MLRd.mod

JSim v1.1

// This is a JSIM.mod adaptation of the C-code detailed below.

// It has been substantially modified, converting many of

// the expressions into ordinary differential equations.

// Rapid equilibria have been transformed into "fast" ODE's

// in order to avoid iterative procedures, complex polynomial

// solutions, etc.

Model: Model study of ATP and ADP buffering, transport of Ca(2+) and Mg(2+), and regulation of ion pumps in ventricular myocytes.

This model is based on the work of A. Michailova and A.D. McCulloch. It has been published in Biophys J. 2001 Aug; 81(2):614-29. It represents an extension of the model by Winslow, et al., Circ. Res. 1999 March 19; 84(5):571-586, found elsewhere at this website under NSR-software-Cellular Models-wrj3. The interface is essentially identical with the exception of an additional button in the lower left hand corner which gives the parameters and fluxes for Michailova and McCulloch's added equations.