Sequence of two catalyzed 1st order Michaelis Menten-type irreversible reactions.
Two irreversible reactions are governed by Michaelis-Menten kinetics. Consider the following two cases for the first reaction, dA/dt = -VmaxA*A/(KmA+A) : Case 1: A<<KmA, The reaction rate is ~VmaxA/Kma and the flux is VmaxA*(A/KmA)<<VmaxA. Case 2: A>>KmA. The reaction rate is ~VmaxA/A and the flux is VmaxA. The reaction rate is slowest when A<<KmA. The flux is greatest when A>>KmA.
Figure plots concentration (mM) as a function of time of substrate A and its reaction products B and C.
Where Concentrations and Km are in mM, and Vmax has units of mM/sec.
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