Setting up TEAMS for Biomedical Digital Twins
(Teaming4BDT)
DRAFT Interactive AGENDA
(Post your comments in the agenda links below -- use Slack for informal chatter)
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Click here for: Day 1 Webcast (TBA) September 30, 2024 |
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| Time & Location | Activity | Organizers |
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8:00-8:30am Atrium, Poster Room |
Set up posters |
Registration Desk |
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8:30-8:45am Main Meeting Room
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Grace Peng, Reed Shabman, Liz Ginexi - IMAG Co-Chairs MSM: Gary An, Peter Hunter IMAG: Hannah Dueck, Yulia Gel, Yuliya Gorb, Orlando Lopez
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8:45-9:15am Main Meeting Room |
NASEM Digital Twin Definition and Application to Biomedical |
Speaker: Caroline Chung Moderator: Gary An
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9:15-10:15am Main Meeting Room |
Panel Discussion: Unique Features of Biomedical Digital Twins: |
Moderator: Caroline Chung Speakers: William Lytton, Carlos Lopez, Gary An, Peter Hunter |
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10:15-10:45am Cafeteria, Poster Rooms |
AM Refreshments |
Refreshments Courtesy of the Society for Mathematical Biology |
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10:45-11:45am Main Meeting Room |
Lead Moderator: Caroline Chung Room Moderators: William Lytton, Carlos Lopez, Gary An, Peter Hunter |
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11:45-1:00pm Pike & Rose |
Lunch and Networking Post BDT Ideas |
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Part 1: 1:00-1:30pm Part 2: 1:30-2:00pm Main Meeting Room |
BDT Pitfalls - Why BDTs Fail - Part 1 What is missing from proposals that lead to their failure in review? Introduction: Describe Necessary Components Beyond Fit-for-Purpose Part 1: Presentation of Technical Pitfalls Part 2: Presentation of Social Pitfalls |
Moderator: Gary An Speakers: Reinhard Laubenbacher, Julian Goldman, Michelle Bennett, Barbara Evans |
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2:00-4:00pm Introductions: 2:00-2:30pm Round 1: 2:30-3:15pm Round 2: 3:15-4:00pm Breakout Rooms A, B, and C |
Breakout Session #1: Generating Requirements for BDT Breakout Room A: Verification, Validation, and Uncertainty Quantification (VVUQ); Mathematical and Statistical Foundations for BDT Breakout Room B: Physical Assets/Data Collection/Sensors; Virtual to Physical Control Algorithms/Expert in the Loop Breakout Room C: Ethical, Security Issues; Team Science, Governance |
Introduction: Michelle Bennett Breakout Room A: Reinhard Laubenbacher Breakout Room B: Julian Goldman Breakout Room C: Barbara Evans and Michelle Bennett |
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4:00-4:30pm Cafeteria, Poster Rooms |
PM Refreshments Post BDT Ideas |
Refreshments Courtesy of the |
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4:30-5:00pm Main Meeting Room |
Preparing for Teaming Day 2: Create Initiative BDT Teams Around BDT Ideas |
Moderator: Michelle Bennett |
| 4:55-5:00pm | Conclude Day 1 | Speakers: Grace Peng, Gary An, Michelle Bennett |
| 5:00pm |
Adjourn Day 1 |
Dinner & Bocce at Pinstripes |
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Day 2: Approaches to address BDT challenges Click here for: Day 2 Webcast (TBA) October 1, 2024 |
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| Time & Location | Activity | Organizers |
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8:00-8:30am Atrium, Poster Room |
Check-In View poster comments |
Registration Desk |
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Main Meeting Room |
Recap from Day 1 |
Speakers: Grace Peng, Julia Berzhanskaya, Eric Stahlberg, Michelle Bennett |
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8:45-9:15am Main Meeting Room |
Speakers: Gary An, Reinhard Laubenbacher, Julian Goldman, Barbara Evans, Michelle Bennett |
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9:15-10:15am Main Meeting Room |
First BDT Ideas Teaming Session Breakout Discussion Round #1: "Getting Started: Using the Definition" |
Moderator: Michelle Bennett |
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10:15-10:45am Poster Room |
AM Refreshments |
Refreshments Courtesy of the Society for Mathematical Biology |
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10:45-11:45am Main Meeting Room |
BDT Pitfalls: Why BDTs Fail - Part 2 Deeper Dive into BDT Pitfalls |
Moderator: Julia Berzhanskaya Speakers: Natalia Trayanova, Ralph Smith, Chris Ritter/Maria Eduarda Montezzo Coelho, James Evans |
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11:45-12:00pm Main Meeting Room |
Introduction to Breakout Group Session #2: Generating Review Criteria for BDT | Speaker: Michelle Bennett |
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12:00-1:15pm Pike & Rose |
Lunch and Networking Post & Respond to BDT Ideas |
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1:15 - 2:45pm Breakout Rooms A, B, and C |
Breakout Session #2: Generating Review Criteria for BDT Breakout Room A: Modularity/Interoperability/Systems of Systems Mindset Breakout Room B: Sustainability, Regulatory Issues Breakout Room C: Data/Knowledge Systems |
Breakout Room A: Natalia Trayanova, Peter Hunter Breakout Room B: Chris Ritter, Maria Eduarda Montezzo Coelho Breakout Room C: Ralph Smith, Eric Stahlberg |
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2:45-3:15pm Poster Room |
PM Refreshments Post & Respond to BDT Ideas |
Refreshments Courtesy of the |
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3:15-3:45pm Main Meeting Room |
Speakers: Julia Berzhanskaya, Natalia Trayanova, Maria Eduarda Montezzo Coelho, Ralph Smith |
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3:45-4:30pm Main Meeting Room |
Second BDT Ideas Teaming Session Round #2: "Thinking About the Requirements and Review Criteria Templates" |
Moderator: Michelle Bennett |
| 4:30-5:00pm |
Feedback and Feedforward Exercise |
Moderator: Michelle Bennett |
| 5:00-5:10pm |
Conclude Day 2 Day 2 Accomplishments and Plans for Day 3 |
Speakers: Grace Peng, Julia Berzhankskaya, Eric Stahlberg, Michelle Bennett |
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Day 3: Operationalizing Team Science for BDT Click here for: Day 3 Webcast (TBA) October 2, 2024 |
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| Time & Location | Activity | Organizers |
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Atrium, Poster Room |
Check-In Review posters |
Registration Desk |
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8:30-8:45am Main Meeting Room |
Recap from Day 1 & Day 2 |
Speakers: Grace Peng, Hannah Dueck, Michelle Bennett |
| 8:45-9:00am | Recap: Requirements Template and Review Criteria/Questions | Moderator: Hannah Dueck |
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9:00-10:00am Main Meeting Room |
Third BDT Ideas Teaming Session Round #3: "Creating a Pitch: Putting it All Together" |
Moderator: Michelle Bennett |
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10:00-10:30am Poster Room |
AM Refreshments | Refreshments Courtesy of the Society for Mathematical Biology |
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10:30-12:30pm Breakout Rooms A, B, and C |
Pitches and Testing Review Criteria Pitches by BDT Idea Teams |
Breakout Room A: Feilim Mac Gabhann Breakout Room B: Bruce Lee Breakout Room C: Carlos Lopez |
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12:30-1:45pm Pike & Rose |
Lunch & Networking |
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1:45-2:15pm Main Meeting Room |
Presenter: Michelle Bennett |
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2:15-2:45pm Main Meeting Room |
Next Steps for: BDT Idea Teams and IMAG/MSM and BDTs | Moderators: Gary An, Hannah Dueck |
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2:45-3:30pm Poster Room |
Conclude Conference |
Moderator: Grace Peng |
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Interesting that there is no discussion of the cost of developing DT's. A typical modern drug costs in the vicinity of $1B to develop. Given the breadth and complexity of DT's, compared to developing a single drug intended for a single application, the costs of developing DTs will be significantly higher. Where will the (minimally) tens of billions of dollars come from?