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scRCMF: Identification of Cell Subpopulations and Transition States From Single-Cell Transcriptomes

What is being modeled?
Transition states in single-cell transcriptomes
Description & purpose of resource

scRCMF is an unsupervised method that identifies stable cell states and transition cells by adopting a nonlinear optimization model that infers the latent
substructures from a gene-cell matrix.

Spatial scales
cellular
tissue
Temporal scales
1 - 103 s
hours
days
weeks to months
This resource is currently
mature and useful in ongoing research
Has this resource been validated?
Yes
Can this resource be associated with other resources? (e.g.: modular models, linked tools and platforms)
Yes
Key publications (e.g. describing or using resource)

Zheng, Xiaoying, et al. "scRCMF: Identification of Cell Subpopulations and Transition States From Single-Cell Transcriptomes." IEEE Transactions on Biomedical Engineering 67.5 (2019): 1418-1428.

Collaborators
Qing Nie
PI contact information
qnie@uci.edu
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