Microconnectomics of the Primary Motor Cortex: A Multiscale Computer Model

Abstract:

IMAG/MSM Cell-to-Macroscale WG Webinar

Melissa Knothe Tate

Thursday, September 8, 2016 POSTPONED

3:30 pm  |  Eastern Daylight Time (New York, GMT-04:00)  |  1 hr

Meeting number (access code): 625 902 234, password: kiwi

1-877-668-4493 Call-in toll-free number (US/Canada)

1-650-479-3208 Call-in toll number (US/Canada)

Please note that Webex is not fully compatible with Windows 10.

High resolution images of cells demonstrate the highly heterogeneous nature of both the nuclear and cytosolic spaces. We are interested in understanding how this complex environment might influence the dynamics of cellular processes. To investigate this question we have worked to develop particle-based stochastic reaction-diffusion methods that can track the spatial transport and reaction of individual molecules within domains derived from imaging data.

Challenges in integrating experiment and models across scales at the attachment of tendon to bone

This talk will explore the complex interdisciplinary software systems developed to support the 32-site international PREDICTHD project that aims to better characterize disease progression in Huntington’s disease.  Key aspects of how software engineering best practices are applied by an interdisciplinary team of computer scientists, software engineers, biostatisticians, and clinical investigators to accelerate the analysis and understanding of distributed and heterogeneous data sources will be presented.    This presentation will describe the infrastructure and environmen

In the last few years there have been dramatic increases in the range and quality of information available from non-invasive medical imaging methods, so that several potentially valuable imaging measurements are now available to quantitatively measure tumor growth, assess tumor status as well as anatomical or functional details. Using different methods such as the CT scan, magnetic resonance imaging (MRI), or positron emission tomography (PET), it is now possible to evaluate and define tumor status at different levels: physiological, molecular and cellular.

MDIC presents an informative series of online teleconference workshops featuring emerging trends in medical technology regulatory science, MDIC projects and subject matter experts sharing perspectives, progress and opportunities.

Initial Telecon Hosted by:

MDIC Computational Modeling & Simulation (CM&S) Project

Thursday, December 4th, 2014, 3:00pm – 4:00pm EST

Agenda

5 minutes | Overview

By engineering the length scales, morphology, crystallography and chemistry of interfaces, nanocomposites can deliver mechanical properties that exceed what could be achieved from a single-phase material alone.