Modeling of transport and metabolism in whole organs according to Goresky

Introduction

In spite of the spectacular progress in molecular biology in recent years, the main challenge in biological and health sciences lies in the proper quantitative interpretation of carefully designed experiments. This asks for engineering strategies in the design of experiments and a rigorous theoretical basis of their interpretation. Endeavors of this kind are necessary to quantitatively describe and predict metabolic processes, hormonal activities and the pharmacological and toxic properties of drugs.

linear_flow

Linear Flow Coupling. Model I. Const Capillary Transit Time (TT) and Varying Large Vessel TT. Model II. Constant Large Vessel TT and Varying Capillary TT. Model III: Linear relation between capillary and large-vessel TT.

Model number: 0159

Linear Flow Coupling

To model the movement of substances through an organ, the movement along a single path of blood flow through the microcirculation is considered first.

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