Combined Mechanistic and Input-Output Modeling of the Hippocampus During Spatial Navigation

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PI: SONG, DONG

Email: dsong@usc.edu

Institution: University of Southern California

Title: Combined Mechanistic and Input-Output Modeling of the Hippocampus During Spatial Navigation

Grant #: DA055665

Status: Active

Deliverables: A modeling framework inspired by the generative adversarial network (GAN)

  • Full-scale mechanistic model as the generative model (Aim 1)
  • Large-scale input-output model-based discriminative model  (Aim 2 & 3)
  • A GAN-like procedure that (1) identifies discrepancies between the mechanistic model and the real hippocampus, (2) hierarchically optimizes the mechanistic model, and (3) suggests new experimental validations (Aim 3 & 4)

GAN-like Paradigm

TMM Project Slide (One-Page):

TMM Project - Dong Song_0.pptx1.37 MB

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