PDF iconNatcher Atrium poster layout.pdf


Scales CoveredMSM MethodGroupPoster NumberTitleLast NameFirst NameAbstract/Poster File
Credibile practice guideline applicable to all scales of modeling and simulationThe Committee on Credibe Practice of Modeling and Simulation in Healthcare:
1. Conducted an internal survey of Committee members via discussion within task teams
2. Sythecized to yeild the Committee has drafted its perspectives on “The Ten Simple Rules of Credible Practice of M&S in Healthcare
3. Solicited input from the broader M&S community through an online survey
4. Consolidating the Committee's perspective and community survey results to establish "Guidelines for Credible Practice of Modeling and Simulation in Healthcare"



Guidelines for Credible Practice of Modeling and Simulation in Healthcare


PDF iconMulugeta Lealem.pdf

Poster: PDF iconPoster IMAG_MSM2017.pdf


Modeling osmotic transients during exercise

BassingthwaiteJamesFileHL122119_Bassingthwaighte James.docx

Impact of Compartmentalization and Cell Shape on Signaling Pathways in Cancer

SpillFabianFileCA177799_Zaman Muhammad_Spill Fabian.docx
molecularGeneral-purpose constrained optimization using quadruple-precision floating-point arithmetic183General-purpose Software for Systems BiologySaundersMichaelPDF iconGM102098_Saunders Michael.pdf
enzyme, pathway, cellular, consortiagenome scale metabolic models, temporally resolved reaction diffusion PDEs, enzyme kinetics, agent based cellular models284

in silico and in vitro analysis of resource allocation in a chronic wound biofilm consortia

CarlsonRossFileEB019416_Carlson Ross.docx

Multiscale Modeling of Blood Flow and Platelet Mediated Thrombosis

BluesteinDannyMicrosoft Office document iconIMAG MSM Multiscale Platelets Poster (2017).pdf

Computational Game Theory for Antibody Design



FileVorobeychik Yevgeniy.docx

Understanding the Role of Mitochondrial Cristae Structure on Energy Metabolism through Simulation

AfzalNasrinFileHL116321_Lederer Jonathan_Afzal Nasrin.docx
molecular, supramolecular, cellularPDEs, spatial stochastic19

Multiscale Modeling of Wound Healing

HaughJasonFileEB018816_Haugh Jason.docx

molecules (1e-2 Da to 1e6 Da), cell

General-purpose constrained optimization using quadruple-precision floating-point arithmetic210

A multiscale model of metabolism and protein expression predicts the response of E. coli to oxidative stress

YangLaurenceFileGM102098_Saunders Michael_Yang Laurence.docx
molecular, cellular, networkUncertain ODEs111Multiscale Modeling of the Mammalian Circadian Clock: The Role of GABA SignalingHensonMichael

PDF iconEB021956_Henson Michael.pdf

PDF iconnih_poster_henson.pdf

cell, tissue & hours to weeksagent-based and finite element analysis212

Spatial Scaling in Multiscale Models: A Method for Coupling Agent-based and Finite-element Models of Tissue Remodeling


FileHL127654_Holmes Jeffrey_Lee Jia-Jye.docx

PDF icon2017 IMAG_JJLee_Final.pdf


Mechanistic Models, Model Mechanisms, and Computational Models of Explanation for Biological Phenomena

HuntAnthonyFileEB017695_Lytton William_Hunt Anthony.docxPDF iconPoster Mechanistic Models.pdf
molecular, cellular, tissue,
organ, mice, strains;
in vivo & in vitro
software objects & logic mapped explicitly to
biological behavior & structure through DES

Is the Mechanism of APAP Toxicity In Vivo & In Vitro really the same?  A model mechanism based explanation of the in vitro–in vivo disconnect


FileHunt Anthony_Smith Andrew.docxPDF icon Poster InVitro-InVivo Disconnect.pdf

cell, tissue, system finite element analysis, lumped parameter circulation model115Computational model of heart remodeling following relief of hemodynamic overload in a biventricular canine heart modelYoshidaKyoko

PDF iconHL127654_Holmes Jeffrey_Yoshida Kyoko.pdf

PDF icon2017 IMAG_KY_final.pdf

  216Nonlinear mechanics of fibrin networksAlberMarkPDF iconHL116330_Alber Mark.pdf

Structural biomechanics of platelet-driven clot contraction

KimOlegFileHL116330_Alber Mark_Kim Oleg.docx
  218Multiscale models of blood clottingXuZhiliangFileHL116330_Alber Mark_Xu Zhiliang.docx
Genetic, cellular, tissueODE,genetic algorithm119Linking Gene Dynamics to Intimal Hyperplasia – A Predictive Model of Vein Graft AdaptationCasarinStefanoFileHL119178_Berceli Scott_Casarin Stefano.docxPDF iconIMAG10th anniversary_SC1.pdf
Cellular, Breast tissueFinite Element Analysis, agent-based model220Clinical study and multiscale modeling to predict the esthetic outcome of Breast Conservative TherapyLesageAnne-CecileFileGarbey Marc_Lesage Anne-cecile.docxPDF iconposter_BCT_March2017.pdf

High-Fidelity Controlled-Resolution Atlas and Deformable Model-based Anatomical Modeling for Medical Simulation and Therapy Planning

PDF iconposterIMAG2017NIH_Michele.pdf


FileAudette Michel.docx

PDF iconAudette_poster.pdf

Individual + PopulationObject Oriented, Microsimulation, Database interface222

The Reference Model Interface with ClinicalTrials.Gov

BarhakJacobFileBarhak Jacob.docx
Cellular, Large-Scale Network, Bulk TissueNEURON, Admittance Method123

Improving Cortical Electrode Placement and Stimulation via Co-Simulation of Large-Scale Compartmental Neuronal and Multi-Resolution Admittance Method Models

BinghamClaytonFileGM104604_Lazzi Gianluca_Bingham Clayton.docx
Large-Scale NetworkNEURON224Spatio-Temporal Patterns Revealed by a Large-Scale Model of the Hippocampal Entorhinal-Dentate-CA3 System: Emergence of Clustered ActivityYuGeneFileGM104604_Lazzi Gianluca_Yu Gene.docx
Cellular, PopulationODEs125

Temporal Dynamics of Macrophage Plasticity in Bone Metastatic Prostate Cancer

LynchConorFileCA202958_Basanta David_Lynch Conor.docx
Molecular, cellular, populationAgent-based226Modeling the ecosystem of bone metastases: insights from a multi scale, multi modeling approachBasantaDavidFileCA202958_Basanta David_Araujo A.docxPDF iconCook_AACR and Moffitt Symposium 2015.pdf
Molecules, Channels, Cells, Neural Network, Organ SystemAgent-based, ODEs127

Integrating Microscopic Variability in Systems Modeling

DickThomasFileNS069220_Rybak Ilya_Dick Thomas.docx
  228Multiscale modeling of the brain motor cortex circuitsDura-BernalSalvadorPDF iconEB017695_Lytton William_Dura Salvador.pdf
Molecular scales (angstrom to nanometer)Full atomistic molecular simulation, Recombinant DNA technology129

Design of Biomaterial Bioinorganic Interfaces Related to Mineralization

EbrahimiDavoudFileEB014976_Kaplan David_Ebrahimi Davoud.docx
atomic to nmfully atomistic and coarse-grained molecular dynamics230

Thermal Response of Silk-Elastin-Like Protein Hydrogels: Integrating Experiments and Multiscale Computational Modeling

YeoJingjieFileEB014976_Kaplan David_Jingjie Yeo.docx
  131Multiscale Modeling of Collagen IV Network: Insights into the Structural Basis of PathologiesSarkarBiplabPDF iconEB014976_Kaplan David_Sarkar Biplab.pdf
  232Modeling of the relation between degradation and mechanical properties of a collagen fibril: A precursor examination towards understanding cartilage healthDhaherYassinPDF iconEB015410_Dhaher Yassin.pdf

Prediction of EMG based on neural firing rates using stochastic dynamical operators

SangerTerenceFileEB021921_Sanger Terence.docx
milliseconds to 24 hoursStatistical thermodynamics234

Multi-scale Modeling of Circadian Rhythms: From Metabolism to Regulation and Back in 24 hours

CannonWilliamFileEB022546_Cannon William.docxPDF iconposter_ProjectOverview_CRA-jz2.pdf
  135Electrical Stimulation Waveform Design Towards Increasing the E ectiveness of Retina Prosthetic DevicesLoizosKylePDF iconGM104604_Lazzi Gianluca_Loizos Kyle.pdf
Tissue (250um) – Cell (20um), Time ranges from 0.01 second to minutes.Agent based, PDE & ODE236

Comparison of Models of Hepatic Lobules at Varying Levels of Detail


PDF iconSluka_Models of Hepatic Lobules.pdf

FileGM111243_Glazier James_Sluka James.docx

Tissue (250um) – sub-Cell (5um), Time ranges from hours to months.Agent based, PDE & ODE137

Coupled multiscale modeling and pathway analysis for prediction of drug efficacy in cystic kidney diseases


FileGM111243_Glazier James.docx

PDF iconGlazier_CystPoster.pdf

arterioles 20-80 um, NO 0-100 nM, PO2 0-100 torr, time 0.1 s to minutes

Statistical data analysis238

Nitrite-mediated Vasodilation Quantified from In Vivo Studies in Rat Mesentery

BuerkDonaldFileHL116256_Jaron Dov_Buerk Donald.docx
Microcirculatory tissue and arteriole: 1-100 μm, Steady stateFinite element analysis, mass transport ODEs, cellular reaction kinetics139

A Mathematical Model for the Role of N2O3 in Enhancing Nitric Oxide Following Nitrite Infusion


FileHL116256_Jaron Dov_Liu Yien.docx

PDF iconLiu Jaron Poster.pdf

Nanoscale to Microscale (Surface Receptors, Calcium, Nanomotors, Neuron)

IEEE Std 1906.1TM-2015; and Reference Code NEMo, doi: 10.1109/TMBMC.2015.2465513



Applying Nanocommunication Modeling to Understand Calcium Ion Influx in Neurons and Impact on Kinesin Axonal Transport of BDNF Vesicles

PaluhJanetPDF iconPaluh Janet poster.pdf

Modelling the Airway Epithelium to Facilitate Cystic Fibrosis Drug Development

CorcoranTimothyFileHL131046_Corcoran Timothy.docx

Sub-cellular to whole body lymphatic system, 10^-3 sec to hours

PDEs, ODEs, ABM242

Mass Transport in the Lymphatic Vessels and Nodes

MooreJamesFileMoore James.docx
Mesoscale & MicroscaleODEs, Discrete and Spatial Stochastic Simulation,143

StochSS: An Integrated Development Environment for Simulation and Analysis of Discrete Stochastic Biochemical Models

PetzoldLindaFilePetzold Linda.docxPDF iconStochSS_Petzold.pdf

A multiscale systems biology model to characterize antitumor immunity and evaluate biomarkers for immunotherapeutics

GongChangFileCA138264_Popel Alexander_Gong Chang.docx
molecular, cellular, tissue, organ and systemic levels; days to yearsODEs, algebraic equations, probabilities145

Systems Pharmacology Multiscale Model to Optimize Mono- and Combination-Therapy Regimens for Immune Checkpoint Inhibitors and Identify Potential Biomarkers

MilbergOlegFileCA138264_Popel Alexander_Milberg Oleg.docx
spatial/temporalagent-based, ODE/PDE246

Multiscale modeling of vascularized bone regeneration in hybrid constructs of soft collagen gels and rigid scaffold

TanHuaFileAR069395_Zhou Xiaobo_Tan Hua.docx
  13High-Performance and Quantum Computing for Solving Biological ProblemsDifeliceRosaPDF iconGM103804_Nuzhdin Sergey_Difelice Rosa.pdf
  248Genome-wide prediction of minor groove electrostatics enables biophysical modeling of protein-DNA bindingChiuTsu-PeiFileGM103804_Rohs Remo_Chiu Tsu-Pei.docx
  149Autonomic, Metabolic, and Mechanical Control of Coronary Blood FlowBeardDanielFileHL118738_Beard Daniel.docx
molecular, cellular, tissue; seconds to yearsagent-based, ODE, PDE250A Multi-scale Systems Pharmacology Approach to TB TreatmentLindermanJenniferFileHL131072_Kirschner Denise_Linderman Jennifer.docx
Individial-Population scalesMultiscale Imaging-based Cluster Analysis (MICA), Machine Learning151Multiscale imaging-based cluster analysis of a cohort of current smokersLinChing-LongFileHL114494_Lin Ching Long.docx
Spatial/TemporalAgent-based, ODE/PDE252Systematically understanding immunity leading to CRPC progressionJiZhiweiFileCA166886_Zhou Xiaobo_Ji Zhiwei.docx
  153Sugar-Sweetened Beverage Warning Labels in Baltimore, Philadelphia and San Francisco: A Simulation StudyFergusonMarieFileHD086861_Lee Bruce_Ferguson Marie.docx
  254A Parallel Fluid Solid Coupling Tool Using Lammps and PalabosTanJifuPDF iconHL131053_Diamond Scott_Tan Jifu.pdf

Development of a multiscale skin barrier model for de novo, in silico prediction

TasseffRyanFileTasseff Ryan.docx

From the minute to the year, from the individual staff/patient scale to the OR suite and peripheral area scale.

hybrid ABM - stochastic ODE



Multiscale Modeling of Surgical Flow in a Large Operating Room Suite: Understanding the Mechanism of Accumulation of Delays in Clinical Practice


FileGarbey Marc.docx

PDF icon MSM_multiscaleABM_surgery_v6.pdf

  157Multiscale Multiphysics Model of Thrombus BiomechanicsYazdaniAlirezaPDF iconHL116323_Humphrey Jay_Yazdani Alireza.pdf
molecular, cellular, tissue, organanimal models of pressure- and volum-overload, mathematical models of growth and remodeling, computational multiscale models258Multiscale modeling of myocardial growth and remodelingKuhlEllenFileHL119578_Guccione Julius_Kuhl Ellen.docx

Molecular Scale Prediction of Lidocaine Interaction with the Pore Domain of Human NaV1.5

DeMarcoKevinFileHL126273_Clancy Colleen_DeMarco Kevin.docx

Multiscale Analysis of Trauma

SinnoTalidFileHL131053_Diamond Scott_Sinno Talid.docx

Emulating Body Tissue Architectures for Computer-controlled Smart Material Design and Manufacture

Knothe-TateMelissaFileKnothe-Tate Melissa.docx
  262Motion of spheroidal nanoparticles in a cylindrical vessel flow: accurately resolving the hydrodynamic interactions and stochastic thermal motionAyyaswamyPortonovoFileU01 EB016027_Eckmann David_Ayyaswami Portonovo_Hydrodynamics.docx

Biophysically inspired model for functionalized nanocarrier adhesion to cell surface and the development of next-generation pharmacokinetic models

RadhakrishnanRaviFileU01 EB016027_Eckmann David_Radhakrishnan Ravi_Cadhesion.docx

A multiscale model for predicting margination effects and transport of nanogels in blood vasculature: comparison of Dynamical Density Functional Theory and Monte Carlo based approaches

EckmannDavidFileU01 EB016027_Eckmann David_Marginations.docx
hundreds of microns to tens of cm (acinus to trachea)PDEs (wav eqn), 3D-to-1D coupling, fractal methods165The Multiscale Audible Human ProjectRoystonThomasPDF iconRoyston Thomas_Henry Brian.pdfPDF iconNIH IMAG Poster Final V2.pdf
molecular to cellularPDEs, stochastic simulations266Catch bonds at T cell interfacesAbelSteven

PDF iconAbel Steven.pdf

PDF iconabel_poster_IMAG_2017.pdf


Cell Death as a Trigger for Morphogenesis of Bacterial Colonies

AguilarBorisFileAguilar Boris.docx
Molecular, Cellular, Individual, PopulationAgent-based model, Genetic Algorithms, Random Dynamical Systems2


Really Big Data from HPC-enabled biomedical agent-based modeling:
Pathways to Precision Medicine

PDF iconAn Gary.pdf

PDF icon IMAG 2017 Really Big Data V2.pdf

sub-cellular, cellular, tissue

agent-based models, finite element models


169Computational models predict the effect of anti-fibrotic therapies in Duchenne muscular dystrophyKelleyVirgilioPDF iconAR06393_Blemker Silvia_Virgilio Kelley.pdf
tissue, Cellular, sub-cellularAgent based model, ode, pde270A Hybrid Multiscale Tumor Growth ModelLimaErnestoPDF iconCA174706_Yankeelov Thomas_Lima Ernesto.pdf
  171Growth Control in Cancer: An Computational Model of YAP/TAZ Integrating cell-ECM Mechanosensing and Hippo pathwaySunMengFileCA177799_Muhammad Zaman_Sun Meng.docx
  272Stochastic Simulation of Functional Knee Mechanics Enabled via Statistical Shape Modeling and High Throughput ComputingSmithColin

FileEB015410_Daher Yasin_Smith Colin.docx

PDF iconsmith et al_IMAG2017_poster.pdf

  173Multi-scale mechanics of the tendon-to-bone attachmentThomopoulosStavrosFileEB016422_Thomopoulos Stavros.docx
  274Analysis of Multielectrode Data from CPG Networks Using
a Stochastic Framework
Abolfath-BeygiMaryamPDF iconEB021921_Sanger Terence_Abolfath-Beygi Maryam.pdf
 body/organ/tissue/cellPDE / finite element analysis22Democratization of Modeling & Simulation in BiomechanicsErdemirAhmet

PDF iconErdemir Ahmet.pdf

PDF iconmsm_2017-poster.pdf

276Mesoscopic modeling of biomechanics and biorheology of red blood cells in type 2 diabetes mellitusChangHung-yuPDF iconHL114476_Karniadakis George_Chang Hung-yu.docx.pdf



Patient-specific modeling of biomechanics and biorheology of red blood cells in sickle cell anemia

LiXuejinFileHL114476_Karniadakis George_Li Xuejin.docx
  278Multiscale modeling of cardiac growthLeeLik ChuanFileHL119578-03_Guccione Julius_Lee Lik Chuan.docx
cellular ~ tissue agent-based & ODE/PDE179Multiscale Modeling of Multiple Myeloma Using Biocellion FrameworkKangChris

PDF iconKang Chris_Kahan Simon.pdf

PDF iconMultiscale Modeling of Multiple Myeloma Using Biocellion Frameworkv2.pdf

cellular ~ tissueagent-based & ODE/PDE280

Biocellion: a large capacity modeling platform for multicellular biological systems


FileKang Seunghwa.docx

PDF iconBiocellionPoster-PNNL48x36.pdf

All scalesBayesian inference, probabilistic programming181Stan: A Platform for Scalable Bayesian InferenceBetancourtMichael

PDF iconBetancourtAbstract.pdf

PDF iconBetancourtStanPoster.pdf

molecular, subcellular, cellular, layer, column, area, multiareaODE, event-driven282Embedded Ensemble Encoding - a new theory of brain cortex functionLyttonWilliamPDF iconLytton William_Antic Srdjan.pdf
molecular, subcellular, cellular and networksPDEs, Deterministic and Stochastic simulation15Expanding NEURON to bridge electrophysiology, chemical, and network scales: simulations of ischemic strokeNewtonAdamPDF iconLytton William_McDougal Robert_Newton Adam.pdf
Multiple/All ScalesAgent-based Modeling, Adaptive Model Exploration24From Desktop to Large-Scale Model Exploration with EMEWSOzikJonathanPDF iconOzik Jonathan.pdf
  185A detailed rule-based computational model for the interaction of VEGF pathway with thrombospondin-1 integrating multiple signaling modules: Implications for pro-angiogenic therapeutic interventionsBazzaziHojjatPDF iconPopel Alexander_Bazzazi Hojjat.pdf
Behavioral, Population, InternationalODE, Deterministic286

Effectiveness of UNAIDS targets and HIV vaccination across 127 countries

FitzpatrickMeaganFileGM105627_Galvani Alison_Fitzpatriz Meagan.docx
Micro to MacroFDM of PDEs, DEM, CFD, Machine Learning187

Hip Prostheses Lifetime Prediction via Simulation-based Engineering

HiggsC. Fred

Microsoft Office document iconHiggs_abstract.doc

PDF iconHiggs_poster.pdf


Parallel Discrete Event Simulation of Neurons

TropperCarlFileTropper Carl.docx
cellular, tissue FEM, ODE 189Comparison of cellular- and tissue-scale models of dynamic contrast-enhanced MRIWoodallRyan

PDF iconWoodall Ryan.pdf

PDF iconwoodall_IMAG_NIH_2017.pdf

Spatial, Temporal, PopulationMultiscale statistical-based SolidWorks CAD modeling290Parametric Anatomical CAD Model Generation with Silicone Phantom Fabrication Tools for Validation StudiesBergeronClint

PDF iconTaylor Charles_Bergeron Clint.pdf

PDF icon2017 IMAG - Clint Bergeron - Parametric Aortic Root Poster.pdf

Temporal, PopulationEvent-driven, Matlab, Simulink Simscape, Finite State Modeling291Development of a Pulmonary Simulator Utilizing Windkessel Modeling Techniques for Simulating Various Patient Populations within a Mock Circulatory SystemKingJacob

PDF iconTaylor Charles_King Jacob.pdf

PDF icon2017 IMAG - Jacob King - Pulmonary Simulator Poster.pdf

Temporal, PopulationEvent-driven, Matlab, Simulink Simscape292Evaluation of ventricular assist systems through target patient modelsTaylorCharlesPDF iconTaylor Charles.pdf
  193Exploring Polygenic Mechanisms of Pathogenesis and Treatment Resistance in Childhood Absence Epilepsy with a Multiscale Thalamocortical ModelKnoxAndrewFileLytton William_Know Andrew.docx
Molecualr, SubcellularMATLAB, NEURON294

Modeling Postsynaptic Current at the Glutamatergic Synapse of a CA1 Pyramidal Neuron: Development and Adaptation for Multi-Scale Simulations

HuEricFileGM104604_Lazzi Gianlucca_Reusbucks Thomas_Hu Eric.docx
Microscopic, Mesoscopic, Sub-macroscopic and MacroscopicMolecular Dynamic, Stochastic Simulations, Partial Differential Equation, and Bayesian scientific computing195Multi-scale Modeling of Gas Transport through Channels in Living CellsOcchipintiRossanaPDF iconGM111251_Boron Walter_Occhipinti Rossana.pdf

Multiscale Model of Facet Capsule Mechanobiology

BarocasVictorFileEB016638_Barocas Victor.docx
Molecular, cellularODE, standard format, SBML197

Building Reproducible Dynamical Models with Tellurium 2.0: A Case Study using EGFR/Erk

SauroHerbertFileSauro Herbert.docx
 Any/All Applicability analysis298Applicability analysis of validation evidence for biomedical computational modelsPathmanathanPras

PDF iconPathmanathan Pras abstract.pdf

PDF iconPathmanathan Pras Poster.pdf

Cellular, tissueEvent-driven199A Comparative Modeling Study on Intestinal Crypt Dynamics of Steady State and After RadiationHuShaowenFileHu Shaowen.docxPDF iconCryptModel_IMAG_v2.pdf
 Molecular, cellularEvent-based2


Calculation of deletion, inversion, and ring spectra using a computational model of the radiation-induced chromosome aberrations with stochastic and amorphous particle tracksPonomarevArtem

FilePonomarev Artem_Plante Ianik.docx

PDF icon ArtemPonomarevPoster.pdf

Titles displayed in bold letters are those of posters from current U01 awardees.


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