JSim Consolidated Model Database
Showing 1 - 50 of 433 models found. [New Search]
A compliant 1 compartment lung with resistance to air flow, driven by external positive pressure ventilator.
- Key terms: lung compliance, resistance, RC circuit, lung mechanics, airflow in trachea, tidal volume, positive pressure ventilation, reference, tutorial
- OneAlvLung.Assist
A compliant 1 compartment lung with resistance to air flow, driven by intrapleural negative pressure (chest or diaphragmatic breathing) or by a positive pressure ventilator or both together, even competing, interfering..
- Key terms: lung compliance, resistance, RC circuit, lung mechanics, airflow in trachea, tidal volume, positive pressure ventilation, chest or diaphragmatic breathing, tutorial
- OneAlvLung.Chest
Exchange of gas in external air into a linearly compliant lung with calculation of inhaled gas concentration in lung over a series of breaths.
- Key terms: lung, non-linear, compliance, resistance, RC circuit, mechanics, airflow, trachea, tidal volume, positive pressure, ventilation, tutorial
- OneAlvLung.GasExch
Airflow between atmosphere and lung modeled with 2 compartments representing the non-exchanging space (bronchus) and exchanging space (alveolus).
- Key terms: lung, non-linear, compliance, resistance, RC circuit, mechanics, airflow, trachea, tidal volume, positive pressure, ventilation
- 2CompLung_Air
"A nonlinear model combining Pulmonary Mechanics and Gas Concentration Dynamics." IEEE Trans.,BME-29, 1982, p. 629-641. Lutchen, F.P. Primiano Jr., G.M. Saidel
- Key terms: lung, tidal volume, positive pressure, ventilation, pendelluft, publication, oscillating flow
- Lutchen
This model represents airway with one bronchus, one bronchiole, and an alveolus.
- Key terms: lung compliance, resistance, RC circuit, lung mechanics, airflow in bronchus, tidal volume, positive pressure ventilation, airway, PV curves, bronchus, bronchiole, alveolus
- BronchBronchiolAlv
Models a two compartment, 1 solute, T1-T2 (facilitated 4-state transporter. Includes binding steps and transmembrane flip rates for free and occupied transporters.
- Key terms: two compartment, facilitated transporter, binding constants, single site, noncompetitive binding, four state transporter, tutorial
- Transp1sol.Comp2
A two compartment one solute facilitated transporter model with flow through one compartment. Includes binding steps and transmembrane flip rates for transporter.
- Key terms: two compartment, facilitated transporter, transmembrane, flow, two region, single transporter, one solute, no competition
- Transp1sol.Comp2F
A two region axially-distributed model with flow and a facilitating two-sided transporter (T1-T2) for one solute.
- Key terms: axial gradients, solute-solute competition, permeability, surface area, BTEX, spatially distributed, convection, diffusion, reaction
- Transp1sol.Distrib2F
Facilitating Transporter for 2 competing solutes including binding steps. Shows countertransport facilitation/inhibition Enymatic conversion in V2.
- Key terms: Two solutes, competing solutes, enzymatic reaction, transmembrane flip, countertransporter, six state transporter, tutorial, Transp2sol, two compartment
- Transp2sol.Comp2
Facilitating Transporter for 2 competing solutes including binding steps. Shows countertransport facilitation/inhibition. Substrate A is converted to B in region 2.
- Key terms: Two solutes, competing solutes, enzymatic reaction, transmembrane flip, countertransporter, six state transporter, Flow, Tutorial
- Transp2sol.Comp2F
An axially-distributed facilitating transporter for two competing solutes, A and B, including binding steps, with input via flow. Shows countertransport facilitation/inhibition. There is Enzymatic conversion A -> B in V2.
- Key terms: axial gradients, solute-solute competition, permeability, surface area, BTEX, spatially distributed, convection, diffusion, reaction
- Transp2sol.Distrib2F
(Matlab) Three-Wall Segment (TriSeg) Model Describing Mechanics and Hemodynamics of Ventricular Interaction.
- Key terms: Pulmonary hypertension, Heart, Septal motion, Adaptation, Stress, Strain, Myofiber, Cardiac mechanics, Publication, PMID19718527
- CircAdapt_TriSeg_2009
An axially distributed two region model with a two-sided passive transporter (PSg) through clefts and a one-sided Michaelis-Menten transporter (PSc) for membrane transport.
- Key terms: Axially Distributed, two region, capillary-tissue exchange, facilitated transport, plasma, interstitial fluid region, radial diffusion, tutorial, Michaelis-Menten
- TranspMM.1sided.Distrib2F
An axially distributed two region two-sided Michaelis-Menten transporter model, with permeation across the capillary wall via clefts (PSg) and cell transporters (PSc).
- Key terms: Axially Distributed, two region, capillary-tissue exchange, facilitated transport, plasma, interstitial fluid region, radial diffusion, tutorial, Michaelis-Menten
- TranspMM.2sided.Distrib2F
A capillary-ISF-cell convection diffusion model, modified BTEX30 with a Michaelis-Menten saturable transporter on the pc membrane. It is represented by two separated and independent unidirectional transporters, each governed by the fractional saturation in the source compartment, i.e. by the concentration in the ISF to define PSISF2pc, and in the pc, Cpc, to define PSpc2ISF, the conductance via the carrier from pc to ISF. A three region two-side Michaelis-Menten transporter model.
- Key terms: Michaelis-Menten, BTEX30, Blood tissue exchange, 3 region, interstitial fluid, parenchymal cell, axial diffusion, passive barrier, interendothelial clefts, capillary mean transit time
- TranspMM.2sided.Distrib3F.2Ch
A two region two-sided Michaelis-Menten transporter with bolus sweep multiple indicator dilutions.
- Key terms: Bolus Sweep, Multiple Indicator dilution model, serotonin tracer curves, four region, tutorial, Michaelis-Menten, Data
- TranspMM.2sol2sided.BolusSw.MID4
Two region capillary-tissue exchange model with both passive and Michaelis-Menton (MM) transport of two solutes with MM reaction of A to B in interstitial fluid region.
- Key terms: transporter, Michaelis-Menten, capillary-tissue exchange, axial gradients, solute-solute competition, permeability surface area, BTEX spatially distributed, convection, diffusion reaction, tutorial
- TranspMM.2sol2sided.Distrib2F
4 Region Axially Distributed Multi Path Michaelis-Menten Model applied to analysis of serotonin uptake by lung tissue following injection into pulmonary artery.
- Key terms: four region, Michaelis-Menten, two-sided, facilitated transporter, serotonin, diffusion, MMID, Multiple indicator dilution, multipath, flow heterogeniety, bolus sweep, tracer, vascular reference, capillary, lung, serotonin transport, pulmonary uptake, tutorial, Data
- TranspMM.2sol2sided.BolusSw.MMID4
Hemoglobin CO2 saturation curve at varied levels of PO2 and pH. Temperature and 2,3-DPG concentration are assumed constant. Based on Dash 2010 paper.
- Key terms: hemoglobin, oxygen, carbon dioxide, saturation, Haldane, Bohr, acidity, pH, blood gases, Hill equation, solubility
- HbCO2
This model is based on Athanasiades et al. energy analysis of a nonlinear model of the normal human lung. J Biol Sys. 8(2):115-39, 2000.
- Key terms: Virtual Soldier, Lumped parameter, Airways, Alveoli, Respiration, Publication, Respiratory mechanics, Viscoelasticity, Chest Wall
- Athanasiades_2000
Equilibrium conc for increasing kon for two compartment model. Figure 2 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states
- Anderson_JC_2007_fig2
Volume of Distribution of equilibrium binding and unsteady state. Figure 3 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states
- Anderson_JC_2007_fig3
Tracer added after tracee and binding site have equilibrated. Figure 4 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states
- Anderson_JC_2007_fig4
Tracer transients Slow versus fast binding. Figure 5 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states
- Anderson_JC_2007_fig5
Optimization tracer fit of pseudo two equation fit to three equation fit. Figure 6 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states
- Anderson_JC_2007_fig6
Two compartment model. Optimization to fit 2-Eq model to 3-Eq model solution assuming the absence of ligand binding in V1 or V2. Figure 2 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states
- Anderson_JC_2007_fig7
Pulse responses in axially-distributed three region model. Figure 11 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states
- Anderson_JC_2007_fig11
Pulse responses of Nth order Poisson operator with N tanks varied from 2 to 109 tanks in seried. Figure 12 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states, SIMVOL30
- Anderson_JC_2007_fig12
MID curve data fitted to three region PDE and serial compartment models. Figure 13 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states, SIMVOL30, Data, Publication
- Anderson_JC_2007_fig13
Fitting Intravascular reference curve to serial stirred tank model. Figure 14 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states, SIMVOL30, Data, Publication
- Anderson_JC_2007_fig14
MID data curves fit to stirred tank model - compare 1 tank versus 15 serial tanks. Figure 15 of "Tracers in Physiological Systems Modeling".
- Key terms: tracer, tracee, metabolic physiologic modeling, lumped compartmental versus spatially distributed systems, capillary-tissue exchange, membrane transporters, enzyme reactions, steady state versus transient states, SIMVOL30
- Anderson_JC_2007_fig15