Multiscale Modeling (MSM) PI Consortium Meeting

Visitor's Information

Hotel Information

Hotel accomodations have been blocked for conference attendees at the Clarion Hotel in downtown Bethesda To make a reservation call (301)654-1000

The Clarion is located within a half a mile of the NIH, however, they also provide hourly shuttles to the NIH Visitor's Center.

The First shuttle leaves the Clarion at 7:30 am, arriving at the NIH visitor's center entrace within 10 minutes.

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Meeting Agenda

Wednesday, April 11 2007

Breakfast on your own

7:30 Shuttle leave Clarion Hotel for NIH Campus

7:30 - 8:00 Set up Posters and Demos

8:00 – 8:30 Welcome

Ron White (NASA)

Tom Russell(NSF)

Marvin Stodolsky (DOE)

Milton Corn (NIH)

Goals for Today (Grace Peng)

8:30-9:30 Summary of April 10, 2007 Workshop on Model Sharing – Maciej Swat and James Glazier

9:30 – 10:30 Project Presentations

Time PI Name Working Group Poster Abstract(s) Poster(s) PI Questionnaire Presentation
9:30 - 9:45 Roger Kamm WG1, WG4 Cytoskeletal Dynamics of Human Erythrocyte Media:2007 MSM Poster_Kamm1.ppt Media:2007MSM PIQ Kamm.doc Media:2007MSM PI Kamm.ppt
Cytoskeletal Modeling and Rheology Not Available
9:45 - 10:00 Peter Ortoleva WG1 From Transcriptional Regulatory Network (TRN) Discovery to Prediction of Cell Behavior Media:2007 MSM Poster_Ortoleva.ppt Media:2007 PIQ Ortoleva.pdf Media:2007MSM PI Ortoleva.ppt
10:00 - 10:15 Jay Schieber WG1 Probing the Multiscale Dynamics of Linear and Branched Polypeptides: Computational and Experimental Approaches Not Available Media:2007MSM PIQ Schieber.doc Media:Schieber_IMAG_PIs_2007_abbreviated.pdf
10:15 - 10:30 Victor Barocas WG1 Multiscale Mechanics of Bioengineered Tissue Media:2007 MSM Poster_Barocas.ppt Not Available Media:2007MSM PI Barocas.ppt

10:30 – 11:00 Break

11:00 – 12:00 Project Presentations

Time PI Name Working Group Poster Abstract(s) Poster (s) PI Questionnaire Presentation
11:00 - 11:15 Anthony Ladd (presented by Jason Butler) WG1 Simulations of polymer solutions in periodic and confined geometries: A lattice-Boltzmann approach Not Available Media:2007MSM PIQ Ladd.doc Media: 2007MSM PP Butler.ppt
11:15 - 11:30 Teresa Head-Gordon (presented by Adam Arkin) WG1 Not Applicable Not Available Not Available Media: 2007MSM PP HeadGordon.ppt
11:30 - 11:45 Yoonsuck Choe WG7 Multiscale Modeling and Analysis of Mouse Brain Microstructure Media:2007 MSM Poster_Choe2.ppt Stanford Response Media:2007MSM PP Choe.pdf
Multiscale Imaging of Mouse Brain Microstructure Media:2007 MSM Poster_Choe1.ppt Texas A&M Response
11:45 - 12:00 James Brasseur WG1, WG5, WG7 Multiscale Modeling of Nutrient Transport and Macro-to-Micro Mixing in the Jejunum Media:2007 MSM Poster_Brasseur2.ppt Media:2007 PIQ Brasseurnew.doc Media:2007MSM PI Brasseur.ppt
Dynamic MRI with 3-D Segmentation and Active Shape Models of the Contractile Behavior of the Rat Small Intestine Media:2007 MSM Poster_Brasseur1.ppt

12:00 – 1:00 Project Presentations

Time PI Name Working Group Poster Abstract(s) Poster (s) PI Questionnaire Presentation
12:00 - 12: 15 Robert Kunz WG3 Progress Towards a Medical Image through CFD Analysis Toolkit for Respiratory Function Assessment on a Clinical Time Scale - PARTS 1 and 2 Part 1

Part 2

Media:2007MSM PI Kunz.doc Media:2007MSM PI Kunz.ppt
Patient Individual Multiscale Geometric Modeling of the Trachea-bronchial Tree Media:2007 MSM Poster_Kunz.ppt
12:15 - 12:30 George Karniadakis WG1, WG3, WG5 A Stochastic Molecular Dynamics Method for Multiscale Modeling of Blood Platelet Phenomena Not Available Media:2007MSM PIQ Karniadakis.doc Media:2007MSM PP Karniadakis.ppt
12:30 - 12:45 Ching-Long Lin WG3, WG5 Multiscale Simulation of Gas Flow in the Human Lung Media:2007 MSM Poster_ChingLong.pdf Media:2007MSM PIQ ChingLong.doc Media:2007MSM PI ChingLong.ppt
12:45 - 1:00 Trent Guess WG6 Dynamic Neural Networks for System Identification of Knee Articulations Not Available Media:2007MSM PIQ Guess.doc Media:2007MSM PI Guess.ppt

1:00-2:00 Lunch on your own (Cafeteria downstairs)

2:00-4:00 (refreshments will be provided)

Poster Session with Live Demos and Concurrent Working Group Meetings 1, 3, 6, 7

Working Group Discussion Topic Location Presentation
WG 1 Not Available LHC Visitor's Center Media:WG1 Conclusions.doc
WG 3 Not Available LHC Auditorium Media:WG3 Conclusions.ppt
WG 6 Determination of computational priorities and challenges related to multiscale modeling in computational biomechanics OHPCC B1n-30Q Media:WG6 Conclusions.doc
WG 7 WG7 Discussion Topics LH Visitor's Center "Back Room" Alcove Media:WG7 Conclusions.pdf

4:00-5:00 WG 1, 3, 6, 7 Reports

5:20 Meet in lobby of Lister Hill to walk to Chatters and Clarion Hotel Shuttle

5:30 Happy Hour at Chatters, adjacent to the Clarion hotel

Thursday April 12, 2007

Breakfast on your own

7:30 Shuttle leaves Clarion Hotel for NIH Campus

8:00 – 8:30 Goals of the Day

Goals for Today (Grace Peng)

IMAG and MSM Wiki - Katie Serrano



8:30 - 9:30 Project Presentations

Time PI Name Working Group Poster Abstract(s) Poster (s) PI Questionnaire Presentation
8:30 - 8:45 Marco Cabrera WG3, WG2 Multi-scale modeling of time-course of muscle atrophy induced by Hindlimb Suspension Unloading Not Available Media:2007MSM PIQ Cabrera.doc Media:2007MSM PI Cabrera.ppt
8:45 - 9:00 James Bassingthwaighte WG2 Empirical Mode Decomposition: Development of a method for recognition of abnormalities in multiscale model solutions Not Available Not Available Media:2007MSM PI Bassingthwaighte.ppt
Multiscale Adaptive Modeling of the Cardiovascular System Not Available
9:00 - 9:15 Daniel Beard WG2 Not Available Not Available Not Available Media:2007MSM PI Beard.ppt
9:15 - 9:30 Andrew McCulloch (presented by Anushka Michailova) WG2 Not Available Not Available Not Available Media:2007MSM PI McCulloch.ppt


9:30 – 10:45 Project Presentations

Time PI Name Working Group Poster Abstract(s) Poster (s) PI Questionnaire Presentation
9:30 - 9:45 James Glazier WG4, WG5 Physical Mechanisms of Patterning Instabilities in the Formation of Vascular Network Not Available Media:2007MSM PIQ Glazier.doc Media:2007MSM PI Glazier.ppt
Pattern Formation in Avian Limb-Paddle Growth Not Available
Multi-Scale Modeling Based on the Glazier—Graner—Hogeweg Model Not Available
Dynamics of ECM Rearrangements during Embryonic Axis Patterning Not Available
9:45 - 10:00 Ernst Georg Luebeck WG4 Multiscale and Multistage Carcinogenesis in Barrett’s Esophagus Not Available Media:2007MSM PIQ Luebeck.pdf Media:2007MSM PI Luebeck.pdf
Mutant clone growth driven by the death of adjacent normal cells Not Available
Genetic Differences between Cells Reveals the History of Wounding and Mechanisms of Wound Healing Not Available
A Multi-Scale Model of Stem Cell and Crypt Dynamics in Carcinogenesis Not Available
Turnover in Epithelia is a Mechanism for the Formation of Clonal Multifocal Lesions Not Available
10:00 - 10:15 Bridget Wilson WG4 Mapping and Modeling ErbB Receptors On Cancer Cell Membranes During Signal Transduction Media:2007 MSM Poster_Wilson.pdf Media:2007MSM PIQ Wilson.doc Media:2007MSM PI Wilson.ppt
10:15 - 10:30 Denise Kirshner (presented by Tom Riggs) WG4 Random versus chemotactic movement of T cells toward Dendritic cells in the Lymph Nodes Media:2007 MSM Poster_Kirschner.pdf Media:2007MSM PIQ Kirschner.doc Media:2007MSM PI Kirschner.ppt

10:30 – 11:00 Break


11:00 – 12:00 Project Presentations

Time PI Name Working Group Poster Abstract(s) Poster (s) PI Questionnaire Presentation
11:00 - 11:15 Stanislav Shvartsman WG4 Quantatative Study of the Terminal Patterning System in the Drosophila Embryo Not Available Media:2007MSM PIQ Shvartsman.doc Media:2007MSM PI Shvartsman.ppt
11:15 - 11:30 Michela Taufer WG5 Assessment of Protein Flexibility in CHARMM-based Molecular Docking and Scoring: Preliminary Cross-Docking and Virtual Screening Results for HIV-1 Protease. Not Available Media:2007MSM PIQ Taufer.doc Media:2007MSM PP Taufer.pdf
DAPLDS: a Dynamically Adaptive Protein-Ligand Docking System based on Multi-Scale Modeling Not Available
11:30 - 11:45 David Cai WG5 Architectural and synaptic mechanisms underlying coherent spontaneous activity in V1 Media:2007 MSM Poster_Cai1.ppt Media:2007MSM PIQ Cai.doc Media:2007MSM PI Cai.ppt
Modeling the spatiotemporal cortical activity associated with the line-motion illusion in primary visual cortex Media:2007 MSM Poster_Cai2.ppt
Reverse-Time Correlation and the Architecture of Neuronal Networks Media:2007 MSM Poster_Cai4.ppt
Orientation Selectivity in Visual Cortex by Fluctuation-Controlled Criticality Media:2007 MSM Poster_Cai3.ppt
11:45 - 12:00 Niles Pierce WG5 NUPACK: a web-based tool for the analysis and design of nucleic acid systems Not Available Media:2007MSM PIQ Pierce.doc Media:2007MSM PI Pierce.pdf

12:00-1:00 Lunch on your own


1:00-3:00 (refreshments will be provided)

Poster Session with Live Demos and Concurrent Working Group Meetings 2, 4, 5

Working Group Discussion Topic Location Presentation
WG 2 Scientific Collaborations in Cardiac and Skeletal Muscle Physiology LH Visitor's Center "back room" alcove Media:WG2 Conclusions.ppt
WG 4 Not Available LH Auditorium Media:WG4 Conclusions.pdf
WG 5 Challenges in designing and deploying large-scale computer systems for multi-scale modeling applicationsanics OHPCC B1n-30Q Media:WG5 Conclusions.pdf

3:00-3:45 WG 2, 4, 5 reports

3:45-5:15 MSM Discussion

Optimal model sharing strategy for all working groups

Needs assessment of MSM

Discussion – Summary and Next Steps

5:15 - 5:30 Update on IEEE/EMBS Special Issue for Multiscale Modeling – Semahat Demir

5:30 - 5:45 Summary of March 1-2, 2007 NSF Workshop on Dynamical Systems – Kurt Anderson

5:45 - 6:00 Closing Remarks - Grace Peng


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