JSim Consolidated Model Database
Showing 51 - 100 of 432 models found. [New Search]
NSR0055 (in NSR archive): NaCaX
An ion channel, a sodium calcium exchanger in the surface membrane (sarcolemma) of mammalian pacemaker cells. A mathematical model for the electrophysiological responses.
An ion channel, a sodium calcium exchanger in the surface membrane (sarcolemma) of mammalian pacemaker cells. A mathematical model for the electrophysiological responses.
- Key terms: Sodium calcium exchanger, ion channel, sarcolemma, sarcoplasmic reticulum, cardiac cell, sinoatrial, electrochemical gradient
- NaCaX
NSR0056 (in NSR archive): poisson
This function generates a Poisson-like PDF using a scaled Poisson equation in which lambda is allowed to vary continuously and n is fixed. This curve represents the transport of a tracer through n identical well mixed compartments.
This function generates a Poisson-like PDF using a scaled Poisson equation in which lambda is allowed to vary continuously and n is fixed. This curve represents the transport of a tracer through n identical well mixed compartments.
- Key terms: poisson distribution, probability density function, pdf
- poisson
NSR0058 (in NSR archive): BTEX40_MID_heart
Blood tissue exchange model for heart capillaries uses literature values for constants to fit multiple indicator dilution data from tracer data through perfused dog hearts. Estimates for permeability surface areas for each solute are made.
Blood tissue exchange model for heart capillaries uses literature values for constants to fit multiple indicator dilution data from tracer data through perfused dog hearts. Estimates for permeability surface areas for each solute are made.
- Key terms: Multiple indicator dilution, permeability-surface area, albumin, sucrose, glucose, potassium, sodium, radiotracer, outflow, extraction, data
- BTEX40_MID_heart
NSR0060 (in NSR archive): Myogenic_Compliant_Vessel
This model simulates the flow through a passive and actively responding vessel driven by a sinusoidal pressure input.
This model simulates the flow through a passive and actively responding vessel driven by a sinusoidal pressure input.
- Key terms: Resistance, Compliance, Myogenic response, Regulation, Vessel, Pressure, Flow, Law of Laplace, Ohm's Law, Cardiovascular system, Hemodynamics
- Myogenic_Compliant_Vessel
NSR0066 (in NSR archive): Thin_Wall_Compliant_Vessel
This model uses simulates the flow through a single vessel with resistance to flow R and compliance of the vessel, C, derived from a thin walled formulation of vessel wall mechanics.
This model uses simulates the flow through a single vessel with resistance to flow R and compliance of the vessel, C, derived from a thin walled formulation of vessel wall mechanics.
- Key terms: thin, wall, compliant, vessel, compliant, resistance, flow, Cardiovascular System, Hemodynamics
- Thin_Wall_Compliant_Vessel
NSR0068 (in NSR archive): Pressure_Driven_Single_Vessel
This model simulates the single_vessel model with the addition of a pressure-driven flow input. This is analogous to a compliant, resistive vessel with an inflow on one end and an aperture for outflow on the other end.
This model simulates the single_vessel model with the addition of a pressure-driven flow input. This is analogous to a compliant, resistive vessel with an inflow on one end and an aperture for outflow on the other end.
- Key terms: pressure, driven, single, vessel, flow, compliance, output, flow, input, RC circuit
- Pressure_Driven_Single_Vessel
NSR0070 (in NSR archive): 4-State_Sarcomere_Energetics
The 4-State model of sarcomeric contraction created by Landesberg and Sideman is investigated in terms of the energy liberated by the system as a function of the rate of shortening.
The 4-State model of sarcomeric contraction created by Landesberg and Sideman is investigated in terms of the energy liberated by the system as a function of the rate of shortening.
- Key terms: Sarcomere, Toponin, Energy liberation, Crossbridge model, Actin, Myosin, Cardiovascular System, Cardiac contraction, Crossbridge, 4-State Model Energetics
- 4-State_Sarcomere_Energetics
NSR0072 (in NSR archive): Airway_bronchiole_alveolus
This model represents an inertial flow in a rigid airway, compliant bronchiole, compliant bronchiolus and a compliant alveolus.
This model represents an inertial flow in a rigid airway, compliant bronchiole, compliant bronchiolus and a compliant alveolus.
- Key terms: Airway, Bronchiole, Bronchiolus, Alveolus, Compliant alveolus, Compliant airway, Compliant bronchiole, Compliant bronchiolus, Respiratory system, respiratory mechanics
- Airway_bronchiole_alveolus
NSR0074 (in NSR archive): Arterial_flow_with_O2_CO2_HCO3_H_exch
Distributed model for the O2-CO2 transport and exchange in the arterial portion of the vasculature.
Distributed model for the O2-CO2 transport and exchange in the arterial portion of the vasculature.
- Key terms: Oxyhemoglobin dissociation curves, Bohr effect, Haldane effect, Axially distributed model, Hematocrit and RBC/plasma relative velocity, Artery, arterial flow, Transport Physiology, Combined convection diffusion permeation reaction, HCO3, CO2, oxygen, carbon dioxide, hydrogen ion
- Arterial_flow_with_O2_CO2_HCO3_H_exch
NSR0075 (in NSR archive): Baroreceptor_Lu_et_al_2001
The model simulates baroreceptor function by changing heart rate, ventricular contractility, and arterial resistance in response to an input aortic pressure signal.
The model simulates baroreceptor function by changing heart rate, ventricular contractility, and arterial resistance in response to an input aortic pressure signal.
- Key terms: baroreceptor, heart rate control, cardiovascular system, sympathetic control, parasympathetic control, arterial resistance, contractility, Lu, afferent pathway, efferent pathway, Publication, data, Nervous system, autonomic system
- Baroreceptor_Lu_et_al_2001
NSR0077 (in NSR archive): Beard2005_Mito_OxidatPhosphor
A model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
A model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
- Key terms: oxidative phosphorylation, mitochondria, energy metabolism, Cellular and Molecular Physiology, Cell metabolism models, cell respiration, Publication, biochemical systems, PMID16163394
- Beard2005_Mito_OxidatPhosphor
NSR0078 (in NSR archive): BeelerReuter77
Cardiac Action Potential with Ca, K, and Na currents. Beeler-Reuter 1977 paper.
Cardiac Action Potential with Ca, K, and Na currents. Beeler-Reuter 1977 paper.
- Key terms: Cardiac electrophysiology, ionic currents, voltage clamp, dog canine heart, ventricular fibre, fiber action potential, cardiomyocyte, Nernst potential, time and voltage-dependent time constants, cell physiology
- BeelerReuter77
NSR0082 (in NSR archive): BTEX40
Models a tissue cylinder consisting of four regions: interstitial fluid, endothelial cells, and parenchymal cells.
Models a tissue cylinder consisting of four regions: interstitial fluid, endothelial cells, and parenchymal cells.
- Key terms: BTEX40, PDE, convection, diffusion, permeation, reaction, distributed, capillary, plasma, isf, interstitial fluid, endothelial, parenchymal, cell
- BTEX40
NSR0083 (in NSR archive): BTEX50
Models a tissue cylinder consisting of five regions: plasma, interstitial fluid,endothelial cells, parenchymal cells, and mitochondria.
Models a tissue cylinder consisting of five regions: plasma, interstitial fluid,endothelial cells, parenchymal cells, and mitochondria.
- Key terms: BTEX50, PDE, convection, diffusion, permeation, reaction, distributed, capillary, plasma, isf, interstitial fluid, endothelial, parenchymal, cell, mitochondria
- BTEX50
NSR0084 (in NSR archive): gentex
GENTEX is a whole organ model of the vascular network providing intraorgan flow heterogeneity and accounts for substrate transmembrane transport, binding, and metabolism in erythrocytes, plasma, endothelial cells, interstitial space, and cardiomyocytes.
GENTEX is a whole organ model of the vascular network providing intraorgan flow heterogeneity and accounts for substrate transmembrane transport, binding, and metabolism in erythrocytes, plasma, endothelial cells, interstitial space, and cardiomyocytes.
- Key terms: purine nucleoside metabolism, convection-diffusion-reaction model, GENTEX, transporter, red blood cell, axially distributed blood-tissue exchange processes, constrained parameter estimation, simultaneous optimization, BTEX, blood tissue exchange
- gentex
NSR0085 (in NSR archive): Vessel_Resistance_Only
Model rigid vessel flow with vessels of varying diameter and length in series and in parallel. Model 'Two_Resistors' uses two vessels in series and model 'Four_resistors' has two vessels in parallel and two more in series.
Model rigid vessel flow with vessels of varying diameter and length in series and in parallel. Model 'Two_Resistors' uses two vessels in series and model 'Four_resistors' has two vessels in parallel and two more in series.
- Key terms: blood flow, series, parallel resistors, circulatory system, rigid vessel, vessel network, two resistors, four resistors, tutorial, tube impedence
- Vessel_Resistance_Only
NSR0086 (in NSR archive): Goldman
Model of transmembrane resting potential due to concentration differences in K, Na, and Ca across a membrane with constant conductance for each ion.
Model of transmembrane resting potential due to concentration differences in K, Na, and Ca across a membrane with constant conductance for each ion.
- Key terms: Channel Nernst potential, ionic current, gating current, conformational state, Tutorial, Electrophysiology, membrane potential
- Goldman
NSR0089 (in NSR archive): Myo_Dyn_Resp_wFit
This model describes the dynamic response of a vessel after a step increase in intraluminal pressure.
This model describes the dynamic response of a vessel after a step increase in intraluminal pressure.
- Key terms: vascular smooth muscle, Data, intraluminal pressure, circulatory vessel, myogenic response, Cardiovascular system, Blood flow, Autoregulation, arteriole, Acive contraction, pressure
- Myo_Dyn_Resp_wFit
NSR0090 (in NSR archive): CardiacOutput_refHuman
Cardiac output estimation in reference human. An open-loop cardiovascular model composed of a four-chamber varying-elastance heart, a systemic circulation, a pulmonary circulation, a coronary circulation, and baroreceptors.
Cardiac output estimation in reference human. An open-loop cardiovascular model composed of a four-chamber varying-elastance heart, a systemic circulation, a pulmonary circulation, a coronary circulation, and baroreceptors.
- Key terms: cardiac output estimation, cardiovascular system, baroreceptor, systemic circulation, pulmonary circulation, coronary circulation, clinical application, automated parameterization, Publication, Data, PMID17846886, Integrative Physiology
- CardiacOutput_refHuman
NSR0091 (in NSR archive): CardiopulmonaryMechanics
A closed loop cardiopulmonary model composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a pulmonary circulation, a coronary circulation, airways mechanics, and baroreceptors.
A closed loop cardiopulmonary model composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a pulmonary circulation, a coronary circulation, airways mechanics, and baroreceptors.
- Key terms: cardiovascular, cardiopulmonary, pericardium, heart, systemic circulation, pulmonary circulation, coronary circulation, lumped parameter, baroreceptor, airway mechanics, integrated physiology, integrative
- CardiopulmonaryMechanics
NSR0092 (in NSR archive): CardiopulmonMechGasExch
A closed loop cardiopulmonary model composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a pulmonary circulation, a coronary circulation, airways mechanics, baroreceptors, and gas exchange.
A closed loop cardiopulmonary model composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a pulmonary circulation, a coronary circulation, airways mechanics, baroreceptors, and gas exchange.
- Key terms: cardiovascular, pulmonary, gas exchange, cardiopulmonary mechanics, pericardium, heart, systemic circulation, pulmonary circulation, coronary circulation, lumped parameter, baroreceptor, oxygen, carbon dioxide, nitrogen, airway mechanics, integrated physiology, integrative, gas exchange
- CardiopulmonMechGasExch
NSR0093 (in NSR archive): CardiopulmonMechGasBloodExch
A closed loop cardiopulmonary model composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a pulmonary circulation, a coronary circulation, airways mechanics, baroreceptors, gas exchange, and blood gas handling.
A closed loop cardiopulmonary model composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a pulmonary circulation, a coronary circulation, airways mechanics, baroreceptors, gas exchange, and blood gas handling.
- Key terms: cardiovascular, pulmonary, gas exchange, blood gas handling, pericardium, heart, systemic circulation, pulmonary circulation, coronary circulation, lumped parameter, baroreceptor, oxygen, carbon dioxide, bicarbonate, carboxyhemoglobin, pH, nitrogen, airway mechanics, integrated physiology, cardiopulmonary mechanics, Integrative
- CardiopulmonMechGasBloodExch
NSR0094 (in NSR archive): Adenosine_mid4
Four region blood-tissue exchange (BTEX) model used to fit data from Schwartz 1999 MID experiments involving cardiac endothelial transport and metabolism of adenosine and inosine.
Four region blood-tissue exchange (BTEX) model used to fit data from Schwartz 1999 MID experiments involving cardiac endothelial transport and metabolism of adenosine and inosine.
- Key terms: Adenosine, inosine, multiple indicator dilution, four region, PMID10484446, Data, transport, metabolism, cardiac endothelium, inosine, hypoxanthine, xanthine, uric acid, BTEX
- Adenosine_mid4
NSR0095 (in NSR archive): Circ_with_Baroreceptors
A closed loop cardiopulmonary model composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a pulmonary circulation, a coronary circulation, and baroreceptors.
A closed loop cardiopulmonary model composed of a four-chamber varying-elastance heart, a pericardium, a systemic circulation, a pulmonary circulation, a coronary circulation, and baroreceptors.
- Key terms: cardiovascular, pericardium, heart, systemic circulation, pulmonary circulation, coronary circulation, lumped parameter, baroreceptor, integrated physiology, integrative
- Circ_with_Baroreceptors
NSR0096 (in NSR archive): One_Enz_Reverse.MM
First-order reversible enzymatic reaction with binding of either substrate or product to enzyme and allows thermodynamic equilibrium. Uses two methods, the enzyme binding and
First-order reversible enzymatic reaction with binding of either substrate or product to enzyme and allows thermodynamic equilibrium. Uses two methods, the enzyme binding and
- Key terms: Transport Physiology, Chemical Reaction Enzymes, Enzymatic Reaction, Single Enzyme, Reversible, Michaelis-Menten Kinetics, Briggs-Haldane Kinetics
- One_Enz_Reverse.MM
NSR0097 (in NSR archive): Waniewski2009
(Matlab) Distributed modeling of osmotically driven fluid transport in peritoneal dialysis: theoretical and computational investigations
(Matlab) Distributed modeling of osmotically driven fluid transport in peritoneal dialysis: theoretical and computational investigations
- Key terms: osmosis, interstitial hydraulic conductivity, capillary hydraulic permeability, reflection coefficient, mathematical modeling, Publication
- Waniewski2009
NSR0099 (in NSR archive): EC_SMC_Kapela_Microcirc2009
A mathematical model of vasoreactivity in rat mesenteric arterioles: I. Myoendothelial communication
A mathematical model of vasoreactivity in rat mesenteric arterioles: I. Myoendothelial communication
- Key terms: calcium dynamics, gap junctions, nitric oxide, EDHF, computer simulations, endothelium, arteriol smooth muscle, norepinephrine, vasoreactivity, electrophysiology, NIHMS205708
- EC_SMC_Kapela_Microcirc2009
NSR0100 (in NSR archive): SMC_Kapela_JTB2008_NitricOxideStimulation
A mathematical model of Ca2+ dynamics in rat mesenteric smooth muscle cell: agonist and NO stimulation.
A mathematical model of Ca2+ dynamics in rat mesenteric smooth muscle cell: agonist and NO stimulation.
- Key terms: calcium dynamics, gap junctions, ion channels, nitric oxide, microcirculation, arteriol smooth muscle, norepinephrine, vascular tone, electrophysiology, membrane potential, publication
- SMC_Kapela_JTB2008_NitricOxideStimulation