BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)

Funding Opportunity Purpose

This FOA solicits new theories, computational models, and statistical tools to derive understanding of brain function from complex neuroscience data.  Proposed tools could include the creation of new theories, ideas, and conceptual frameworks to organize/unify data and infer general principles of brain function; new computational models to develop testable hypotheses and design/drive experiments; and new mathematical and statistical methods to support or refute a stated hypothesis about brain function, and/or assist in detecting dynamical features and patterns in complex brain data.  It is expected that the tools developed under this FOA will be made widely available to the neuroscience research community for their use and modification.  Investigative studies should be limited to validity testing of the tools being developed.

Posted Date

October 12, 2017

Open Date (Earliest Submission Date)

November 15, 2017

Letter of Intent Due Date(s)

November 15, 2017; August 4, 2018; August 3, 2019

Application Due Date(s)

New Dates December 15, 2017; September 4, 2018; September 3, 2019  by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates.  No late applications will be accepted for this Funding Opportunity Announcement.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

AIDS Application Due Date(s)

Not Applicable

Scientific Merit Review

New Dates May 2018, February 2019, February 2020

Advisory Council Review

New Dates August 2018, May 2019, May 2020

Earliest Start Date

September 2018, September 2019, September 2020,

Expiration Date

New Date September 4, 2019 per issuance of NOT-EB-18-012. (Original Expiration Date: October 18, 2019)

Due Dates for E.O. 12372

Not Applicable


Activity Code (e.g., RO1, U01)
Funding Announcement Number
Posted Date
Expiration Date
Letter of Intent Due Date
Application Due Date
Participating Organizations
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