
This resource is currently
mature and useful in ongoing research
a demonstration or a framework to be built upon (perhaps with a sample implementation)
likely to be usable without detailed knowledge of its internals
Has this resource been validated?
How has the resource been validated?

MIST distribution includes tests that are made public that test its integrity and validity. This includes critical tests, statistical tests, and reproducibility tests.

The test examples are documented and documentation is released with the software. 

The Reference Model uses MIST for 7 years as its engine and MIST was used to model mental health model and Sepsis.

Can this resource be associated with other resources? (e.g.: modular models, linked tools and platforms)
Which resources?

MIST uses the Inspyred library to perform Evolutionary Computation.

The Reference Model for Disease Progression uses MIST as the simulation engine


Key publications (e.g. describing or using resource)

The Reference Model provides additional publications describing uses of MIST:


Jacob Barhak
PI contact information
population generation
Evolutionary Computation
high performance computing
Disease Modeling
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