Integrated multiscale biomaterials experiment and modeling group (ImuBEAM) - 2014 MSM


Working Group Co-Leads:

  • Markus Buehler (MIT)
  • Guy Genin (WUSTL)

Goals and Objectives:

This WG aims to provide an active forum to foster, report and assess interactions between experimental and computational groups engaged in the design, synthesis and testing of hierarchical biomaterials. Key issues to be explored are to identify common approaches, tested methods and validation steps, and to develop ways to make maximum impact in the medical community. We also anticipate sharing activities such as the organization of conferences and workshops, and tutorials. Our vision is that the discussions lead to a set of tools, data, software, training and related products for the broader community. The membership of this WG is diverse and brings together a group of people who do not regularly interact.

We plan to work on joint workshops, symposia, organize webinars, and promote the close integration of biomaterials experiment and modeling in diverse scientific communities.

Group Members:

  • Mark Bathe (MIT)
  • David Breslauer (Refractored Materials)
  • Markus Buehler (MIT)
  • Ioannis Chasiotis (UIUC)
  • Changqing Chen (Tsinghua)
  • Horacio Espinosa (Northwestern)
  • Guy Genin (WUSTL)
  • Jeff Holmes (Virginia)
  • Songbai Ji (Dartmouth)
  • David Kaplan (Tufts)
  • Roland Kaunas (Texas A&M)
  • Spencer Lake (WUSTL)
  • Pedro Ponte Casteñada (UPenn)
  • Paolo Provenzano (Minnesota)
  • Stavros Thomopoulos (WUSTL)
  • Mark Van Dyke (Wake Forest)
  • Jeff Weiss (Utah)
  • Tony Weiss (U. Sydney)
  • Joyce Wong (BU)
  • Feng Xu (Xi'an Jiaotong)
  • Michael Yu (Johns Hopkins)
  • Sulin Zhang (Penn State)

Retreats and Workshops

  • SITEP Workshop, held on June 10, 2014 at Tufts University (download agenda here). Participants: All team members of the U01 grant, and several visitors, including Professor Carole Perry (University of Nottingham, UK). Download images: Audience Presenters. The purpose of the retreat was to have in-depth discussions of all project parts, challenge students and postdocs from all three research groups to jointly prepare and present materials, and to collectively discuss next steps and plans for the next year. Collection of slides from the retreat can be downloaded here.

Events Sponsored

  • NEMB 2013: This conference was a great success. Held in February 2013 in Boston, it featured top plenary lectures by acclaimed scientists such as Robert Langer, Rakesh Jain, David Mooney, Sam Gambhir and Don Ingber ( The conference included many stimulating discussions on multiscale experiment and modeling. The Conference Chair, Markus Buehler, and the Program Chair, Guy Genin now co-lead the IμBEAM Working Group. Other outcomes of the conference included scientific discussions, several tutorials for young scientists. The conference was an excellent forum overall for the integration of medical and engineering sciences. The NEMB conference was incredibly successful and a follow-up conference was held in 2014.
  • NEMB 2014: The ASME 2014 3rd Global Congress on NanoEngineering for Medicine and Biology (NEMB2014) was held Feb. 2-5, 2014 in San Francisco, CA ( The 2014 Congress focused on the integration of engineering, materials science, and nanotechnology in addressing fundamental problems in biology and medicine, and had a strong focus on integration of experiment and modeling for biomaterials. Plenary and keynote speakers relevant to our working group included Paul Alivisatos, Mina Bissell, Tejal Desai, Albert Folch, Dorit Hanein, Kam Leong, Luke Lee, CT Lim, Arun Majumdar, Kit Parker, Stephen Quake, G. Ravichandran, John Rogers, Molly Stevens, Sam Stupp, Mehmet Toner, and Jennifer West. IμBEAM members played central roles on the organizing committee: Markus Buehler was honorary chair of the conference, Guy Genin served on the steering committee, and Roland Kaunas, Paolo Provenzano, and Feng Xu served as track chairs.
  • 2014 WCB: The World Congress on Biomechanics ( included three symposia and one workshop on integrated multiscale experiment and modeling, organized by our working group. The first was a series of sessions co-organized by Stavros Thomopoulos on the multiscale mechanics of hierarchical tissues. Markus Buehler co-organized a session on design, fabrication, and analysis of hierarchical tissues. Guy Genin and Roland Kaunas organized a series of sessions on integration of theory and experiment in multi-scale modeling of living cells; Viola Vogel presented a keynote talk in this symposium. Guy Genin also co-organized an NSF-sponsored workshop on the role of multiscale modeling in the BRAIN initiative. Jeff Weiss presented a multiple-session symposium on multiscale modeling using the FEBio platform.

Presentations and Materials

  • Webinar on Feb. 10, 2014 Part delivered by Markus Buehler (more coming soon!)
  • Webinar on May 21, 2014 Webinar entitled "Multi-Scale Modeling of Scar Formation: Towards In Situ Design of Better Scar," delivered by Jeff Holmes
  • [1] Commentary: The Materials Project: A materials genome approach to accelerating materials innovation (Jain et al., APL Materials, 2004): This is an interesting read and also relevant for some of the work going on in the biomaterials area

MSM Meetings

2013 Meeting:

  • Poster download (PDF) "Integrated Computational Modeling and Experimental Design of Functional Protein Biomaterials" by Shangchao Lin, Olena Tokareva, Anna Tarakanova, Matthew Jacobsen, Wenwen Huang, Qin Wang, David Li, Joyce Y. Wong, David L. Kaplan, and Markus J. Buehler (NIH U01 EB014976)

2014 Meeting:

  • David Kaplan, Joyce Wong, Markus Buehler are scheduled to give a special presentation at the 2014 MSM Meeting.
  • The ImuBEAM will have a breakout session at the IMAG 2014 meeting (September 3, 2014; 12:45 – 2:15pm; Bldg. 45 Balcony B).
  • Agenda: WG participants and interested attendees will discuss activities, challenges and new opportunities. The WG leadership will report back to the IMAG community in a plenary presentation at 5:10-5:20 pm.
Table sorting checkbox