2024 Agenda

Setting up TEAMS for Biomedical Digital Twins

(Teaming4BDT)

Interactive AGENDA

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Moderators, Speakers, and Scribes, please open each agenda item below to find specific instructions for your session.

 

Agenda Color Code Key


Day 1: Defining Biomedical Digital Twins (BDT)

Click here for: Day 1 Zoom Participation Link

September 30, 2024

Click Here to view speaker information

Time & Location Activity Organizers

 

8:00-8:30am

Lobby, Poster Room


Check-in at Registration

Set up posters

Registration Desk

 

8:30-8:45am

Main Meeting Room


 

Welcome

Meeting Vision and Goals

IMAG: Grace Peng

Team Science: Michelle Bennett

MSM: Gary An

 

8:45-9:15am

Main Meeting Room

NASEM Digital Twin Definition and Application to Biomedical
Research

 

Speaker: Caroline Chung

Moderator: Gary An

 

 

9:15-10:15am

Main Meeting Room

Panel Discussion: Unique Features of Biomedical Digital Twins:
Examples of Pre-Meeting Exercise #1

Moderator: Caroline Chung

Speakers: William Lytton, Carlos Lopez, Gary An, Peter Hunter

 

10:15-10:45am

Cafeteria, Poster Rooms

AM Refreshments

View Posters

Refreshments Courtesy of the
Society for Mathematical Biology

 

10:45-11:45am

Main Meeting Room

Breakout Discussion: Apply the NASEM Definition to Your
Biomedical Digital Twin Idea - Addressing Fit for Purpose

Lead Moderator: Michelle Bennett

Room Moderators: Caroline Chung, William Lytton, Carlos Lopez, Gary An, Peter Hunter

11:45-1:00pm

Poster Room

Main Room

Lunch and Networking

View Posters

Post BDT Ideas

Walk to Pike & Rose

 

Part 1: 1:00-1:30pm

Part 2: 1:30-2:00pm

Main Meeting Room

Addressing Gaps and Challenges for Successful BDT Implementation - Part 1

NASEM DT Components Beyond Fit-for-Purpose

Part 1: Technical Components

Part 2: Social Components

Moderator: Gary An

Speakers: Reinhard Laubenbacher, Julian Goldman, Michelle Bennett, Barbara Evans

2:00-4:00pm

Introductions: 2:00-2:30pm

Round 1: 2:30-3:15pm

Round 2: 3:15-4:00pm

Breakout Rooms A, B, and C

Breakout Session #1: Generating Requirements for BDT

Breakout Room A: Verification, Validation, and Uncertainty Quantification (VVUQ); Mathematical and Statistical Foundations for BDT

Breakout Room A Zoom Participation Link

Breakout Room B: Physical Assets/Data Collection/Sensors; Virtual to Physical Control Algorithms/Expert in the Loop

Breakout Room B Zoom Participation Link

Breakout Room C: Ethical, Security Issues; Team Science, Governance

Breakout Room C Zoom Participation Link

Introduction: Michelle Bennett

Breakout Room A: Reinhard Laubenbacher, Anirban Chaudhuri

Scribes: Fariba Fahroo, Yuliya Gorb

Breakout Room B: Julian Goldman, Sandy Weininger

Scribes: Julia Berzhanskaya, Yulia Gel

Breakout Room C: Barbara Evans, Michelle Bennett

Scribes: Hannah Dueck, Elena Sizikova

 4:00-4:30pm

Cafeteria

Poster Rooms

Main Room

PM Refreshments

View Posters

Post BDT Ideas

Refreshments Courtesy of the
Society for Mathematical Biology

4:30-5:00pm

Main Meeting Room

Preparing for Teaming Day 2: Create Initiative BDT Teams Around BDT Ideas

Moderator: Michelle Bennett

4:55-5:00pm Conclude Day 1 Speakers: Grace Peng, Gary An, Michelle Bennett
5:00pm

Adjourn Day 1

Dinner & Bocce at Pinstripes

 

 

 

 

 

 

 

 

 

 

 

 

 

 


 

Day 2: Approaches to address BDT challenges

Click here for: Day 2 Zoom Participation Link

October 1, 2024

Click Here to view speaker information

Time & Location Activity Organizers

8:00-8:30am

Lobby, Poster Room

Check-In

View poster comments

Registration Desk


8:30-8:45am

Main Meeting Room

Welcome Back

Recap from Day 1

Speakers: Grace Peng, Julia Berzhanskaya, Eric Stahlberg, Michelle Bennett

8:45-9:15am

Main Meeting Room

Report Back on Requirements Template for BDT

Speakers: Reinhard Laubenbacher, Anirban Chaudhuri, Sandy Weininger, Julian Goldman, Michelle Bennett, Barbara Evans

 

9:15-10:15am

Main Meeting Room

First BDT Ideas Teaming Session Breakout Discussion

Round #1: "Getting Started: Using the Definition"

Moderator: Michelle Bennett

10:15-10:45am

Poster Room

AM Refreshments

View Posters

Refreshments Courtesy of the
Society for Mathematical Biology

10:45-11:45am

Main Meeting Room

Addressing Gaps and Challenges for Successful BDT Implementation - Part 2

Deeper Dive into BDT Components

Moderator: Julia Berzhanskaya

Speakers: Natalia Trayanova, Ralph Smith, Maria Eduarda Montezzo Coelho, Barbara Evans

11:45-12:00pm

Main Meeting Room

Introduction to Breakout Group Session #2: Generating Assessment Criteria for BDT Speaker: Michelle Bennett

12:00-1:15pm

Poster Room

Main Room

Lunch and Networking

View Posters

Post & Respond to BDT Ideas

Pike & Rose

1:15 - 2:45pm

 

Round 1: 1:15-2:00pm

Round 2: 2:00-2:45pm

Breakout Rooms A, B, and C

Breakout Session #2: Generating Assessment Criteria for BDT

Breakout Room A: Modularity/Interoperability/Systems of Systems Mindset

Breakout Room A Zoom Participation Link

Breakout Room B: Sustainability, Regulatory Issues

Breakout Room B Zoom Participation Link

Breakout Room C: Data/Knowledge Systems

Breakout Room C Zoom Participation Link

Breakout Room A: Natalia Trayanova, Peter Hunter

Scribes: Zhilan Feng, Hannah Dueck

Breakout Room B: Maria Eduarda Montezzo Coelho, Dan Isaacs

Scribes: Yulia Gel, Sandy Weininger

Breakout Room C: Ralph Smith, Eric Stahlberg

Scribes: Yuliya Gorb, Julia Berzhanskaya

2:45-3:15pm

Poster Room

PM Refreshments

View Posters

Post & Respond to BDT Ideas

Refreshments Courtesy of the
Society for Mathematical Biology

3:15-3:45pm

Main Meeting Room

Report Out on Assessment Criteria Templates for BDT

Speakers: Natalia Trayanova, Peter Hunter, Dan Isaacs, Maria Eduarda Montezzo Coelho, Ralph Smith, Eric Stahlberg 

3:45-4:30pm

Main Meeting Room

Second BDT Ideas Teaming Session

Round #2: "Thinking About the Requirements and Assessment Criteria Templates"

Moderator: Michelle Bennett

4:30-5:00pm

BDT Teams Report on Progress

Feedback, Comments, and Suggestions Exercise

Moderator: Michelle Bennett
5:00-5:10pm

Conclude Day 2

Day 2 Accomplishments and Plans for Day 3

Speakers: Grace Peng, Julia Berzhanskaya, Eric Stahlberg, Michelle Bennett

 

 

 

 


 

 

Day 3: Operationalizing Team Science for BDT

Click here for: Day 3 Zoom Participation Link

October 2, 2024

Click Here to view speaker information

Time & Location Activity Organizers


8:00-8:30am

Lobby, Poster Room

Check-In

Review posters

Registration Desk

8:30-8:45am

Main Meeting Room

Welcome Back

Speakers: Grace Peng, Hannah Dueck, Michelle Bennett

8:45-9:00am Recap: Requirements Template and Assessment Criteria/Questions Moderator: Hannah Dueck

 9:00-10:00am

Main Meeting Room

Third BDT Ideas Teaming Session

Round #3: "Creating a Pitch: Putting it All Together"

Moderator: Michelle Bennett

10:00-10:30am

Poster Room

AM Refreshments Refreshments Courtesy of the
Society for Mathematical Biology

10:30-12:30pm

Breakout Rooms A, B, and C

Pitches and Testing Assessment Criteria

Pitches by BDT Idea Teams

Main Room Zoom: Peter Hunter

Breakout Room A Zoom: Eric Stahlberg

Breakout Room C Zoom: Feilim Mac Gabhann and Grace Peng

12:30-1:45pm

Lunch & Networking

Pike & Rose

1:45-2:15pm

Main Meeting Room

Full Group Debrief on Pitch/Assessment Sessions

Presenter: Michelle Bennett

2:15-2:45pm

Main Meeting Room

Next Steps for Biomedical Digital Twins Moderators: Gary An, Hannah Dueck

2:45-3:30pm

Conclude Conference

Moderator: Grace Peng

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Comment

Comment

Interesting that there is no discussion of the cost of developing DT's. A typical modern drug costs in the vicinity of $1B to develop. Given the breadth and complexity of DT's, compared to developing a single drug intended for a single application, the costs of developing DTs will be significantly higher. Where will the (minimally) tens of billions of dollars come from?

Submitted by Jim Sluka on Fri, 08/09/2024 - 12:59

Comment

It would be interesting to include a panels on the economics as well. I could see making a digital twin as being less or more expensive than developing a new drug, depending on the complexity of the DT, what data is already available and how its used.

Comment

Hopefully there will be session on how to actually implement a small-scale BDT as a use case with code and data. One of the main reasons I am attending is to get information on implementation and learning about the software/code needed.

Submitted by pankaj.agarwal… on Thu, 09/26/2024 - 16:18

Comment

Could be interested in working on white paper--James Glazier, jaglazier@gmail.com, might be interested in helping organize next meeting next time depending topic

Submitted by Anonymous (not verified) on Wed, 10/02/2024 - 15:20

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